Abstract: Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula; ##STR1## WHEREIN Me represents the sodium, potassium, or lithium ion and R represents the sulfite, bisulfite, metabisulfite, dithionate, hydrosulfite, and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color on pharmaceutical preparations containing the same. The method for the preparation of cholin-salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.
Type:
Grant
Filed:
February 23, 1978
Date of Patent:
April 3, 1979
Assignee:
Mundipharma, AG
Inventors:
William Kelly, deceased, John Kelly, personal representative, Alfred Halpein
Abstract: Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula, ##STR1## WHEREIN Me represents the sodium, potassium or lithium ion and R represents the sulfite, bisulfite, metabisulfite, dithionate, hydrosulfite and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color in pharmaceutical preparations containing the same. The method for the preparation of choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.
Type:
Grant
Filed:
December 22, 1976
Date of Patent:
July 4, 1978
Assignee:
Mundipharma AG
Inventors:
William Kelly, deceased, by John Kelly, joint personal representative, Alfred Halpern