Abstract: The present invention relates to dehumidification equipment and more particularly, to a dehumidification system and method for use in hazardous locations. In particular, there is provided a desiccant wheel assembly for use in a dehumidification system. The desiccant wheel assembly includes a cabinet and a desiccant wheel rotatively mounted within the cabinet. The desiccant wheel has a core impregnated with a desiccant material and an electrically conductive outer shell surrounding the core. Means are provided for driving rotation of the desiccant wheel within the cabinet. The desiccant wheel assembly further includes a static control device connected to a ground and associated with the desiccant wheel for discouraging the build-up of electrostatic charges on the desiccant wheel during rotation thereof. A dehumidification system comprising such a desiccant wheel assembly is also described along with a method for dehumidifying air in an enclosed space using a desiccant wheel dehumidification system.