Abstract: An agent carrier delivers an agent to biological tissues by one or more modalities. The modality of delivery may be one or more transportation stimulus that causes the agent to be transported through the agent carrier. The transportation stimulus also enhances or permits penetration of the agent into the tissue. The agent carrier has an agent carrier body that is configured to retain the agent within the agent carrier body. The agent carrier body has a tissue-contacting surface for engaging tissues under treatment. Application of the transportation stimulus causes transportation of the agent through the agent carrier body to the tissue-contacting surface.