Abstract: To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts and suppresses lung fibrosis without injuring alvocar epithelial cells. A pharmaceutical composition for treating fibrosis, the pharmaceutical composition comprising a compound of formula (I) or formula (II): wherein in formula (I), R1 represents a C1-4 alkyl group optionally substituted with a halogen atom, and l represents an integer of 3 to 6; and in formula (II), n represents an integer of 8 to 12, or a pharmaceutically acceptable salt thereof or a solvate of the compound or the salt thereof.
Type:
Grant
Filed:
September 26, 2019
Date of Patent:
September 24, 2024
Assignees:
LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY
Abstract: A pharmaceutical composition including a lecithinized superoxide dismutase, for treating or preventing a disorder associated with administration of an anticancer agent. A method for treating or preventing a disorder associated with administration of an anticancer agent, including administering a lecithinized superoxide dismutase to a subject in need thereof. The disorder associated with administration of an anticancer agent is a disorder selected from a neurological disorder, a liver disorder, drug-induced deafness, a kidney disorder, myelosuppression, and a combination of one or more thereof.
Type:
Application
Filed:
May 17, 2022
Publication date:
August 8, 2024
Applicants:
LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY
Abstract: To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts and suppresses lung fibrosis without injuring alvocar epithelial cells. A pharmaceutical composition for treating fibrosis, the pharmaceutical composition comprising a compound of formula (I) or formula (II): wherein in formula (I), R1 represents a C1-4 alkyl group optionally substituted with a halogen atom, and l represents an integer of 3 to 6; and in formula (II), n represents an integer of 8 to 12, or a pharmaceutically acceptable salt thereof or a solvate of the compound or the salt thereof.
Type:
Application
Filed:
September 26, 2019
Publication date:
July 1, 2021
Applicants:
LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY