Patents Assigned to MUSASHINO UNIVERSITY
  • Patent number: 12098129
    Abstract: To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts and suppresses lung fibrosis without injuring alvocar epithelial cells. A pharmaceutical composition for treating fibrosis, the pharmaceutical composition comprising a compound of formula (I) or formula (II): wherein in formula (I), R1 represents a C1-4 alkyl group optionally substituted with a halogen atom, and l represents an integer of 3 to 6; and in formula (II), n represents an integer of 8 to 12, or a pharmaceutically acceptable salt thereof or a solvate of the compound or the salt thereof.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: September 24, 2024
    Assignees: LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY
    Inventors: Tohru Mizushima, Ken-ichiro Tanaka
  • Publication number: 20240261375
    Abstract: A pharmaceutical composition including a lecithinized superoxide dismutase, for treating or preventing a disorder associated with administration of an anticancer agent. A method for treating or preventing a disorder associated with administration of an anticancer agent, including administering a lecithinized superoxide dismutase to a subject in need thereof. The disorder associated with administration of an anticancer agent is a disorder selected from a neurological disorder, a liver disorder, drug-induced deafness, a kidney disorder, myelosuppression, and a combination of one or more thereof.
    Type: Application
    Filed: May 17, 2022
    Publication date: August 8, 2024
    Applicants: LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY
    Inventors: Zhiwei QIAO, Manami HONDA, Shouta AKIMOTO, Tomoki SASAKI, Noriko KAJI, Koichiro FUKUDA, Tohru MIZUSHIMA, Ken-ichiro TANAKA
  • Publication number: 20210198199
    Abstract: To provide a novel therapeutic agent for fibrosis that induces selective cell death of lung fibroblasts and suppresses lung fibrosis without injuring alvocar epithelial cells. A pharmaceutical composition for treating fibrosis, the pharmaceutical composition comprising a compound of formula (I) or formula (II): wherein in formula (I), R1 represents a C1-4 alkyl group optionally substituted with a halogen atom, and l represents an integer of 3 to 6; and in formula (II), n represents an integer of 8 to 12, or a pharmaceutically acceptable salt thereof or a solvate of the compound or the salt thereof.
    Type: Application
    Filed: September 26, 2019
    Publication date: July 1, 2021
    Applicants: LTT BIO-PHARMA CO., LTD., MUSASHINO UNIVERSITY
    Inventors: Tohru MIZUSHIMA, Ken-ichiro TANAKA