Patents Assigned to Mycobics B.V.
  • Antibiotics and Methods For Producing Them
    Publication number: 20100292137
    Abstract: The invention relates to cyclic peptides and methods for producing and using them. Provided is amongst others a method for determining whether a compound comprises antibiotic activity, the method comprising providing a cyclic peptide to a bacterium wherein a 23S rRNA in a 5OS ribosomal subunit does not comprises a 2? O-methylation at a nucleotide that corresponds to nucleotide C 1920 in E. coli and determining whether said compound inhibits growth of said first bacterium.
    Type: Application
    Filed: January 19, 2007
    Publication date: November 18, 2010
    Applicant: Mycobics B.V.
    Inventors: Stephen Roger Douthwaite, Shanna Koltzen Johansen, Gilles Philippus Van Wezel