Abstract: The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided.

Abstract: Various examples are directed to computer-implemented systems and methods for graphical representation of financial account outflow. The method includes obtaining, by a processor of a computer, a transaction of an account holder including an amount and frequency of the transaction, and categorizing the transaction on a continuum of discretionary spending and fixed expense spending. The transaction is displayed by the processor on a user interface using a graph having an x-axis providing a frequency of the at least one transaction, and a y-axis indicating the categorization of the transaction. The transaction is displayed as a bubble on the graph, where the bubble has a diameter that is proportional to the amount of the transaction.

Abstract: A cardio-pulmonary compression system includes a compression device (110), a supporting mechanism (120) coupled to the compression device and a feedback sensor (104) configured to measure interactions between a patient and the compression device. A control unit (112) is configured to receive input from the feedback sensor and adjust operating parameters of the compression system to meet a target parameter during operation of the compression device.

Abstract: A markerless robot tracking system (10) employing a surgical RCM robot (20) including a primary revolute joint (22) rotatable about a primary rotational axis and a secondary revolute joint (22) rotatable about a secondary rotational axis. A plurality of unique landmark sets are integrated into the robot (20) with each unique landmark set including landmark(s) (30) in a fixed orientation relative to the primary rotational axis and further including additional landmark(s) (30) in a fixed orientation relative to the secondary rotational axis. The system (10) further an optical camera (41, 51) for visualizing a subset of the plurality of unique landmark sets within a camera coordinate system (43, 53), and a robot tracking controller (70) for estimating a robot pose of the surgical RCM robot (20) within the camera coordinate system (43, 53) derived from the visualization by the optical camera (41, 51) of the subset of landmark(s) within the camera coordinate system (43, 53).

Abstract: Systems and methods for preparing customer check deposit requests with a mobile device and a reflective surface are described. A check frame is positioned between a customer mobile device with a built-in camera and a mirror such that, when a check is placed in the check frame, the camera can view both sides of the check simultaneously. The camera can take a single picture that includes both sides of the check, process it, and submit it as a check deposit request to the customer's financial institution.

Abstract: The present invention relates to patient interfaces optically indicating a user that a member of the patient interface needs to be replaced due to wear. In particular, the present invention relates to a member for patient interface which includes at least one functional material having a predefined functionality and at least one indicator wherein the concentration of the at least one indicator in the member correlates with the predefined functionality of the at least one functional material.

Abstract: A minimal weight patient interface device that delivers breathing gas to a user includes a cushion assembling including a support cushion assembly and a sealing member is described herein. In one exemplary embodiment, the support cushion assembly includes a wedge that is made of a high density foam received within a wedge receiving portion of the support cushion assembly. In the exemplary embodiment, the cushion assembly is formed by the sealing member fitting over the support cushion assembly. The sealing member, in one embodiment, is made of silicone, for example, having a low durometer value (e.g., between 5-10 Shore 00). Furthermore, in one embodiment, the patient interface device also includes a faceplate that is placed over the cushion assembly and is made of a thermoform, such as a high density foam laminated between two pieces of fabric, such as polyester.

Abstract: A method for encouraging saving towards a financial goal for an individual includes receiving on an electronic computing device one or more personal media elements from the individual. A receipt from a purchase by the individual is received. The receipt includes information relating to the purchase made by the individual. Information from the receipt relative to the financial goal is analyzed. At least one of the one or more personal media elements is selected for presentation with the receipt. The at least one of the one or more personal media elements selected is related to an effect of the purchase on achieving the financial goal.

Abstract: Disclosed in some examples are methods, systems, and machine readable mediums for providing P2P lending through mobile wallets. The P2P lending may utilize a central registry or be a fully distributed P2P system. In some examples, the use of a network accessible P2P loan service may simplify the discovery and communication with other mobile wallets throughout the process of obtaining a loan.

Abstract: The invention relates to a device (10) for determining spatially dependent x-ray flux degradation and photon spectral change, a system (1) for determining spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a method for spatially dependent x-ray flux degradation and photon spectral change for an x-ray tube (20), a computer program element for controlling such device (10) or system (1) for performing such method and a computer readable medium having stored such computer program element. The device (10) for determining spatially dependent x-ray flux degradation and photon spectral change comprises an acquisition unit (11), a processing unit (12), a calculation unit (13), and a combination unit (14). The acquisition unit (11) is configured to acquire x-ray flux degradation data for the x-ray tube (20). The processing unit (12) is configured to process the x-ray flux degradation data into spatially dependent flux degradation data.

Abstract: Systems and methods for multifactor physical authentication are disclosed. In one embodiment, a method for accessing an entitlement at a facility using multifactor physical authentication may include (1) receiving, at a first electronic interface at a facility, an individual identifier from an individual; (2) at least one computer processor presenting a challenge to the individual; (3) the at least one computer processor receiving, at a second interface, a response to the challenge; (4) the at least one computer processor authenticating the individual based on the individual identifier and the response; (5) the at least one computer processor retrieving at least one authorized entitlement associated with the individual identifier; and (6) the at least one computer processor activating the entitlement at the facility associated with the authorized entitlement.

Abstract: An implement for automatically milking a dairy animal, such as a cow, comprises a milking parlour, a sensor for observing a teat, and a milking robot for automatically attaching a teat cup to the teat. The milking robot comprises a robot control that is connected to the sensor. The sensor comprises a radiation source for emitting light, a receiver for receiving electromagnetic radiation reflected from the dairy animal, a lens, and sensor control unit. The sensor comprises a matrix with a plurality of rows and a plurality of columns of receivers. The sensor control unit is designed to determine for each of the receivers a phase difference between the emitted and the reflected electromagnetic radiation in order to calculate the distance from the sensor to a plurality of points on the part to be observed of the dairy animal.

Abstract: An animated 3D image multiplying light assembly includes a light source having a plurality of light-emitting diodes. A mask is disposed at a predetermined distance from the light source, and a plurality of holes are adapted to allow light to pass through the mask. The mask includes more holes than the number of light-emitting diodes. A first lenticular sheet is adjacent a second lenticular sheet for projecting light from the light source having passed through the mask. The first lenticular sheet is aligned perpendicular with the second lenticular sheet for homogenizing light in a first direction and a second direction, perpendicular to the first direction. An outer lens is positioned such that light projected from the first lenticular sheet and the second lenticular sheet appears as though positioned at different depths with respect to the outer lens, providing a 3D appearance. When viewed dynamically, the light projected appears to move.

Abstract: An artificial hair comprises a mesh layer configured to fit around a circumference of a user's head comprising an inner surface, an outer surface, a front region, a rear region, and a circumferential edge region that extends around the front region and the rear region; a filament coupled to the outer surface of the mesh layer, at least a portion of the filament being disposed in each of the front region, the rear region and on the circumferential edge region of the mesh layer; a plurality of first hair members coupled to the filament; and a plurality of second hair members slidably disposed between the filament and the mesh layer, the first hair members comprising a first length and the second hair members comprising a second length, the first length being greater than the second length.

Abstract: A method (400) for controlling a proportional valve. The method includes the steps of: (i) providing (410) a proportional flow valve system that includes: a closed loop flow controller (110) including a proportional flow control valve (140), a flow sensor (150), and an adjustable gain (180); and an adaptive controller (120) including a model (160) of the closed loop flow controller, and a gain control (170); (ii) actuating (420) the proportional flow control valve; (iii) measuring (430) actual gas flow; (iv) determining (440) a difference between the measured gas flow rate and a desired gas flow rate; (v) adjusting (450) the proportional flow valve using the determined difference; (vi) initiating (460) a response from the model of the closed loop flow controller; (vii) determining (470) a gain for the closed loop flow controller; and (viii) adjusting (480) the adjustable gain of the closed loop flow controller.

Abstract: A magnetic resonance (MR) system includes a main magnet having a bore and producing a substantially homogenous magnetic field (B0) within a scanning volume. A mobile radio-frequency (RF) coil (MRF) includes at least one transmit antenna for transmitting a location signal within the bore of the magnet. At least one receive antenna os situated substantially at a known location and configured to receive the transmitted location signal. A controller is configured to align the transmit antenna of the MRF with reference to the known location of the receive antenna based upon an analysis of the received location signal.

Abstract: An embodiment of the present invention is directed to an automated archiving tool. A system that implements an automated archiving tool comprises: a memory component; an interactive interface that receives one or more user inputs; and a processor, coupled to the memory component and the interactive interface, the processor configured to perform the steps comprising: querying for issues that meet an archive criteria; performing an export of the queried issues that meet the archive criteria; executing a script creating a macro for tickets and associated attachments; archiving the tickets as flat files; executing a script to index the archived issues by project; moving support files to a common directory; macro archiving the attachments; and identifying local references.

Abstract: A grooming appliance (100) comprising: a grooming mechanism (102) for grooming a user; a motor (104) arranged to operate the grooming mechanism; and a controller (106) configured to modulate a data signal into sound produced by the grooming appliance during the operation of the grooming mechanism by the motor, in order to transmit information relating to the grooming appliance. In embodiments, the sound being modulated is caused by the motor when operating the grooming mechanism. In this case the controller is arranged to supply a drive signal to the motor in order to control the motor, and to perform the modulation by varying the drive signal in order to modulate the data signal into the sound caused by the motor during operation of the grooming mechanism.

Abstract: An illumination system for a metrology apparatus that can achieve illumination spatial profile flexibility, high polarization extinction ratio, and high contrast. The illumination system includes a polarizing beam splitter (PBS), an illumination mode selector (IMS), and a reflective spatial light modulator (SLM). The PBS divides an illumination beam into sub-beams. The IMS has a plurality of apertures that transmits at least one sub-beam and may be arranged in multiple illumination positions corresponding to illumination modes. A pixel array of the reflective SLM and reflects a portion of the sub-beam transmitted by the IMS back to the IMS and PBS. The PBS, IMS, SLM collectively generates a complex amplitude or intensity spatial profile of the transmitted sub-beam.

Abstract: A method performed by a processor of a financial institution computing system includes allowing an account holder at the financial institution to initiate a transaction with the financial institution remotely (e.g., via smartphone app, online banking portal, etc.), by submitting a request for a branch of the financial institution to provide the specified transaction to the account holder's vehicle upon arrival of the account holder. The pickup and completion of the account holder requested transaction occurs in a designated spot near the financial institution's branch location and from the convenience of the account holder's vehicle. The curbside service alleviates the uncertainty and fluctuating time cost to engage in transactions at a branch of a financial institution by providing an account holder with a user interface to make a transaction request that will be ready to complete when the account holder arrives at the chosen time.