Patents Assigned to N.V. Nutricia
  • Publication number: 20190175622
    Abstract: The invention pertains to the use of therapeutically effective amounts of (i) vitamin A and/or functional equivalents, (ii) vitamin D and/or functional equivalents, and (iii) at least one omega-3 PUFA, preferably DHA and/or EPA, more preferably DHA and EPA, for the manufacture of a composition or medicament for treating, reducing and/or preventing neuroinflammation and/or symptoms associated with neuroinflammation in a subject in need thereof, as well as for reducing microglia activation, and/or for treating, reducing and/or preventing symptoms associated with excessive activation of microglia; and/or for reducing the secretion of inflammatory cytokines, preferably IL-6, and/or for treating, reducing and/or preventing symptoms associated with excessive secretion of inflammatory cytokines, in a subject in need thereof.
    Type: Application
    Filed: June 9, 2017
    Publication date: June 13, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Sofia LOPES DA SILVA, Ladislaus Maria BROERSEN, Robert Johan Joseph HAGEMAN, Jan Maarten VERKUIJL
  • Publication number: 20190166864
    Abstract: The invention pertains to a process for simultaneous producing an infant formula product and a dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream by a combination of microfiltration and ultrafiltration, wherein the casein stream originates from the microfiltration as retentate, the whey protein stream originates from the ultrafiltration as retentate and the lactose stream originates from the ultrafiltration as permeate; (b) combining at least part of the whey protein stream originating from step (a) and a lactose source to obtain are combined stream; (c) using the recombined stream originating from step (b) in the manufacture of the infant formula product; and (d) using at least part of the casein stream originating from step (a) and defatted animal milk in the manufacture of the dairy product.
    Type: Application
    Filed: August 8, 2017
    Publication date: June 6, 2019
    Applicants: COMPAGNIE GERVAIS DANONE, N.V. NUTRICIA
    Inventors: Franck DAVID, Claire QUEGUINER, Laurent SCHMITT, Gerrit HOLS, John TOBIN, Raoul Charles Johan MOONEN
  • Patent number: 10306909
    Abstract: The present invention is based on the finding that free amino acids can both negatively or positively influence overall taste of free amino acid-based enteral nutritional compositions, and the amino acids can thus be categorized. A striking balance of both categories of amino acids to arrive at amino acid-based nutritional composition with improved taste, yet not compromising the (regulatory) dietary restrictions on essential amino acids and conditionally essential amino acids.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: June 4, 2019
    Assignee: N.V. NUTRICIA
    Inventors: Jonathan Rason, Carole Springett
  • Publication number: 20190159500
    Abstract: A fermented infant formula or follow on formula for promoting a growth trajectory more similar to the growth trajectory in breast-fed infants. A fermented infant formula or follow on formula for i) promoting a balanced growth trajectory or body development in an infant and/or ii) preventing or reducing the risk of an unbalanced growth trajectory or body development in an infant. Saud formula comprises 3 to 7 g lipid/100 kcal, 1.25 to 5 g protein/100 kcal and 6 to 18 g digestible carbohydrate/100 kcal and wherein the nutritional composition comprises an ingredient fermented by lactic acid producing bacteria, and 0.05 to 1.5 wt % lactic acid based on dry weight.
    Type: Application
    Filed: May 10, 2017
    Publication date: May 30, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Houkje BOURITIUS, Marieke ABRAHAMSE-BERKEVELD
  • Publication number: 20190159472
    Abstract: The invention pertains to a process for simultaneous producing an infant formula product and an acidic dairy product from defatted animal milk, comprising (a) processing the milk into a casein stream, a whey protein stream and a lactose stream, by: (i) subjecting the defatted animal milk to a filtration step over a microfiltration membrane capable of retaining bacteria and permeating milk proteins, to provide a debacterialized milk as permeate; (ii) subjecting the permeate originating from step (i) to a filtration step over a microfiltration membrane capable of retaining casein and permeating whey proteins, to provide a casein stream as retentate and a permeate comprising whey protein; (iii) fractionating the permeate originating from step (ii) into a whey protein stream and a lactose stream; (b) combining part of the casein stream, at least part of the whey protein stream originating from step (a) and a lactose source to obtain a recombined stream, wherein the lactose source comprises acid whey; (c) using th
    Type: Application
    Filed: August 8, 2017
    Publication date: May 30, 2019
    Applicants: COMPAGNIE GERVAIS DANONE, N.V. NUTRICIA
    Inventors: Franck DAVID, Claire QUEGUINER, Laurent SCHMITT, Gerrit HOLS, John TOBIN, Raoul Charles Johan MOONEN, Evelien Louise VAN EIJK-VAN BOXTEL, Evan ABRAHAMSE
  • Publication number: 20190151343
    Abstract: The invention pertains to the use of therapeutically effective amounts of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof, (ii) docosahexaenoic acid (22:6; DHA), and/or eicosapentaenoic acid (20:5; EPA), or esters thereof, and (iii) choline, or salts or esters thereof, in the manufacture of a product for therapeutically improving language development and reducing language skills impairment in children with suspected or confirmed cerebral palsy, or children at risk thereof.
    Type: Application
    Filed: April 4, 2016
    Publication date: May 23, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Arjen Paul VOS, Danielle Stefanie COUNOTTE, Ana Renée Pascale SMORENBURG
  • Publication number: 20190151273
    Abstract: The invention pertains to the use of therapeutically effective amounts of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof, (ii) docosahexaenoic acid (22:6; DHA), and/or eicosapentaenoic acid (20:5; EPA), or esters thereof, (iii) choline, or salts or esters thereof, in the manufacture of a product for therapeutically treating or preventing global developmental delay or reducing the risk symptoms such as cognitive impairment associated therewith in a child.
    Type: Application
    Filed: April 4, 2016
    Publication date: May 23, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Ruurd VAN ELBURG, Arjen Paul VOS, Danielle Stefanie COUNOTTE, Ana Renée Pascale SMORENBURG
  • Publication number: 20190142048
    Abstract: The invention relates to a method for preparing a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, comprising a high amount of micellar casein, comprising dissolving a dry blend of micellar casein and digestible carbohydrate.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Applicant: N.V. Nutricia
    Inventors: Jan Michel VENEMAN, Hilde RUIS, Suzanne VAN STEENIS
  • Publication number: 20190142052
    Abstract: A fermented infant formula for promoting improved eating behaviour and reducing the risk of obesity. The formula comprises 3 to 7 g lipid/100 kcal, 1.25 to 5 g protein/100 kcal and 6 to 18 g digestible carbohydrate/100 kcal and wherein the nutritional composition comprises an ingredient fermented by lactic acid producing bacteria, and 0.05 to 1.5 wt % lactic acid based on dry weight.
    Type: Application
    Filed: May 10, 2017
    Publication date: May 16, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Carolus Maria Johannes Leonardus VEREIJKEN, Houkje BOURITIUS
  • Patent number: 10285427
    Abstract: The invention relates to thickening compositions for thickening nutritional products to make the nutritional product suitable for consumption by dysphagia patients, said thickening composition comprising starch, xanthum gum and/or methylcellulose and galactomannan and/or glucomannan.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: May 14, 2019
    Assignee: N.V. Nutricia
    Inventor: Edward Lucian Sliwinski
  • Publication number: 20190133172
    Abstract: A method to predict the risk of eczema is provided based on differences in the development of microbiota and its metabolites in healthy infants and infants that develop eczema, and nutritional remedies based on this finding, in the form of lactate utilizing bacteria and fibres stimulating lactate utilizing bacteria.
    Type: Application
    Filed: June 12, 2017
    Publication date: May 9, 2019
    Applicant: N.V. NUTRICIA
    Inventors: Harm Johannes WOPEREIS, Jan KNOL
  • Patent number: 10264806
    Abstract: Medical dairy products are highly concentrated in proteins and minerals. Formulation of such products is challenging, since viscosities can easily increase during processing and storage. It was found that using one or more chelating agents selected from the group consisting of a phosphoric acid, citric acid, a soluble phosphate salt, a soluble citrate salt, or a mixture thereof, the viscosity and the transparency of an aqueous micellar casein composition, comprising 6 to 20 g/100 ml of micellar casein and having a pH of about 6 to 8 could be controlled independently of each other. It was found that products become more viscous after addition of phytate, citrate, or orthophosphate, and that the viscosity depends on concentration and type of phosphate. Addition of hexametaphosphate leads to gel formation. In contrast, high concentrations of uridine monophosphate can be added without significantly affecting the viscosity.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: April 23, 2019
    Assignee: N.V. NUTRICIA
    Inventors: Esther Jacqueline De Kort, Marcel Minor
  • Publication number: 20190076375
    Abstract: The invention pertains to the use of therapeutically effective amounts of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; and(ii) at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof; and (iii) vitamin C and/or selenium, optionally in combination with vitamin E, in the manufacture of a product for therapeutically preventing and/or slowing down brain atrophy in a human subject in need thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: March 14, 2019
    Applicant: N.V. NUTRICIA
    Inventor: Mattheus Cornelis DE WILDE
  • Publication number: 20190076490
    Abstract: The invention relates to nutritional compositions with Bifidobacterium breve and non-digestible oligosaccharides for use infants or toddlers for use in improving cognitive or behavioral performance or neuroinflammation.
    Type: Application
    Filed: May 2, 2018
    Publication date: March 14, 2019
    Applicant: N.V. Nutricia
    Inventors: Johan GARSSEN, Ruurd VAN ELBURG, Nana BARTKE, Aletta Desiree KRANEVELD
  • Publication number: 20190070126
    Abstract: The invention pertains to the use of therapeutically effective amounts of (a) (i) vitamin C and/or selenium and (ii) at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof; or (b) (i) vitamin C and/or selenium and (iii) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; or (c) a combination of (i), (ii) and (iii); wherein (a), (b) or (c) optionally further comprises vitamin E, in the manufacture of a product for therapeutically improving synaptic connectivity and/or therapeutically supporting memory and/or cognitive function in a human subject in need thereof.
    Type: Application
    Filed: March 8, 2017
    Publication date: March 7, 2019
    Applicant: N.V. NUTRICIA
    Inventor: Mattheus Cornelis DE WILDE
  • Patent number: 10219534
    Abstract: The invention relates to a method for preparing a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, comprising a high amount of micellar casein, comprising dissolving a dry blend of micellar casein and digestible carbohydrate.
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: March 5, 2019
    Assignee: N.V. NUTRICIA
    Inventors: Jan Michel Veneman, Hilde Ruis, Suzanne Van Steenis
  • Patent number: 10201250
    Abstract: A container assembly includes a thermoformed tub of relatively thin plastic material having a peripheral wall extending to an upper edge and defining a product containing space. A lower rim is connected to the upper edge of the tub, the lower rim defining an opening giving access to the product containing space and being formed of a relatively thicker plastic material. An upper rim is connectable to the lower rim and a lid is provided for selectively closing the opening. By the use of a thin walled thermoformed tub, the amount of material required for forming the body of the container is limited. Furthermore, the lower rim of relatively thicker plastic material provides the required support to the relatively thin material of the peripheral wall, allowing effective connection to the upper rim.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: February 12, 2019
    Assignee: N.V. Nutricia
    Inventors: Alexander Josephus Maricus Van Puijenbroek, Sjors Floris Crusius, Priya Caroline Roberts, Benoit Marie Francois Piette, Patrick Michael Van Baal, Franck Perek
  • Patent number: 10166252
    Abstract: The invention pertains to the use of a preparation for the manufacture of a composition for preventing or treating impaired plasma levels of one or more polar lipids such as phosphatidylcholines [PC] selected from the group consisting of phosphatidylcholine diacyl C36:6 [PC aa C36:6], phosphatidylcholine diacyl C38:0 [PC aa C38:0], phosphatidylcholine diacyl C38:6 [PC aa C38:6], phosphatidylcholine diacyl C40:6 [PC aa C40:6] and phosphatidylcholine acyl-alkyl C40:6 [PC ae C40:6] in a preclinical AD or MCI subject or a subject with a high likelihood of developing AD or MCI, and wherein said subject is administered with a composition comprising at least one, preferably at least two, most preferably all B vitamins selected from the group consisting of vitamin B6, vitamin B12 and vitamin B9.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: January 1, 2019
    Assignee: N.V. NUTRICIA
    Inventor: Nick Van Wijk
  • Publication number: 20180360393
    Abstract: The invention provides a system (100a) for tracking infant development, the system comprising: —a portable device (101) including a camera and a processing unit, and —a weighing scale (102), preferably comprising a wireless transceiver; wherein the weighing scale is configured to measure the weight of an infant and to transmit the measured weight information to the portable device; and wherein the portable device is configured to —capture (401) an image of the infant; —combine the received weight information and information derived from the image of the infant to obtain (404) infant development statistics; and —store (403) the image and the obtained infant development statistics in a storage; wherein the information derived from the image includes at least one of the height of the infant and the head circumference of the infant. The invention further provides a portable device, a weighing scale, and a computer readable medium.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 20, 2018
    Applicant: N.V. NUTRICIA
    Inventor: Elzemiek Beatrix Maria VAN BERKEL-WIJNEN
  • Patent number: 10136668
    Abstract: The present invention concerns an improved balance of the essential branched chain amino acids leucine, isoleucine and valine in infant formula.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: November 27, 2018
    Assignee: N.V. Nutricia
    Inventors: Johannes Bernard Van Goudoever, Eline Marleen Van Der Beek, Marieke Abrahamse-Berkeveld, Günther Boehm