Patents Assigned to N.V. Nutricia
  • Publication number: 20250089752
    Abstract: The invention pertains to a composition for use in increasing the relative abundance of Bacteroides and Parabacteroides in the intestinal microbiota of an infant that was delivered by Caesarean section or of an infant that was exposed to antibiotics early in life (e.g. intrapartum antibiotic prophylaxis (IAP)), preferably an infant that was delivered by Caesarean section, wherein the composition comprises Bifidobacterium breve and non-digestible oligosaccharide(s).
    Type: Application
    Filed: November 11, 2024
    Publication date: March 20, 2025
    Applicants: N.V. Nutricia, Nutricia Early Life Nutrition (Shanghai) Co., Ltd.
    Inventors: Harm Johannes Wopereis, Guus Roeselers, Mengjin Liu, Yi Jin
  • Patent number: 12245992
    Abstract: The invention pertains to the use of therapeutically effective amounts of (a) (i) vitamin C and/or selenium and (ii) at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof; or (b) (i) vitamin C and/or selenium and (iii) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; or (c) a combination of (i), (ii) and (iii); wherein (a), (b) or (c) optionally further comprises vitamin E, in the manufacture of a product for therapeutically improving synaptic connectivity and/or therapeutically supporting memory and/or cognitive function in a human subject in need thereof.
    Type: Grant
    Filed: January 23, 2024
    Date of Patent: March 11, 2025
    Assignee: N.V. Nutricia
    Inventor: Mattheus Cornelis de Wilde
  • Patent number: 12239649
    Abstract: The present invention concerns a composition comprising dietary fiber for use in the dietary management of methylmalonic acidemia (MMA) and/or propionic acidemia (PA), and/or for use in treating and/or reducing MMA and/or PA, and/or treating, reducing and/or preventing symptoms associated therewith.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: March 4, 2025
    Assignee: N.V. Nutricia
    Inventors: Mirjam Kuhn, Maryam Rakhshandehroo
  • Patent number: 12233039
    Abstract: The invention thus pertains to the use of a composition comprising: (a) uridine or uridine phosphate; and (b) docosahexaenoic acid and/or eicosapentaenoic acid, for improving memory and/or the treatment or prevention of impaired memory function, in a subject with a mini-mental state examination of 24-26, wherein said composition is enterally administered to the subject. In the MMSE test, any score of 27 or higher (out of 30) is effectively normal. In the patients with dementia, 20-26 indicates mild dementia, 10-19 moderate dementia, and below 10 severe dementia. It was the present inventors' belief that within the group of 20-26, the memory impairment in the sub-group of 24-26 may even be reversible, as the pathological pathways have just started to develop. In this group of subjects the pathological pathways have just started to develop. Clinical studies show excellent results for this subgroup.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: February 25, 2025
    Assignee: N.V. Nutricia
    Inventors: Patrick Joseph Gerardus Hendrikus Kamphuis, Martine Groenendijk, Anke Bongers
  • Publication number: 20250033846
    Abstract: A card based container has a tubular sidewall of laminate material and first and second end closures, sealed to the tubular sidewall to form a hermetically sealed package. The sidewall has an outer card layer, an inner hygienic layer and one or more sealing strips provided at an inner surface of the inner hygienic layer, located at connection locations where the sidewall seals to itself or to the respective end closures. The sealing strips include a heat-sealable polymer. The overall amount of non-paper content in the sidewall and in the package may thus be reduced.
    Type: Application
    Filed: September 4, 2024
    Publication date: January 30, 2025
    Applicant: N.V. NUTRICIA
    Inventor: Franck PEREK
  • Publication number: 20250017881
    Abstract: The invention relates to a first composition providing at least one of acetic acid or butyric acid for controlling ketosis associated with a ketogenic diet in a subject adhering to a ketogenic diet, wherein controlling ketosis involves a) administering the first composition, b) optionally administering a second composition comprising propionic acid to reduce ketone production/administering a second composition comprising propionic acid provided that blood ketone levels are above 3 mmol/L.
    Type: Application
    Filed: August 27, 2024
    Publication date: January 16, 2025
    Applicant: N.V. Nutricia
    Inventors: Jose Pablo Silva, Hester Meeusen, Lotte Hendrika Johanna Dopheide, Sebastian Tims
  • Publication number: 20250017252
    Abstract: The invention relates to at least one of C4 or C6 fatty acids and optionally C2 fatty acids for enhancing ketosis associated with a ketogenic diet and/or preventing and/or treating resistance to a ketogenic diet, in a subject adhering to a ketogenic diet, wherein the at least one of C4 or C6 fatty acids and optionally C2 fatty acids are comprised in a non-ketogenic ketogenic diet-booster composition, or the at least C4 or C6 fatty acids and optionally C2 fatty acids are provided in non-ketogenic amounts by a dietary fibre blend comprised in a non-ketogenic ketogenic diet-booster composition.
    Type: Application
    Filed: August 28, 2024
    Publication date: January 16, 2025
    Applicant: N.V. Nutricia
    Inventors: Jose Pablo Silva, Hester Meeusen, Lotte Hendrika Johanna Dopheide, Sebastian Tims
  • Publication number: 20250017973
    Abstract: Provided herein is a nutritional composition having therapeutically effective amounts of a combination of (a) hydrolysed whey protein and (b) MCT for use in (i) reducing tumor growth and/or (ii) for use in improving treatment efficacy in a subject having cancer and undergoing cancer treatment.
    Type: Application
    Filed: September 12, 2024
    Publication date: January 16, 2025
    Applicant: N.V. Nutricia
    Inventors: Bram Jeroen van Bergenhenegouwen, Bram Dorresteijn, Hannah Rose Wardill
  • Publication number: 20250014758
    Abstract: The invention provides a method, system, and computer program product for determining a maturation state of an infant aged between 0 and 120 months, comprising measuring at least one microbial biomarker from a set of measurable microbial biomarkers from a faecal sample of the infant, determining a predicted age of the infant based on the at least one microbial biomarker, wherein the at least one microbial biomarker is selected from the set of measurable microbial biomarkers based on an analysis of the set of measurable microbial biomarkers as measured in faecal samples from a plurality of vaginally-born breast-fed infants at a plurality of ages, the predicted age is obtained based on an evaluation of the at least one measured microbial biomarker using a function based on a plurality of corresponding at least one biomarkers measured in the faecal samples from the plurality of vaginally-born breast-fed infants at the plurality of ages.
    Type: Application
    Filed: September 4, 2024
    Publication date: January 9, 2025
    Applicant: N.V. Nutricia
    Inventors: Francisco Manuel Codoñer Cortes, Johanna Maria Lambert, Guus Roeselers
  • Publication number: 20240415793
    Abstract: The invention relates to a neuroprotective composition comprising therapeutically effective amounts of a combination of pyruvate and citrate, for the treatment and/or prevention of neuronal damage in a subject suffering from or at risk of seizures.
    Type: Application
    Filed: August 27, 2024
    Publication date: December 19, 2024
    Applicant: N.V. Nutricia
    Inventors: Jose Pablo Silva, Hester Meeusen
  • Publication number: 20240415162
    Abstract: The present invention relates to a fermented infant or follow on formula comprising non digestible oligosaccharides for decreasing duration of crying, reducing crying episodes, and incidence of colics in infants.
    Type: Application
    Filed: August 26, 2024
    Publication date: December 19, 2024
    Applicant: N.V. Nutricia
    Inventors: Thomas LUDWIG, Houkje BOURITIUS, Donghui YU
  • Publication number: 20240412872
    Abstract: The invention provides a method of analysing the consistency of stool, including the steps of: providing stool of an infant, capturing, with a portable device comprising a camera, an image of the stool, providing the captured image to an input layer of a pre-trained convolutional neural network, CNN, processing the captured image using the CNN to obtain, from a final layer of the CNN, a classification vector and to obtain information about a predicted score from the classification vector, wherein at least the final layer of the CNN has been customized so that each element of the classification vector corresponds to a score of a stool analysis scale, and storing information about the predicted store.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 12, 2024
    Applicant: N.V. Nutricia
    Inventors: Damien Luc Dominique Marie Paineau, Agathe Camille Foussat, Thomas Ludwig, Inès Oukid
  • Publication number: 20240324644
    Abstract: A consortium of specific probiotic bacteria comprising Bifidobacterium bifidum and Bifidobacterium breve with specific carbohydrate degrading properties, specific human milk oligosaccharide and preferably also beta-galacto-oligosaccharides with a higher degree of polymerization, is particularly effective for improving intestinal microbiota resilience.
    Type: Application
    Filed: June 13, 2024
    Publication date: October 3, 2024
    Applicant: N.V. Nutricia
    Inventors: Cornelus Johannes Petrus van Limpt, Kaouther Ben Amor, Jan Knol, Ana Maria GIL RODRÍGUEZ
  • Publication number: 20240316088
    Abstract: The invention pertains to a solid composition suitable for treating adult animals that suffer from brain-related disorders, brain-related decline or brain-related diseases, preferably suitable for treating adult animals that suffer from brain-related disorders, the composition containing (i) a uridine source, wherein the amount of the sum of all uridine sources, calculated on the basis of the weight of the molar equivalent of uridine monophosphate (UMP), is 0.3-15 g per 100 g dry weight of the composition, (ii) a polyunsaturated fatty acid, preferably an omega-3 polyunsaturated fatty acid, (iii) choline bitartrate, (iv) a buffering salt component, and (v) a milk protein source, wherein the milk protein source is a milk powder, and the buffering salt component containing at least one food approved salt, with a buffering capacity between pH 5-8, the buffering salt component preferably containing a mixture of food-approved salts, or a food-approved salt and its conjugated acid or base.
    Type: Application
    Filed: March 12, 2024
    Publication date: September 26, 2024
    Applicant: N.V. Nutricia
    Inventors: Leo Samuel Payne, Gerrit Hols, Danielle Stefanie Counotte, Sarah Glyn-Jones
  • Patent number: 12089611
    Abstract: The present invention relates to a two-step emulsification process for preparing a lipid and protein component-containing composition comprising large lipid globules, preferably coated with polar lipids, and to the compositions obtained thereby. Optionally, the lipid and protein component-containing composition is spray-dried. The obtained compositions are for feeding infants and young children.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: September 17, 2024
    Assignee: N. V. NUTRICIA
    Inventors: Koen Cornelis Van Dijke, Jewe Schröder, Memet Ali Ustunel, Daniël Georg Reinhold Halsema, Raoul Charles Johan Moonen
  • Publication number: 20240299490
    Abstract: The invention pertains to a liquid nutritional composition for use in prevention and/or treatment of whole body protein metabolism decline or whole body protein function decline, or for improving whole body protein metabolism or whole body protein function, particularly for use in muscle decline, or for improving muscle function, in a human subject suffering from metabolic stress and/or starvation, wherein the human subject is preferably a human elderly subject of at least 50 years of age, wherein the composition comprises a protein fraction comprising (a) 15 to 35 weight % of casein; (b) 25 to 50 weight % of whey protein; (c) 10 to 30 weight % of soy protein; and (d) 10 to 30 weight % of pea protein; relative to the total protein in the protein fraction, wherein the sum of said proteins preferably equals 100 weight % of the protein fraction.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 12, 2024
    Applicant: N.V. Nutricia
    Inventors: Miriam Van Dijk-Ottens, Francina Jeanette Dijk, Matthew James Walter Furber
  • Publication number: 20240303848
    Abstract: Electronic device for estimating a height of a human, the electronic device comprising: a processor configured to: obtain an image including at least a part of a representation of the human and reference information; input the image to a first neural network and obtain as output from the first neural network first information, the first information related to a plurality of keypoints in the body of the human; input the image to a second neural network and obtain as output from the second neural network second information, the second information related to the reference information; and estimate the height of the human based on the first information and the second information; and an output unit configured to output the estimated height.
    Type: Application
    Filed: March 18, 2024
    Publication date: September 12, 2024
    Applicant: N.V. Nutricia
    Inventors: Agathe Camille Foussat, Reyhan Suryaditama, Meenakshisundaram Palaniappan, Ruben Zado Hekster, Laurens Alexander Drapers
  • Publication number: 20240285688
    Abstract: The invention concerns a process for preparing an ultrafiltered whey protein hydrolysate comprising tolerogenic peptides wherein an emulsifier and/or a chaotropic agent is added before ultrafiltration. The invention further concerns the product obtainable by the process.
    Type: Application
    Filed: November 7, 2019
    Publication date: August 29, 2024
    Applicant: N.V. Nutricia
    Inventors: Sérgio Bernardo Castro de Oliveira, Vaida Urbonaite-Zuke, Clémentine Julie Mélanie Dejax, John Mark Anthony Gonsalves, Marko Mank, Bernd Stahl, Aveenash Bala
  • Patent number: 12073944
    Abstract: The invention provides a method of analysing the consistency of stool, including the steps of: providing stool of an infant, capturing, with a portable device comprising a camera, an image of the stool, providing the captured image to an input layer of a pre-trained convolutional neural network, CNN, processing the captured image using the CNN to obtain, from a final layer of the CNN, a classification vector and to obtain information about a predicted score from the classification vector, wherein at least the final layer of the CNN has been customized so that each element of the classification vector corresponds to a score of a stool analysis scale, and storing information about the predicted store.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: August 27, 2024
    Assignee: N.V. Nutricia
    Inventors: Damien Luc Dominique Marie Paineau, Agathe Camille Foussat, Thomas Ludwig, Inès Oukid
  • Publication number: 20240277739
    Abstract: The present invention concerns nutritional compositions for infants and young children that are high in oleic acid and low in palmitic acid and comprise galacto-oligosaccharides, in particular including beta1,3?-galactosyllactose. The nutritional compositions are particularly advantageous for improving intestinal barrier function.
    Type: Application
    Filed: July 1, 2022
    Publication date: August 22, 2024
    Applicant: N.V. Nutricia
    Inventors: Selma Paulien Wiertsema, Saskia Adriana Overbeek, Ingrid Brunhilde Renes, Lauriane Emmanuelle Melanie Schwebel