Abstract: The invention relates to new therapeutic agents against Leishmaniasis.These therapeutic agents consist of submicroscopic particles whose diameter is less than 500 nanometers, the particles being obtained by the micellar polymerization of an alkyl cyanoacrylate in which the alkyl chain contains from 1 to 12 carbon atoms.The therapeutic agents according to the invention may be administered parenterally.
Type:
Grant
Filed:
October 7, 1987
Date of Patent:
July 4, 1989
Assignee:
N.V. Sopar S.A.
Inventors:
Antonio Osuna Carillo de Albornoz, Santiago Castanys
Abstract: Biodegradable particles, with a diameter smaller than 500 nanometers, formed by the micellar polymerization of an alkyl-cyano-acrylate where the term "alkyl" means a lower alkyl radical having 1 to 4 carbon atoms and containing a biologically active substance. Also provided are processes for making pharmaceutical compositions containing the biodegradable particles and using the particles in pharmaceutical and diagnostic applications.
Type:
Grant
Filed:
February 17, 1982
Date of Patent:
December 18, 1984
Assignee:
N.V. Sopar S.A.
Inventors:
Patrick Couvreur, Michel Roland, Peter Speiser