Patents Assigned to N30 PHARMACEUTICALS, INC.
  • Novel Thiophene Inhibitors of S-Nitrosoglutathione Reductase
    Publication number: 20140057957
    Abstract: The present invention is directed to novel thiophene inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: November 5, 2013
    Publication date: February 27, 2014
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventor: Xicheng Sun
  • Pyrrole inhibitors of S-nitrosoglutathione reductase
    Patent number: 8642628
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: February 4, 2014
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Thiophene inhibitors of S-nitrosoglutathione reductase
    Patent number: 8586624
    Abstract: The present invention is directed to novel thiophene inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: November 19, 2013
    Assignee: N30 Pharmaceuticals, Inc.
    Inventor: Xicheng Sun
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20130253024
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: May 24, 2013
    Publication date: September 26, 2013
    Applicant: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Substituted Quinoline Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20130178499
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: October 7, 2011
    Publication date: July 11, 2013
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Chromone inhibitors of S-nitrosoglutathione reductase
    Patent number: 8481590
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: July 9, 2013
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Jan Wasley
  • Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
    Patent number: 8470857
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: June 25, 2013
    Assignee: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Dihydropyrimidin-2(1H)-One Compounds As Neurokinin-3 Receptor Antagonists
    Publication number: 20130131093
    Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: September 24, 2010
    Publication date: May 23, 2013
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Dihydropyridin-2(1H)-One Compounds as S-Nitrosoglutathione Reductase Inhibitors and Neurokinin-3 Receptor Antagonists
    Publication number: 20130096161
    Abstract: The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: July 8, 2011
    Publication date: April 18, 2013
    Applicant: N30 PHARMACEUTICALS, INC.
    Inventors: Xicheng Sun, Jian Qiu