Patents Assigned to Nagasaki University
  • Patent number: 8205534
    Abstract: The present invention provides cutting methods and cutting apparatus that can precisely cut workpieces in complicated shapes with high aspect ratios regardless of materials of the workpieces. The present invention is cutting methods and cutting apparatus using a wire saw wherein cutting processing is performed for a workpiece by extending a cutting wire on a cutting arm that rotates around a wire's center axis or a real cutting position relative to a fixed section and rotating the cutting arm such that a cutting direction of the wire matches a support direction of a total stiffness that supports the wire.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: June 26, 2012
    Assignee: Nagasaki University
    Inventors: Takanori Yazawa, Keiichi Ishikawa, Kou Mineta
  • Patent number: 8192717
    Abstract: A composition for diagnosing amyloid-related diseases, which comprises a flavone derivative, a chalcone derivative, a styrylchromone derivative, or a coumarin derivative, is provided. These compounds have high binding specificity to an amyloid ? protein, high permeability to a blood-brain barrier, and ability to rapidly disappear from sites other than cerebral senile plaque. Accordingly, the composition of the present invention using these compounds enables the diagnosis of amyloid-related diseases with high precision.
    Type: Grant
    Filed: November 25, 2005
    Date of Patent: June 5, 2012
    Assignee: Nagasaki University
    Inventors: Hiroshi Mori, Morio Nakayama, Mamoru Haratake, Masahiro Ono
  • Publication number: 20120100422
    Abstract: This invention provides a nano composite porous electrode material that has high charge-discharge behavior and charge or discharge capacity and a manufacturing method thereof. It also provides a lithium-ion secondary battery using this nano composite porous electrode material. The nano composite porous electrode material according to this invention has a porous structure such that nano-size pores are three-dimensionally connected with each other wherein walls of the pores thereof are composed of olivine type LiMnPO4 and carbon, a specific surface area Sa is 55 m2g?1<Sa<248 m2g?1, an amount of contained carbon Cc is 15.5 wt %<Cc<28 w t% and a diameter of crystallite is less than 39 nm. This enables a high charge-discharge capacity and a fast charge or discharge behavior to be obtained.
    Type: Application
    Filed: June 24, 2010
    Publication date: April 26, 2012
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Isamu Moriguchi, Hirotoshi Yamada
  • Publication number: 20120094173
    Abstract: This invention provides a macroporous graphite electrode material that may be manufactured at a low temperature of 1500° C. or less and may be fast charged and discharged and a manufacturing method thereof. It also provides a lithium-ion secondary battery using this macroporous graphite electrode material. The macroporous graphite electrode material according to this invention is composed of graphite having macropores in which a ratio of specific surface area of micropores in relation to total specific surface area is not less than 0 and not more than 0.74 and a ratio of D band area and G band area in Raman spectrum (D/G area ratio) is not less than 0 and not more than 1.33.
    Type: Application
    Filed: June 24, 2010
    Publication date: April 19, 2012
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Isamu Moruiguchi, Hirotoshi Yamada
  • Publication number: 20120062299
    Abstract: Disclosed are a device and a method for comparing a detected frequency signal (first frequency signal) and a second frequency signal which is obtained by delaying the detected frequency, to determine whether the frequency transitioned to a predetermined area on high frequency side or reached a predetermined value on the upward direction side. The frequency detection device (1) comprises: a delayed signal output circuit (11) that outputs a second frequency signal (F2) obtained by delaying the first frequency signal (F1), which has a frequency that changes over time, by a set period (?i); and a determination circuit (12), which inputs the first frequency signal (F1) and the second frequency signal (F2), determines whether or not the cycle of the first frequency signal (F1) is included in the cycle of the second frequency signal (F2) and/or whether or not the cycle of the second frequency signal (F2) is included in the cycle of the first frequency signal (F1), and outputs a determination signal.
    Type: Application
    Filed: November 30, 2008
    Publication date: March 15, 2012
    Applicant: Nagasaki University, National University Corporati
    Inventor: Fujio Kurokawa
  • Patent number: 8124784
    Abstract: Disclosed is a metal complex containing a composition represented by the following formula (a). [(PdII)2(MI)2(X)2(L)4(L?)2] (In the formula (a), MI represents AgI, AuI or CuI; X represents Cl, Br or I; L represents a group represented by formula (1); L? represents a group represented by formula (2); two MIs may be the same as or different from each other; four Ls may be the same as or different from each other; and two L's may be the same as or different from each other.) (In the formulae (1) and (2), R1, R2 and R3 independently represent a hydrogen atom, a halogen atom, a hydroxy group, an optionally substituted alkyl group, an optionally substituted aryl group or an optionally substituted monovalent heterocyclic group.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: February 28, 2012
    Assignees: Nagasaki University, Sumitomo Chemical Company, Limited
    Inventors: Keisuke Umakoshi, Kazutoyo Kimura, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura, Satoshi Mikami
  • Patent number: 8089257
    Abstract: The voltage deviation is converted into the time quantity with the first integration circuit for the voltage detection and the second integration circuit for the voltage detection. The current setting value and the current measurements are converted into the time quantity with the second integration circuit for the current control to which the first integration circuit for the current control from which the voltage value of the set current value corresponding is input and the voltage value of the value of the current of the inductor corresponding are input and it controls. And, the start of the first integration circuit for the current control is delayed with operation quantity signal generation circuit only at the time that the high-resolution evaluation or more than the start of the first integration circuit for the current control and corresponds to the voltage deviation.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: January 3, 2012
    Assignee: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Patent number: 8085023
    Abstract: The control accuracy equal with the case controlled according to a reference signal with a high clock frequency when the electric power is converted is obtained according to a reference signal with a low clock frequency. The quantity of signal S3 of the time that corresponds to the difference of EO in the output voltage to reference voltage EREF by circuit 12 of the generation of quantity of signal of time is generated synchronizing with reference timing signal S1. The phase generates the class of the phase-shift signal of n piece for which only [Cycle of S0/]/n is late one by one by phase-shift signal generation circuit 13, counter circuit 14, and digital addition circuit 15, these numbers are counted respectively, and the count value of n piece is added. The control signal S5that corresponds to TON between when adding value ADD is input with decision circuit 16 of on time of the switch element and control signal generation circuit 17 and it turns it on is generated.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: December 27, 2011
    Assignee: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Publication number: 20110266506
    Abstract: Silicone surface-treated magnesium hydroxide which is surface treated by a silicone oil, the silicone oil comprising: a polyorganosiloxane containing a plurality of first siloxane units each of which contains hydrogen atom bonded silicon atom. The first siloxane units shares 50 mol % or less of total siloxane units in one molecule in average. Accordingly, sufficient fire retardancy and mechanical properties such as sufficient elongation are achieved.
    Type: Application
    Filed: July 2, 2009
    Publication date: November 3, 2011
    Applicants: YAZAKI CORPORATION, Nagasaki University, National University Corporation, DOW CORNING TORAY CO., LTD.
    Inventors: Koji Kodama, Kiyoshi Yagi, Makoto Egashira, Haruhiko Furukawa
  • Patent number: 7999716
    Abstract: There are provided an analog-digital converter circuit capable of performing the same degree of operation as being performed at a high-frequency oscillation pulse using a low-frequency oscillation pulse without using the high-frequency oscillation pulse, a timing signal generating circuit generating a timing signal at the high frequency, and a control device using the circuits. In an analog-digital converter circuit, a periodic signal generating circuit allows the first to j-th pulse counting devices of the N pulse counting devices to count a count value X and allows the other pulse counting devices to count a count value X?1 in each sampling period by sequentially generating N serial periodic signals at a delay time interval of [approximate value of one period (T) of periodic signals]÷N. A digital signal generating circuit converts the analog signal to the digital signal.
    Type: Grant
    Filed: August 22, 2007
    Date of Patent: August 16, 2011
    Assignee: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Publication number: 20110182917
    Abstract: Provided is a therapeutic or prophylactic agent for generalized pain syndrome, for which no cause and therapies have been established. A therapeutic or prophylactic agent for generalized pain syndrome containing an LPA1 antagonist or autotaxin-inhibiting substance as an active ingredient. The pharmaceutical is preferably administered to the central nervous system. The generalized pain syndrome is preferably fibromyalgia, chronic fatigue syndrome or hypersensitivity colitis.
    Type: Application
    Filed: August 7, 2009
    Publication date: July 28, 2011
    Applicants: NAGASAKI UNIVERSITY, KABUSHIKI KAISHA M.S.S
    Inventor: Hiroshi Ueda
  • Patent number: 7973167
    Abstract: A novel luminescent metal complex comprises a composition of [(PtII)2(AuI)2(MI)2(L)8] where MI denotes AgI or CuI, and L denotes a structure represented by the formula (1)
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: July 5, 2011
    Assignee: Nagasaki University
    Inventors: Keisuke Umakoshi, Keizo Saito, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura
  • Patent number: 7901724
    Abstract: A fermented tea produced by primary-drying tea material leaves by means of a primary tea rolling dryer (primary drying step) to adjust the moisture content of raw leaves (tea material leaves) of bancha with low qualities (the second crop of tea, the third crop of tea, the shuto-bancha, the skiffed leaves of tea, and the like) to a constant moisture; subsequently, providing them in a tea roller (tea rolling step); adding loquat leaves during the tea rolling step in order to knead loquat leaves together with the tea material leaves; and fermenting and drying the kneaded tea material leaves and loquat leaves. The fermented tea is formed into a composition having, as an active component, the fermented tea obtained by tea-rolling processing of tea material leaves and loquat leaves, and an extract contained in the fermented tea.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: March 8, 2011
    Assignees: Nagasaki Prefectural Government, Nagasaki Prefectural and Municipal Universities Corporation, Nagasaki University, National University Corporation, Kyushu University, National University Corporation
    Inventors: Yuuji Miyata, Kiyonori Terai, Kei Tamaya, Masamichi Maeda, Seigou Hayashida, Tomonori Tokushima, Takashi Tanaka, Kazunari Tanaka, Shouko Nishizono, Toshiro Matsui
  • Publication number: 20110046509
    Abstract: The invention provides a method for evaluating a corneal disorder quantitatively and is applicable to living eyes. In particular, the invention provides a method for measuring a corneal transepithelial electric resistance, which method comprises: (1) a step of placing a first electrode on the cornea and a second electrode on the conjunctiva; and (2) a step of flowing an electric current between the first electrode and the second electrode to measure the electric resistance. The invention also provides a device for measuring a corneal transepithelial electric resistance value.
    Type: Application
    Filed: March 3, 2009
    Publication date: February 24, 2011
    Applicants: NAGASAKI UNIVERSITY, TOHOKU UNIVERSITY
    Inventors: Masafumi Uematsu, Takashi Kitaoka, Koji Nishida, Yuji Tanaka, Matsuhiko Nishizawa, Hirokazu Kaji, Soichiro Sekine
  • Patent number: 7893611
    Abstract: There is provided a novel luminescent metal complex. A metal complex having a composition of [(PtII)2(MI)2(X)2(L)4(LH)2], where MI denotes AgI, AuI or CuI, X denotes Cl, Br or I, L denotes a structure represented by the formula (1), and LH denotes a structure represented by the formula (2).
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: February 22, 2011
    Assignee: Nagasaki University
    Inventors: Keisuke Umakoshi, Seiji Akatsu, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura
  • Publication number: 20100311982
    Abstract: Disclosed is a metal complex containing a composition represented by the following formula (a). [(PdII)2(MI)2(X)2(L)4(L?)2] (In the formula (a), MI represents AgI, AuI or CuI; X represents Cl, Br or I; L represents a group represented by formula (1); L? represents a group represented by formula (2); two MIs may be the same as or different from each other; four Ls may be the same as or different from each other; and two L's may be the same as or different from each other.) (In the formulae (1) and (2), R1, R2 and R3 independently represent a hydrogen atom, a halogen atom, a hydroxy group, an optionally substituted alkyl group, an optionally substituted aryl group or an optionally substituted monovalent heterocyclic group.
    Type: Application
    Filed: February 12, 2009
    Publication date: December 9, 2010
    Applicants: NAGASAKI UNIVERSITY, SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Keisuke Umakoshi, Kazutoyo Kimura, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura, Satoshi Mikami
  • Publication number: 20100277956
    Abstract: To detect a peak time of an exciting current of a transformer, a primary current corresponding to the peak time, or a variation time of the primary voltage, and to switch a switch after expiration of a predetermined period from the peak time, after the peak time occurs. A control apparatus 1 is applied to a power conversion circuit 2 which includes a switch circuit 23 including one switch or a plurality of switches and a transformer 21. The control apparatus includes: an output voltage detector 11 detecting a value of an output voltage of the power conversion circuit; an exciting current peak time generator 12 detecting a peak time of an exciting current of the transformer; a timing generator 13 generating a switching timing of the one switch or the plurality of switches. The timing generator 13 generates the switching timing of the one switch or the plurality of switches on the basis of the output voltage and the peak time.
    Type: Application
    Filed: October 31, 2008
    Publication date: November 4, 2010
    Applicant: NAGASAKI UNIVERSITY
    Inventor: Fujio Kurokawa
  • Publication number: 20100271096
    Abstract: A rising edge or a falling edge is finely adjusted, or a dead time and a period are adjusted with high accuracy. A waveform processing circuit includes: an integration circuit 11 receiving a rectangular or substantially-rectangular pulse and outputting a gradually increasing or decreasing signal obtained by integrating the pulse signal; a reference signal output circuit 12 outputting a constant value or a varying value as a reference signal; and a comparison circuit 13 comparing the output of the integration circuit with the output of the reference signal output circuit and outputting a pulse rising or falling at a timing when the difference between the outputs varies.
    Type: Application
    Filed: June 1, 2008
    Publication date: October 28, 2010
    Applicant: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Publication number: 20100264839
    Abstract: Provided is a discharge lamp lighting device, which can control a load precisely while improving the practicability. When the difference of a count number (Nn) becomes a predetermined threshold value or less, a predictor circuit (35) predicts the timing, at which a current value (iQ1) becomes a peak value, on the basis of the rate of change of the difference. A switch selecting circuit (38), which is driven with a clock frequency higher than the sampling frequency of a first converter unit (32), turns off a field effect transistor (Q1) at the turn-off timing, and turns on a field effect transistor (Q2). A plurality of A/D converters (37a) are subjected to a multi-rate control, thereby to correct the threshold value of the predictor circuit (35) on the basis of the peak value of a lamp current (iOUT).
    Type: Application
    Filed: October 17, 2008
    Publication date: October 21, 2010
    Applicant: NAGASAKI UNIVERSITY
    Inventor: Fujio Kurokawa
  • Publication number: 20100209923
    Abstract: The purpose of this invention is to provide a probe for diagnosis of Marfan syndrome, which enables early diagnosis of Marfan syndrome, and to provide a method for screening using said probe. The invention is a probe for a Marfan Syndrome characterized by using a nucleic acid comprising following (a) or (b); (a) a nucleic acid comprising a base sequence represented by base numbers 1-180000 shown in SEQ ID No. 1 of the sequence listing, or (b) a nucleic acid in which a part of the base sequence of said base numbers 1-180000 is deleted, substituted or added, and having 80% homology with said base sequence.
    Type: Application
    Filed: February 2, 2010
    Publication date: August 19, 2010
    Applicants: NAGASAKI UNIVERSITY, INSTITUT NATIONAL DE LE SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Norio Niikawa, Naomichi Matsumoto, Catherine Boileau, Gwenaielle Beroud, Guillaume Jondeau