Abstract: A tert-alkyl ketone, pinacolone was hydrogenated under pressurized hydrogen in the presence of a ruthenium complex (S)-1 and a base, and corresponding (S)-3,3,-dimethyl-2-butanol was thereby obtained in 100% yield and 97% ee.
Type:
Application
Filed:
October 24, 2005
Publication date:
November 15, 2007
Applicants:
Kanto Kagaku Kabushiki Kaisha, Nagoya Industrial Science Research Insitute
Inventors:
Takeshi Ohkuma, Christian Sandoval, Ryoji Noyori