Patents Assigned to Nanjing Cavendish Bio-Engineering Tech. Co., LTD.
  • Method for synthesis of Roxadustat and intermediate compounds thereof
    Patent number: 11465970
    Abstract: The present application provides a method for synthesis of Roxadustat. A compound as represented by formula (VIII) is used as a raw material, and is reacted with phenol, a vinyl-containing ether, an acid, hydroxylamine, and then the product is reacted with glycine. In addition, the present application also provides intermediate compounds as represented by formula (IX), formula (XI), formula (XII), formula (IV), and formula (V) for synthesis of Roxadustat.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: October 11, 2022
    Assignees: Nanjing Cavendish Bio-Engineering Tech. Co., LTD.
    Inventor: Yongxiang Xu