Patents Assigned to Nanjing University of Technology
  • Patent number: 9434621
    Abstract: A mesoporous composite titanium oxide, which is composed of a mesoporous titanium oxide, the outside surface and the wall of pores of the mesoporous titanium oxide are modified by inorganic matters; inorganic matter contains at least one element selected from carbon, silicon, sulphur, phosphorus and selenium in an amount of 0.01%-25%, on amount of the element mass, of the mass of said mesoporous composite titanium oxide material; at least one mean pore size of pore distribution of the mesoporous compound titanium oxide material is 3-15 nm, the specific surface area is 50-250 m2/g, and the pore volume is 0.05-0.4 cm3/g. As a catalyst carrier, the rate of conversion of the hydrodesulfurization reaction of the material reaches as high as 98 percent, and as a lithium ion battery cathode material, the specific capacity of the lithium ion battery cathode material reaches as high as 220 mAh/g.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: September 6, 2016
    Assignees: NANJING UNIVERSITY OF TECHNOLOGY, NANJING TAIWEI TECHNOLOGY CO., LTD.
    Inventors: Zhuhong Yang, Yudan Zhu, Xiaohua Lu, Changsong Wang, Licheng Li, Linghong Lv, Wei Zhuang, Chang Liu, Xin Feng
  • Publication number: 20160250623
    Abstract: The invention relates to a catalyst for benzene hydroxylation for preparation of phenol and a preparation method thereof, wherein said catalyst uses a mesoporous material as carrier, and the catalyst is prepared by first modifying the surface of the carrier using aminosilane, then immersing with acetylacetonate salt of metal, and finally washing and drying. Advantage of the invention is that a reactive metal is loaded on the silane-modified mesoporous material to form a homogeneous-heterogeneous composite catalyst, wherein, the reactive metal component is present in a reaction system in a homogeneous form, which ensures high catalytic performance of the catalyst component, and it is loaded on the carrier through bridging action of aminosilane, which improves the acting force between the metal component and the carrier, enhances stability of the catalyst, and facilitates separation of the catalyst from the product.
    Type: Application
    Filed: September 12, 2014
    Publication date: September 1, 2016
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Rizhi CHEN, Yaohui BAO, Hong JIANG, Yiqun FAN, Weihong XING
  • Patent number: 9416385
    Abstract: The invention relates to a method for the production of adenosine 3?,5?-monophosphate (cAMP) by a permeable microbial strain which uses polyols for protecting activities of enzymes and a cAMP precursor and phosphate as substrates. Glucose is used as an energy provider and metal ions and an organic solvent such as acetone are used in the medium.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: August 16, 2016
    Assignee: Nanjing University of Technology
    Inventors: Hanjie Ying, Jianxin Bai, He Song, Xiaochun Chen, Jian Xiong, Yong Chen, Jingjing Xie, Jinglan Wu
  • Publication number: 20160214064
    Abstract: The invention relates to a high-strength hollow fiber zeolite membrane and its preparation method, characterized in that the support of the high-strength zeolite membrane has a multi-channel hollow fiber configuration. The preparation method comprises first preparing a crystal seed solution, then immersing the dry support with the multi-channel hollow fiber configuration in the crystal seed solution, and extracting and drying the support to obtain a crystal-seeded support; and finally placing the crystal-seeded support in a zeolite membrane synthetic fluid, performing hydrothermal synthesis, and taking out, washing and drying the product to obtain the high-strength hollow fiber zeolite membrane. The multi-channel hollow fiber support can provide high mechanical property, which greatly reduces the depreciation rate of the hollow fiber zeolite membrane equipment during use.
    Type: Application
    Filed: May 9, 2014
    Publication date: July 28, 2016
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Xuehong GU, Dezhong LIU, Zhenzhou SHI, Chun ZHANG, Xuerui WANG
  • Patent number: 9382429
    Abstract: A preparation method of carbon modified filler is provided. The method is: putting the fillers into the reaction zone of a reactor, starting the first heating-up to 400-500° C. under the protective atmosphere at first, then introducing hydrogen after the heating-up; starting the second heating-up to 600-1200° C. after introducing hydrogen and simultaneously introducing the mixture of hydrogen and carbon source gas, keeping at the terminal temperature for 0.1-5 hours, introducing nitrogen and stopping heating after the reaction, cooling, and then getting the carbon modified filler. The above method can obtain a friction material with good mechanical properties, excellent friction and wear performances, stable friction coefficient at high temperature, good braking force and no heat recession.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: July 5, 2016
    Assignees: NANJING TAIWEI TECHNOLOGY CO., LTD., NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaohua Lu, Yijun Shi, Ke Zhou, Changsong Wang, Wenjun Yao
  • Publication number: 20160145303
    Abstract: The present invention belongs to protein engineering and genetic engineering fields, relating to a strong secretory signal peptide enhancing small peptide motifs and the use thereof. The strong secretory signal peptide enhancing small peptide motifs of the present invention have the amino acid sequence of the following formula: M (?X?Y?/?Y?X?)n, wherein X represents an acidic amino acid; Y represents an alkaline amino acid; ? is 0 to 2 neutral amino acid(s); ? represents 0 to 2 neutral amino acid(s); ? represents 1 to 10 neutral amino acid(s); n is 1 to 3. With regard to the use of the strong secretory signal peptide enhancing small peptide motifs of the present invention, it is a method for constructing a vector enhancing the secretion ability of common signal peptides to improve the secretory expression of exogenous proteins.
    Type: Application
    Filed: April 25, 2014
    Publication date: May 26, 2016
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Bingfang HE, Wenhua CHEN, Lan MI, Shanshan WU, Yun ZHU, Shanshan CHEN
  • Publication number: 20160137557
    Abstract: The Invention relates to a method for preparing a multichannel hollow fiber membrane. According to a certain ratio, ceramic powder, a macromolecular polymer, an organic solvent, and a dispersant are mixed evenly to prepare a membrane casting solution; and after bubble removing processing is performed on the membrane casting solution, a membrane green body is formed with the cooperation of a multichannel hollow fiber die and phase inversion. After the membrane green body is roasted at a high temperature, a multichannel ceramic hollow fiber membrane is formed. The multichannel ceramic hollow fiber membrane has an asymmetric structure and a skeleton structure in an inner cavity and can meet the strength and flux requirements of a ceramic hollow fiber membrane.
    Type: Application
    Filed: May 9, 2014
    Publication date: May 19, 2016
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Xuehong GU, Zhenzhou SHI, Yuanyuan CHEN, Chun ZHANG, Nanping XU
  • Patent number: 9249433
    Abstract: The present invention provides Clostridium acetobutylicum and an application thereof. A preservation number of the Clostridium acetobutylicum provided in the invention is CGMCC No. 5234. The Clostridium acetobutylicum provided in the present invention can be used for cogeneration of acetone, butanol, ethanol, and 3-hydroxy butanone through fermentation, so as to improve the economic benefit of butanol fermentation. NAD+ coupling and regeneration can be implemented by adding metabolism or growth regulating substances, so as to improve the product yield, and at the same time, the yield of cogeneration products can be flexibly adjusted, so as to cater for the market demand.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: February 2, 2016
    Assignee: Nanjing University of Technology
    Inventors: Hanjie Ying, Dong Liu, Yong Chen, An Li, Tao Zhou, Jinglan Wu, Xiaoqing Lin, Xiaochun Chen, Jingjing Xie, Jianxin Bai
  • Publication number: 20160017308
    Abstract: It discloses a use of N-acetylneuraminic acid aldolase with an amino acid sequence as shown in SEQ ID NO: 2 in catalytic synthesis of N-acetylneuraminic acid. The preparation of N-acetylneuraminic acid is to use the N-acetylneuraminic acid aldolase with the amino acid sequence as shown in SEQ ID NO: 2 as a catalyst, and N-acetylmannosamine and pyruvic acid as substrates.
    Type: Application
    Filed: November 27, 2013
    Publication date: January 21, 2016
    Applicant: Nanjing University of Technology
    Inventors: Jingjing Xie, Wenyan Ji, Hanjie Ying, Wujin Sun, Ting Guo, Yong Chen, Xiaochun Chen, Jinglan Wu
  • Patent number: 9187394
    Abstract: Provided in the present invention is a method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: November 17, 2015
    Assignees: Nanjing University of Technology, Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
    Inventors: Chunlei Lv, Shiqing Pi, Jianhui Chen, Dingqiang Lu, Pingkai Ouyang
  • Patent number: 9108897
    Abstract: The present invention provides a method for desorbing and regenerating a butanol-adsorbing hydrophobic macroporous polymer adsorbent, comprising: successively eluting the hydrophobic macroporous polymer adsorbent with butanol adsorbed therein using a water soluble low-boiling-point polar solvent and water. The method provided in the present invention has a simple process, a short separation time, easy, fast and complete desorption and regeneration, low equipment investment and pollution, and reduced energy consumption, and therefore production is easy on a large scale.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: August 18, 2015
    Assignee: Nanjing University of Technology
    Inventors: Hanjie Ying, Xiaoqing Lin, Jiansheng Fan, Jinglan Wu, Yong Chen, Xiaochun Chen, Jingjing Xie, Jian Xiong, Jianxin Bai
  • Patent number: 9040653
    Abstract: This disclosure provides methods of controlled polymerization of cyclic compounds catalyzed by carbene derivatives having a general formula as shown below, and to obtain a biodegradable polymeric material having a large molecular weight, a narrow dispersity, and no metallic impurity.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: May 26, 2015
    Assignee: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Zhenjiang Li, Pingkai Ouyang, He Huang
  • Patent number: 9029497
    Abstract: This disclosure provides a method of making polylactic acid using carbon dioxide adducts of carbenes, wherein the adducts of carbenes have a structure represented by formula (I) as follows:
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: May 12, 2015
    Assignee: Nanjing University of Technology
    Inventors: Zhenjiang Li, Pingkai Ouyang, He Huang
  • Patent number: 8993810
    Abstract: Disclosed is a preparation method of the lycopene intermediate 3-methyl-4,4-dialkoxy-1-butaldehyde. The preparation method comprises the following steps: (1) reacting 2-methyl-3,3-dialkoxy-1-halopropane with magnesium powder in the solvent of anhydrous tetrahydrofuran at a temperature of 45˜65° C. to generate a mixture of Grignard reagents under the protection of an inert gas; and (2) adding N,N-disubstituted carboxamide to the mixture of Grignard reagents and reacting at a temperature of 10° C.˜35° C. to obtain 3-methyl-4,4-dialkoxy-1-butaldehyde. The process route of the present invention is simple and direct, the operation is easy, the conditions are mild and the yield is good, and thus the invention has commercial value.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: March 31, 2015
    Assignees: Nanjing University of Technology, Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
    Inventors: Chunlei LV, Shiqing Pi, Jianhui Chen, Dingqiang Lu, Pingkai Ouyang
  • Publication number: 20150050579
    Abstract: The present invention relates to a medium and high-temperature carbon-air cell, which include a solid oxide fuel cell, a CO2 separation membrane and a carbon fuel. The solid oxide fuel cell is a tubular solid oxide fuel cell with one end closed, the carbon fuel is placed inside the tubular solid oxide fuel cell, and the CO2 separation membrane is sealed at the open end of the solid oxide fuel cell. In the carbon-air cell, with carbon as fuel and oxygen in the air as an oxidizing gas, electrochemical reactions occur. The carbon-air cell of the present invention has a novel structural design, and can achieve electricity generation with the solid oxide fuel cell without externally charging a gas, and at the same time, CO2 generated inside the solid oxide fuel cell can be discharged from the system through the CO2 separation membrane in time.
    Type: Application
    Filed: March 26, 2013
    Publication date: February 19, 2015
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Ran Ran, Huangang Shi, Binbin Yang, Guangming Yang, Chao Li, Zongping Shao
  • Patent number: 8946407
    Abstract: Provided are a fructosylated mangiferin, a preparation method therefor and a use thereof, wherein the fructosylated mangiferin has a structural formula represented by the following formula (I), the method for preparing the fructosylated mangiferin includes adding a substance with fructosylating enzymatic activity to a transformed liquid containing mangiferin for biotransformation reaction, so as to convert the mangiferin into the fructosylated mangiferin, wherein the transformed liquid contains the mangiferin and a glycosyl donor; as well as a use of the fructosylated mangiferin in preparation of a medicament for treatment of tumor-related diseases.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: February 3, 2015
    Assignee: Nanjing University of Technology
    Inventors: Bingfang He, Xueming Wu, Jianlin Chu, Bin Wu, Sen Zhang, Pingkai Ouyang
  • Publication number: 20140349356
    Abstract: This invention belongs to the field of biochemical engineering and relates to a method of cyclic utilization of water during separation of succinic acid made by fermentation. This invention uses water from separation process for aerobic growth of E.coli AFP111 and production of succinic acid by anaerobic fermentation, obtaining final succinic acid concentration of 55 g/L and yield of 91.6%. Compared with results of fermentation using culture medium prepared from tap water, succinic acid concentration and productivity increased by 8.5% and 8.46%, respectively. An outstanding advantage of this invention is recovery and utilization of evaporated water during separation of succinic acid, realizing cyclic use of water during industrial production of succinic acid, which is an environment-friendly process.
    Type: Application
    Filed: September 13, 2012
    Publication date: November 27, 2014
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Min Jiang, Min Zhang, Jiangfeng Ma, Hao Wu, Liya Liang, Rongming Liu, Guangming Wang, Ping Wei
  • Patent number: 8809420
    Abstract: A method for preparing organic-inorganic composite materials is provided. It is a dispersion method that the inorganic phase is introduced into the polymer matrix uniformly. The core-shell structure, in which the inorganic materials are core and the organic materials are shell, is formed by first wrapping the inorganic materials with the organic materials in the same reactor. Therefore, the match between the polarity of inorganic phase and the polarity of polymer phase is increased.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: August 19, 2014
    Assignee: Nanjing University of Technology
    Inventors: Wang Wei, Gongping Liu, Nanping Xu, Wanqin Jin
  • Publication number: 20140221643
    Abstract: Provided are a fructosylated mangiferin, a preparation method therefor and a use thereof, wherein the fructosylated mangiferin has a structural formula represented by the following formula (I), the method for preparing the fructosylated mangiferin includes adding a substance with fructosylating enzymatic activity to a transformed liquid containing mangiferin for biotransformation reaction, so as to convert the mangiferin into the fructosylated mangiferin, wherein the transformed liquid contains the mangiferin and a glycosyl donor; as well as a use of the fructosylated mangiferin in preparation of a medicament for treatment of tumor-related diseases.
    Type: Application
    Filed: March 8, 2012
    Publication date: August 7, 2014
    Applicant: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Bingfang He, Xueming Wu, Jianlin Chu, Bin Wu, Sen Zhang, Pingkai Ouyang
  • Patent number: 8766019
    Abstract: Disclosed is a method for separating butanol. The method uses hydrophobic macroporous polymer adsorbent to separate butanol in a mixed solution, and the process comprises the following steps: 1) using macroporous polymer adsorbent to adsorb butanol in a mixed solution; 2) desorbing butanol from macroporous polymer adsorbent. The method is simple; the separation time is short; the efficiency of butanol recovery is high; and the separating cost is low.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 1, 2014
    Assignee: Nanjing University of Technology
    Inventors: Hanjie Ying, Xiaoqing Lin, Yong Chen, Xiaochun Chen, Jianxin Bai, Jian Xiong, Wenbin Qian, Jingjing Xie, Jinglan Wu