Patents Assigned to Nanning Maple Leaf Pharmaceutical Co., Ltd.
  • Method of purifying tetrodotoxin
    Patent number: 6562968
    Abstract: The present invention relates to a new process of purifying tetrodotoxin using high performance liquid chromatograph technology.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: May 13, 2003
    Assignee: Nanning Maple Leaf Pharmaceutical Co., Ltd.
    Inventors: Maoqing Zhou, Frank Hay Kong Shum
  • Composition of sodium channel blocking compound
    Patent number: 6559154
    Abstract: The composition of the present invention comprises a sodium channel blocking compound which is capable of specifically binding to a site, either on an SS1 region or an SS2 region, on an extracellular region of a sodium channel alpha subunit, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: May 6, 2003
    Assignee: Nanning Maple Leaf Pharmaceutical Co., Ltd.
    Inventors: Yuhong Kang, Frank Hay Kong Shum
  • System for extracting tetrodotoxin
    Patent number: 6478966
    Abstract: The invention relates to a system for extracting toxins from biological tissues. The system comprises a lixiviator, an ion-exchange column, a diatomaceous silica-active carbon column, and a vacuum concentrator. Twenty to one hundred kilograms of raw material can be processed at one time when puffer fish ovaries are used as the starting material.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: November 12, 2002
    Assignee: Nanning Maple Leaf Pharmaceutical Co., Ltd.
    Inventors: Maoqing Zhou, Frank Hay Kong Shum
  • Use of amino hydrogenated quinazoline compounds and derivatives thereof for abstaining from drug dependence
    Patent number: 5846975
    Abstract: This invention relates to the use of amino hydrogenated quinazoline compounds and derivatives thereof, such as tetrodotoxin, for abstaining from drug dependence in human. Such compounds are administered by subcutaneous, intramuscular or intravenous injection for abstaining from drug dependence, the said drug is alkaloids and nitrogen-containing non-amino acid compound, for example opium, morphine, heroin and the like. Such compounds without drug dependence and low toxicity and side effect can abstain rapidly from drug dependence.
    Type: Grant
    Filed: May 21, 1996
    Date of Patent: December 8, 1998
    Assignee: Nanning Maple Leaf Pharmaceutical Co., Ltd.
    Inventors: Xinfu Pan, Fanglong Qiu