Abstract: The present invention relates to a process of treating an implant, comprising a step of treating the surface of the implant with at least one phosphonic acid compound or a pharmaceutically acceptable salt, ester or amide thereof under sonication at a temperature of about 50° C. to about 90° C. This process is highly advantageous in that it allows the formation of a monolayer of the phosphonic acid compound on the implant surface, having a particularly dense surface coverage which, in turn, results in an improved implant biocompatibility and improved osseointegration.
Type:
Grant
Filed:
February 13, 2017
Date of Patent:
May 11, 2021
Assignee:
NANO BRIDGING MOLECULES SA
Inventors:
Sabrina Buchini, Richard Curno, Björn-Owe Aronsson, Péter Péchy
Abstract: The present invention relates to a process of treating an implant, comprising a step of treating the surface of the implant with at least one phosphonic acid compound or a pharmaceutically acceptable salt, ester or amide thereof under sonication at a temperature of about 50° C. to about 90° C. This process is highly advantageous in that it allows the formation of a monolayer of the phosphonic acid compound on the implant surface, having a particularly dense surface coverage which, in turn, results in an improved implant biocompatibility and improved osseointegration.
Type:
Application
Filed:
February 13, 2017
Publication date:
February 7, 2019
Applicant:
Nano Bridging Molecules SA
Inventors:
Sabrina BUCHINI, Richard CURNO, Björn-Owe ARONSSON, Péter PÉCHY