Patents Assigned to Nanodelivery, Inc.
  • Patent number: 6589563
    Abstract: Microparticles and nanoparticles prepared from oppositely charged polymers are provided in which a drug is incorporated into the core and is conjugated to one polymer by a Schiff-base crosslink. The particles are suitable for use in injectable formulations in which the rate of release of the drug through the particle shell is slowed as compared to noncrosslinked drugs. Enzymatically degradable polymers can be incorporated in otherwise hydrolytically stable particles to provide drug release at particular sites within the body where the enzyme of interest is present.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: July 8, 2003
    Assignee: Nanodelivery, Inc.
    Inventor: Ales Prokop
  • Publication number: 20030035838
    Abstract: Microparticles and nanoparticles prepared from oppositely charged polymers are provided in which a drug is incorporated into the core and is conjugated to one polymer by a Schiff-base crosslink. The particles are suitable for use in injectable formulations in which the rate of release of the drug through the particle shell is slowed as compared to noncrosslinked drugs. Enzymatically degradable polymers can be incorporated in otherwise hydrolytically stable particles to provide drug release at particular sites within the body where the enzyme of interest is present.
    Type: Application
    Filed: September 27, 2002
    Publication date: February 20, 2003
    Applicant: NanoDelivery, Inc.
    Inventor: Ales Prokop
  • Patent number: 6482439
    Abstract: Microparticles and nanoparticles prepared from oppositely charged polymers are provided in which a drug is incorporated into the core and is conjugated to one polymer by a Schiff-base crosslink. The particles are suitable for use in injectable formulations in which the rate of release of the drug through the particle shell is slowed as compared to noncrosslinked drugs. Enzymatically degradable polymers can be incorporated in otherwise hydrolytically stable particles to provide drug release at particular sites within the body where the enzyme of interest is present.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: November 19, 2002
    Assignee: Nanodelivery, Inc.
    Inventor: Ales Prokop