Patents Assigned to NANODERM SCIENCES, INC.
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Patent number: 10799600Abstract: The invention in the various aspects provides nanogel compositions that are safe for topical, local, and/or systemic delivery, and which can be targeted to select tissues or cells, including pathogens. In some embodiments, conjugation of antibiotics to the nanogel surface, and in particular antibiotics that disrupt outer membranes of Gram negative bacteria or antibiotics that inhibit cell wall synthesis, provide for highly effective targeting and killing of bacterial pathogens, including drug-resistant bacteria.Type: GrantFiled: April 15, 2019Date of Patent: October 13, 2020Assignee: NANODERM SCIENCES, INC.Inventors: Roy R. Yeoman, Richard A. Winchurch
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Publication number: 20180028684Abstract: The invention in the various aspects provides nanogel compositions that are safe for topical, local, and/or systemic delivery, and which can be targeted to select tissues or cells, including pathogens. In some embodiments, conjugation of antibiotics to the nanogel surface, and in particular antibiotics that disrupt outer membranes of Gram negative bacteria or antibiotics that inhibit cell wall synthesis, provide for highly effective targeting and killing of bacterial pathogens, including drug-resistant bacteria.Type: ApplicationFiled: June 20, 2017Publication date: February 1, 2018Applicant: nanoDERM Sciences, Inc.Inventors: Roy R. Yeoman, Richard A. Winchurch
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Patent number: 9694085Abstract: Disclosure of methods and compositions related to chemical conjugations to nanoparticles of polysaccharides cross-linked to poloxamers as well as nano-sized colloids comprised of polysaccharides and poloxamers. The nanoparticles may be produced by various methods including inverse miniemulsion polymerization processes which create nanogels of desired size, shape, and stability for controlled therapeutic drug delivery, imaging, and theragnostic applications.Type: GrantFiled: September 8, 2015Date of Patent: July 4, 2017Assignee: nanoDERM Sciences, Inc.Inventors: Roy R. Yeoman, Richard A. Winchurch
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Publication number: 20160106852Abstract: Disclosure of methods and compositions related to chemical conjugations to nanoparticles of polysaccharides cross-linked to poloxamers as well as nano-sized colloids comprised of polysaccharides and poloxamers. The nanoparticles may be produced by various methods including inverse miniemulsion polymerization processes which create nanogels of desired size, shape, and stability for controlled therapeutic drug delivery, imaging, and theragnostic applications.Type: ApplicationFiled: September 8, 2015Publication date: April 21, 2016Applicant: nanoDERM SCIENCES, INC.Inventors: Roy R. Yeoman, Richard A. Winchurch
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Patent number: 9161962Abstract: Disclosure of methods and compositions related to chemical conjugations to nanoparticles of polysaccharides cross-linked to poloxamers as well as nano-sized colloids comprised of polysaccharides and poloxamers. The nanoparticles may be produced by various methods including inverse miniemulsion polymerization processes which create nanogels of desired size, shape, and stability for controlled therapeutic drug delivery, imaging, and theragnostic applications.Type: GrantFiled: July 16, 2013Date of Patent: October 20, 2015Assignee: nanoDERM Sciences, Inc.Inventors: Roy R. Yeoman, Richard A. Winchurch
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Patent number: 8821933Abstract: Methods and compositions related polymers and hydrogels. In some cases to biodegradable hydrogels for use in medical applications are disclosed. The polymers and hydrogels may be produced from cross-linked dextran and poly(epoxides). The poly(epoxides) may be poloxamers.Type: GrantFiled: November 1, 2011Date of Patent: September 2, 2014Assignee: nanoDERM Sciences, Inc.Inventors: Roy R. Yeoman, Adrian S. Fox
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Publication number: 20140199232Abstract: Disclosure of methods and compositions related to chemical conjugations to nanoparticles of polysaccharides cross-linked to poloxamers as well as nano-sized colloids comprised of polysaccharides and poloxamers. The nanoparticles may be produced by various methods including inverse miniemulsion polymerization processes which create nanogels of desired size, shape, and stability for controlled therapeutic drug delivery, imaging, and theragnostic applications.Type: ApplicationFiled: July 16, 2013Publication date: July 17, 2014Applicant: NANODERM SCIENCES, INC.Inventors: Richard A. Winchurch, Roy R. Yeoman