Abstract: The invention relates to a method and a device for producing nanoparticles of organic substances, in particular by controlled expansion of pressurized solutions. The method comprises: admixing the organic substance and a supercritical fluid to form a mixture at a first pressure; decreasing the first pressure gradually to a second pressure so that a flow of the mixture is formed and nucleation of the organic substance in the mixture is initiated; and, decreasing the second pressure to a third pressure, so that solidification of the fluid of the mixture, comprising the nucleated organic substance, is initiated. The device comprises: a pressure chamber (1) for a mixture of the organic substance and a supercritical fluid; a collection chamber (5) for the nanoparticles; an outlet tube (2) connecting the pressure chamber to the collection chamber (5); and, one or more second nozzles (6).
Type:
Grant
Filed:
October 5, 2015
Date of Patent:
October 16, 2018
Assignee:
Nanoform Finland Oy
Inventors:
Edward Haeggström, Jouko Yliruusi, Kai Falck, Heikki Räikkönen, Jenni Pessi, Ilkka Lassila, Antti Meriläinen
Abstract: The invention relates to a method and a device for producing nanoparticles of organic substances, in particular by controlled expansion of pressurized solutions. The method comprises: admixing the organic substance and a supercritical fluid to form a mixture at a first pressure; decreasing the first pressure gradually to a second pressure so that a flow of the mixture is formed and nucleation of the organic substance in the mixture is initiated; and, decreasing the second pressure to a third pressure, so that solidification of the fluid of the mixture, comprising the nucleated organic substance, is initiated. The device comprises: a pressure chamber (1) for a mixture of the organic substance and a supercritical fluid; a collection chamber (5) for the nanoparticles; an outlet tube (2) connecting the pressure chamber to the collection chamber (5); and, one or more second nozzles (6).
Type:
Application
Filed:
October 5, 2015
Publication date:
August 17, 2017
Applicant:
Nanoform Finland Oy
Inventors:
Edward HAEGGSTRÖM, Jouko Yliruusi, Kai FALCK, Heikki RÄIKKÖNEN, Jenni PESSI, Ilkka LASSILA, Antti MERILÄINEN