Abstract: A process for producing a nonapeptide leuprolide and an intermediate N-protected oligopetides, wherein at least one peptide bond of the compound is formed by reacting an activated carboxylic acid and an amine component in a continuous flow.
Type:
Grant
Filed:
November 21, 2006
Date of Patent:
September 6, 2011
Assignee:
Nanokem S.A.
Inventors:
Daniel Kadzimirsz, Gerhard Jas, Volker Autze
Abstract: The invention relates to a process for producing the nonapeptide leuprolide and the intermediate N-protected oligopetides thereof, wherein at least one peptide bond of the compound is formed by reacting an activated carboxylic acid and an amine component in a continuous flow.
Type:
Application
Filed:
November 21, 2006
Publication date:
January 1, 2009
Applicant:
NANOKEM S.A.
Inventors:
Daniel Kadzimirzs, Gerhard Jas, Volker Autze