Abstract: There is disclosed a tin-containing metal oxide nanoparticle, which has an index of dispersion degree less than 7 and a narrow particle size distribution which is defined as steepness ratio less than 3. There is disclosed dispersion, paint, shielding film and their glass products which comprise the said nanoparticles. Besides, there are also disclosed processes of making the tin-containing metal oxide nanoparticle and their dispersion. The tin-containing metal oxide nanoparticles and their dispersion disclosed herein may be applied on the window glass of houses, buildings, vehicles, ships, etc. There is provided an excellent function of infrared blocking with highly transparent, and to achieve sunlight controlling and thermal radiation controlling.

Abstract: Iron oxide nanoparticle compositions, methods of preparing the nanoparticles using high gravity controlled precipitation (HGCP), and methods of using the nanoparticles are disclosed.

Abstract: A microchannel double pipe device comprises a channel for inner nozzle (4), a channel for outer nozzle (5) and a mechanical probe (8). The channel for outer nozzle (5) concentrically surrounds the channel for inner nozzle (4), and the channel for inner nozzle (4) concentrically surrounds the mechanical probe (8). Constricted at the outlet of the channel for inner nozzle (4), the channel for inner nozzle (4) extends to form an inner nozzle core (9). Constricted at the outlet of the channel for outer nozzle (5), the channel for outer nozzle (5) extends to form an outer nozzle core (10). The outer nozzle core (10) essentially concentrically surrounds the inner nozzle core (9), and the outlets of the inner nozzle core (9) and the outer nozzle core (10) are at the same level essentially. The mechanical probe (8) is configured to intermittently empty the inner nozzle core (9).

Abstract: There is disclosed a process of making metal chalcogenide particles. The process comprises the steps of reacting a metal salt solution with a precipitant solution under conditions to form metal chalcogenide particles and by-product thereof, coating the metal chalcogenide particles with a surfactant; and separating the surfactant coated chalcogenide particles from the by-product to obtain metal chalcogenide particles substantially free of by-product.

Abstract: The present invention relates to a method for preparing nano-sized iron phosphate particles, the method including the steps of: mixing an iron salt solution and a phosphate solution in a reactor in order to prepare a suspension containing amorphous or crystalline iron phosphate precipitate; and applying a shearing force to the mixed solution inside the reactor during the step of mixing, wherein the suspension containing nano-sized iron phosphate precipitate particles is formed by means of the shearing force and the conditions inside the reactor. According to the present invention, micro-mixing takes place faster than nucleation, which provides an advantage for preparing nanoparticles and for preparing particles having a uniform particle size distribution.

Abstract: A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where the formed nanoparticles have a narrow particle size distribution; (b) providing an excipient to at least one of the precipitant solution, the anti-solvent solution and the suspension of drug nanoparticles, the excipient being selected to maintain said drug nanoparticles in a dispersed state when in liquid form; and (c) drying the suspension of drug nanoparticles containing the excipient therein to remove solvent therefrom, wherein removal of the solvent causes the excipient to solidify and thereby form micro-sized matrix particles, each micro-sized particle being comprised of drug nanoparticles dispersed in a solid matrix of the excipient.

Abstract: A process of making micro-sized protein particles comprising the step of drying nano-sized protein particles suspended in a liquid medium under conditions to agglomerate the nano-sized protein particles and thereby form micro-sized protein particles.

Abstract: There is disclosed a process of making nano-sized or micro-sized precipitate particles. The process comprising the steps of mixing, in a reaction zone, a metal salt solution with a precipitant solution to form a precipitate, said precipitate being at least one of a metal chalcogenide, metal hydroxide and metal oxide; and applying a shear force to said mixing solutions in said reaction zone during said mixing step, wherein said shear force and the conditions within said reaction zone form said nano-sized or micro-sized precipitate particles.

Abstract: A process for the production of a microparticle or a nanoparticle of a chemical compound comprising the steps of providing a solution of said chemical compound in a first liquid; providing a second liquid in which said chemical compound is insoluble or substantially insoluble; combining said liquids in a region of high shear thereby causing formation of said particles; and isolating said particles of said compound. The processing time of a coacervation style process can be reduced and the yield can be substantially increased both by control of the precipitation step which allows for desolvation step to be dispensed with leading to significant process time reduction. The invention also provides a molecular mixing unit comprising an outer body defining a mixing zone; a shear means to provide shear liquid in said mixing zone; at least one fluid inlet means for a first liquid; at least one fluid inlet means for a second liquid and a fluid outlet means.

Abstract: There is disclosed a process of making metal chalcogenide particles. The process comprises the steps of reacting a metal salt solution with a precipitant solution under conditions to form metal chalcogenide particles and by-product thereof, coating the metal chalcogenide particles with a surfactant; and separating the surfactant coated chalcogenide particles from the by-product to obtain metal chalcogenide particles substantially free of by-product.

Abstract: There is disclosed a process of making nano-sized or micro-sized precipitate particles. The process comprising the steps of mixing, in a reaction zone, a metal salt solution with a precipitant solution to form a precipitate, said precipitate being at least one of a metal chalcogenide, metal hydroxide and metal oxide; and applying a shear force to said mixing solutions in said reaction zone during said mixing step, wherein said shear force and the conditions within said reaction zone form said nano-sized or micro-sized precipitate particles.

Abstract: A process for preparation of particles of an inhalable drug is described. The process comprises combining a first liquid and a second liquid in a region of high shear, whereby the first liquid and the second liquid interact to form the particles of the drug. One of the first and second liquids comprises the drug or a precursor thereof. In the case where one of the liquids comprises the precursor, the other of the first and second liquids comprises a reagent which reacts with the precursor under high shear conditions to form particles of the drug. In the case where one of the liquids comprises the drug, the other of the first and second liquids comprises a liquid which, when mixed with the liquid containing the drug under high shear, forms particles of the drug.

Abstract: A novel process for the preparation of amorphous cefuroxime axetil particles and the amorphous cefuroxime axetil particles therefrom are disclosed in the invention. Specifically, the invention is implemented by means of antisolvent recrystallization to prepare the cefuroxime axetil in an amorphous form; particularly, the amorphous ultrafine or even nanosized cefuroxime axetil with a controllable particle size and a narrow particle size distribution. The cefuroxime axetil according to the invention can used to enhance bioavailability, since it is in an amorphous form and has a controllable particle size and a narrow particle size distribution.

Abstract: The invention provides CaCO3/SiO2.nH2O nanocomposite particles and method of producing the same. A template nucleus is used calcium carbonate and the surface of nucleus is encapsulated by a SiO2.nH2O nanolayer. The invention also provides a CaCO3/SiO2.nH2O nanocomposite particles having hollow structure, in which n=0-2. The nanocomposite particles according to the invention have a number of uses.

Abstract: The invention provides CaCO3/SiO2·nH2O nanocomposite particles and method of producing the same. A template nucleus is used calcium carbonate and the surface of nucleus is encapsulated by a SiO2·nH2O nanolayer. The invention also provides a CaCO3/SiO2·nH2O nanocomposite particles having hollow structure, in which n=0-2. The nanocomposite particles according to the invention have a number of uses.

Abstract: A process of making dispersant-coated carbon particles comprising the steps of providing a liquid mixture comprising carbon particles and a dispersant, and imparting a shear force to the liquid mixture to thereby form said dispersant-coated carbon particles.