Abstract: The present invention relates to the synthesis, composition and use of novel moieties formed by reacting a transimination nucleophilic catalyst, molecular or polymeric, with carbonyl-containing therapeutic or cosmetic moieties. The resultant Schiff base product is highly reactive towards transimination with a biological amine. The catalyst and carbonyl-containing moiety can be molecular or polymeric, and the resultant chemical and physical properties of the Schiff base products can be engineered by appropriate selection of said catalyst. The present invention also relates to the synthesis, composition and use of novel moieties that are used as actives in sunless tanning preparations. The present invention also relates to the use of transimination nucleophilic catalysts to increase the rate at which a carbonyl-containing moiety reacts with a biological amine.

Abstract: A method for manufacturing a clad component in which a cladding workpiece having a section comprising a first metal onto which a number of metal beads are rigidly bonded is inserted into a mold. A molten second metal is poured into the mold, where it flows about and covers the beads and is then permitted to cool. This process forms an article made of the second metal, which is mechanically interlocked to the beads, clad by the first metal. Typically the first metal is a high-melting point strong metal, such as steel, and the second metal is a lower-melting point, weaker, but lighter metal, such as aluminum.

Abstract: A method for manufacturing a clad component in which a cladding workpiece having a section comprising a first metal onto which a number of metal beads are rigidly bonded is inserted into a mold. A molten second metal is poured into the mold, where it flows about and covers the beads and is then permitted to cool. This process forms an article made of the second metal, which is mechanically interlocked to the beads, clad by the first metal. Typically the first metal is a high-melting point strong metal, such as steel, and the second metal is a lower-melting point, weaker, but lighter metal, such as aluminum.