Patents Assigned to Nanomimetics, Inc.
  • Methods of making and using surfactant polymers
    Patent number: 9125969
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: September 8, 2015
    Assignee: NANOMIMETICS, INC.
    Inventors: Jan J. Lewandowski, Yubiao Liu, Roger Marchant, Tianhong Zhang, Yongxing Qiu, Mark A. Ruegsegger
  • METHODS OF MAKING AND USING SURFACTANT POLYMERS
    Publication number: 20120245288
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 27, 2012
    Applicant: NANOMIMETICS, INC.
    Inventors: Jan J. LEWANDOWSKI, Yubiao LIU
  • Methods of making and using surfactant polymers
    Patent number: 8163302
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: April 24, 2012
    Assignee: NanoMimetics, Inc.
    Inventors: Roger E. Marchant, Tianhong Zhang, Yongxing Qiu, Mark A. Ruegsegger
  • METHODS OF MAKING AND USING SURFACTANT POLYMERS
    Publication number: 20080262614
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to the backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. Medical devices coated with the surfactant polymers are also provided. The surfactant polymers may be used to decrease the thrombogenic properties, encapsulation, and bacterial colonization of medical devices.
    Type: Application
    Filed: April 4, 2008
    Publication date: October 23, 2008
    Applicant: NANOMIMETICS, INC.
    Inventors: Roger E. MARCHANT, Jan J. LEWANDOWSKI, Yubiao LIU
  • Methods of making and using surfactant polymers
    Patent number: 7276474
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to said backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. The hydrophobic side chains comprise an alkyl group comprising from 2 to 18 methylene groups. The alkyl groups are linked to the polymeric backbone through ester linkages, secondary amine linkages, or, preferably, amide linkages.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: October 2, 2007
    Assignee: Nanomimetics, Inc.
    Inventors: Roger E. Marchant, Tianhong Zhang, Yongxing Qiu, Mark A. Ruegsegger
  • Surfactants that mimic the glycocalyx
    Patent number: 6759388
    Abstract: Comblike, surfactant polymers for changing the surface properties of biomaterials are provided. Such surfactant polymers comprise a polymeric backbone of repeating monomeric units having functional groups for coupling with side chains, a plurality of hydrophobic side chains linked to said backbone via the functional groups, and a plurality of hydrophilic side chains linked to said backbone via the functional groups. The hydrophobic side chains comprise an alkyl group comprising from 2 to 18 methylene groups. The alkyl groups are linked to the polymeric backbone through ester linkages, secondary amine linkages, or, preferably, amide linkages.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: July 6, 2004
    Assignee: Nanomimetics, Inc.
    Inventors: Roger E. Marchant, Tianhong Zhang, Yongxing Qiu, Mark A. Ruegsegger