Patents Assigned to NanoScale Corporation
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Publication number: 20130036908Abstract: Apparatus and methods for reducing or eliminating undesirable air-borne substances, such as odors, bacteria, viruses, fungi, and toxins, are provided. A filter containing nanocrystalline metal oxide or metal hydroxide particles may be installed within an air handling apparatus such as an existing HVAC unit located within a building, and particularly within a home, or a portable air processor or purifier. The air handling apparatus comprises a blower which pulls air containing various undesirable substances from within the enclosed environment and directs it through a filtering device containing the nanocrystalline particles. The undesirable substances are sorbed by the nanocrystalline particles thereby creating a deodorized stream of air that may then be directed back into various portions of the enclosed environment or vented to the atmosphere.Type: ApplicationFiled: October 17, 2012Publication date: February 14, 2013Applicant: NanoScale CorporationInventor: NanoScale Corporation
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Publication number: 20120157824Abstract: The present invention provides multifunctional nanoplatforms for assessing the activity of a protease in vivo or in vitro, along with methods of imaging and detecting the presence of cancerous or precancerous tissues, and the therapeutic treatment thereof, including monitoring of treatment. The diagnostic nanoplatforms comprise nanoparticles and are linked to each other or other particles via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected using various sensors, and the diagnostic results can be correlated with cancer prognosis. Individual unlinked nanoplatforms are also adaptable for therapeutic hyperthermia treatment of the cancerous tissue.Type: ApplicationFiled: August 31, 2010Publication date: June 21, 2012Applicants: NANOSCALE CORPORATION, KANSAS STATE UNIVERSITY RESEARCH FOUNDATIONInventors: Stefan H. Bossmann, Deryl Troyer, Matthew T. Basel, Thilani Nishanthika Samarakoon, Hongwang Wang, Viktor Chikan, Franklin Orban Kroh, Olga Barbara Koper, Brandon Ray Walker, Xiaoxuan Leaym
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Patent number: 8183426Abstract: The invention provides a sorptive sheet material in which finely divided nanocrystalline particles that react with a variety of chemical and/or biological agents are dispersed. The sheet material comprises a fibrous web that is formed of a plurality of fibers that are bonded to each other. The fibrous web contains a relatively high concentration of reactive nanocrystalline particles that are entrapped within the matrix of the fibrous web. Fluids containing toxic agents, such as chemical and/or biological agents, odors and/or odor causing compounds, and toxic industrial compounds, pass into the web and contact the reactive nanocrystalline particles contained therein. The reactive nanocrystalline particles react with, and chemically alter or inactivate the toxic agents. The sorptive sheet material may be used to construct containers, such as remains pouches, for the storing and transporting of contaminated items, particularly human remains.Type: GrantFiled: October 10, 2008Date of Patent: May 22, 2012Assignees: NanoScale Corporation, Kappler, Inc.Inventors: Jason R. Cole, Philip Mann, Shyamala Rajagopalan, Olga Koper
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Patent number: 8038935Abstract: Methods of removing odors, particularly odors within enclosed environments are provided which employ nanocrystalline metal oxide and metal hydroxide particles. The nanocrystalline particles are dispersed within an enclosed space so as to contact exposed surfaces located within the space such as walls, floors, upholstery, and the like and adsorb odor-causing materials located within the enclosed space.Type: GrantFiled: October 26, 2006Date of Patent: October 18, 2011Assignee: NanoScale CorporationInventors: Olga Koper, HaiDoo Kwen, Scott Toerber, Kyle Knappenberger, David Jones, Debbie Basco, Ken Klabunde, Bill Sanford
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Patent number: 7956232Abstract: Compositions and methods for destroying biological agents such as toxins and bacteria are provided wherein the substance to be destroyed is contacted with finely divided metal oxide or hydroxide nanocrystals. In various embodiments, the metal oxide or metal hydroxide nanocrystals have reactive atoms stabilized on their surfaces, species adsorbed on their surfaces, or are coated with a second metal oxide. The desired metal oxide or metal hydroxide nanocrystals can be pressed into pellets for use when a powder is not feasible. Preferred metal oxides for the methods include MgO, SrO, BaO, CaO, TiO2, ZrO2, FeO, V2O3, V2O5, Mn2O3, Fe2O3, NiO, CuO, Al2O3, SiO2, ZnO, Ag2O, [Ce(NO3)3—Cu(NO3)2]TiO2, Mg(OH)2, Ca(OH)2, Al(OH)3, Sr(OH)2, Ba(OH)2, Fe(OH)3, Cu(OH)3, Ni(OH)2, Co(OH)2, Zn(OH)2, AgOH, and mixtures thereof.Type: GrantFiled: January 2, 2008Date of Patent: June 7, 2011Assignee: NanoScale CorporationInventors: Olga Koper, Kenneth J. Klabunde, Lisa S. Martin, Kyle B. Knappenberger, Laura L. Hladky, Shawn P. Decker
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Publication number: 20100101413Abstract: Apparatus and methods for reducing or eliminating undesirable air-borne substances, such as odors, bacteria, viruses, fungi, and toxins, are provided. A filter containing nanocrystalline metal oxide or metal hydroxide particles may be installed within an air handling apparatus such as an existing HVAC unit located within a building, and particularly within a home, or a portable air processor or purifier. The air handling apparatus comprises a blower which pulls air containing various undesirable substances from within the enclosed environment and directs it through a filtering device containing the nanocrystalline particles. The undesirable substances are sorbed by the nanocrystalline particles thereby creating a deodorized stream of air that may then be directed back into various portions of the enclosed environment or vented to the atmosphere.Type: ApplicationFiled: August 26, 2009Publication date: April 29, 2010Applicant: NANOSCALE CORPORATIONInventors: David Jones, Kyle Knappenberger, Lincoln Mertz, Olga Koper, David Brotton, Deborah Basco, Bill Sanford
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Patent number: 7661483Abstract: Methods of reducing smoke levels in smoke-affected areas, reducing the level of toxic compounds produced by fires, fire suppression, and increasing flame retardancy. In particular, methods according to the present invention comprise dispersing nanocrystalline particles in the areas affected by smoke for sorption of smoke particulates and toxic compounds produced from a fire. The nanocrystalline particles are also effective for use in methods of fire suppression and flame retardancy.Type: GrantFiled: August 22, 2007Date of Patent: February 16, 2010Assignee: NanoScale CorporationInventors: Ravichandra S. Mulukutla, Paul S. Malchesky, Ronaldo Maghirang, John S. Klabunde, Kenneth J. Klabunde, Olga Koper
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Publication number: 20090260645Abstract: A tobacco product comprising nanocrystalline particles and methods of reducing the levels of undesirable compounds in tobacco smoke are provided. The nanocrystalline particles are effective sorbents of numerous toxic compounds released by burning tobacco and may be incorporated into the tobacco itself, incorporated into a filter element, or incorporated into the fibers of a wrapping paper.Type: ApplicationFiled: April 14, 2009Publication date: October 22, 2009Applicant: NANOSCALE CORPORATIONInventors: David Brotton, Olga B. Koper
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Patent number: 7566393Abstract: Compounds and methods for sorbing organosulfur compounds from fluids are provided. Generally, compounds according to the present invention comprise mesoporous, nanocrystalline metal oxides. Preferred metal oxide compounds either exhibit soft Lewis acid properties or are impregnated with a material exhibiting soft Lewis acid properties. Methods according to the invention comprise contacting a fluid containing organosulfur contaminants with a mesoporous, nanocrystalline metal oxide. In a preferred embodiment, nanocrystalline metal oxide particles are formed into pellets (14) and placed inside a fuel filter housing (12) for removing organosulfur contaminants from a hydrocarbon fuel stream.Type: GrantFiled: April 26, 2005Date of Patent: July 28, 2009Assignee: NanoScale CorporationInventors: Kenneth Klabunde, Bill R. Sanford, P. Jeevanandam
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Publication number: 20090118562Abstract: The invention provides a sorptive sheet material in which finely divided nanocrystalline particles that react with a variety of chemical and/or biological agents are dispersed. The sheet material comprises a fibrous web that is formed of a plurality of fibers that are bonded to each other. The fibrous web contains a relatively high concentration of reactive nanocrystalline particles that are entrapped within the matrix of the fibrous web. Fluids containing toxic agents, such as chemical and/or biological agents, odors and/or odor causing compounds, and toxic industrial compounds, pass into the web and contact the reactive nanocrystalline particles contained therein. The reactive nanocrystalline particles react with, and chemically alter or inactivate the toxic agents. The sorptive sheet material may be used to construct containers, such as remains pouches, for the storing and transporting of contaminated items, particularly human remains.Type: ApplicationFiled: October 10, 2008Publication date: May 7, 2009Applicants: NanoScale Corporation, Kappler, Inc.Inventors: Jason R. Cole, Philip Mann, Shyamala Rajagopalan, Olga Koper
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Publication number: 20090098016Abstract: Methods of removing odors, particularly odors within enclosed environments are provided which employ nanocrystalline metal oxide and metal hydroxide particles. The nanocrystalline particles are dispersed within an enclosed space so as to contact exposed surfaces located within the space such as walls, floors, upholstery, and the like and adsorb odor-causing materials located within the enclosed space.Type: ApplicationFiled: October 26, 2006Publication date: April 16, 2009Applicant: NANOSCALE CORPORATIONInventors: Olga Koper, HaiDoo Kwen, Scott Toerber, Kyle Knappenberger, David Jones, Debbie Basco, Ken Klabunde, Bill Sanford
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Publication number: 20080102136Abstract: Compositions and methods for destroying biological agents such as toxins and bacteria are provided wherein the substance to be destroyed is contacted with finely divided metal oxide or hydroxide nanocrystals. In various embodiments, the metal oxide or metal hydroxide nanocrystals have reactive atoms stabilized on their surfaces, species adsorbed on their surfaces, or are coated with a second metal oxide. The desired metal oxide or metal hydroxide nanocrystals can be pressed into pellets for use when a powder is not feasible. Preferred metal oxides for the methods include MgO, SrO, BaO, CaO, TiO2, ZrO2, FeO, V2O3, V2O5, Mn2O3, Fe2O3, NiO, CuO, Al2O3, SiO2, ZnO, Ag2O, [Ce(NO3)3—Cu(NO3)2]TiO2, Mg(OH)2, Ca(OH)2, Al(OH)3, Sr(OH)2, Ba(OH)2, Fe(OH)3, Cu(OH)3, Ni(OH)2, Co(OH)2, Zn(OH)2, AgOH, and mixtures thereof.Type: ApplicationFiled: January 2, 2008Publication date: May 1, 2008Applicant: NanoScale CorporationInventors: Olga Koper, Kenneth Klabunde, Lisa Martin, Kyle Knappenberger, Laura Hladky, Shawn Decker
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Patent number: 7341977Abstract: Compounds and methods for sorbing organosulfur compounds from fluids are provided. Generally, compounds according to the present invention comprise mesoporous, nanocrystalline metal oxides. Preferred metal oxide compounds either exhibit soft Lewis acid properties or are impregnated with a material exhibiting soft Lewis acid properties. Methods according to the invention comprise contacting a fluid containing organosulfur contaminants with a mesoporous, nanocrystalline metal oxide. In a preferred embodiment, nanocrystalline metal oxide particles are formed into pellets (14) and placed inside a fuel filter housing (12) for removing organosulfur contaminants from a hydrocarbon fuel stream.Type: GrantFiled: June 20, 2003Date of Patent: March 11, 2008Assignee: NanoScale CorporationInventors: Kenneth Klabunde, Bill R. Sanford, P. Jeevanandam
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Patent number: 7335808Abstract: Compositions and methods for destroying biological agents such as toxins and bacteria are provided wherein the substance to be destroyed is contacted with finely divided metal oxide or hydroxide nanocrystals. In various embodiments, the metal oxide or metal hydroxide nanocrystals have reactive atoms stabilized on their surfaces, species adsorbed on their surfaces, or are coated with a second metal oxide. The desired metal oxide or metal hydroxide nanocrystals can be pressed into pellets for use when a powder is not feasible. Preferred metal oxides for the methods include MgO, SrO, BaO, CaO, TiO2, ZrO2, FeO, V2O3, V2O5, Mn2O3, Fe2O3, NiO, CuO, Al2O3, SiO2, ZnO, Ag2O, [Ce(NO3)3—Cu(NO3)2]TiO2, Mg(OH)2, Ca(OH)2, Al(OH)3, Sr(OH)2, Ba(OH)2, Fe(OH)3, Cu(OH)3, Ni(OH)2, Co(OH)2, Zn(OH)2, AgOH, and mixtures thereof.Type: GrantFiled: September 9, 2003Date of Patent: February 26, 2008Assignee: NanoScale CorporationInventors: Olga Koper, Kenneth J. Klabunde, Lisa S. Martin, Kyle B. Knappenberger, Laura L. Hladky, Shawn P. Decker
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Publication number: 20070286796Abstract: An improved mixed metal oxide material suitable for use in electrochemical cells is provided. The mixed metal oxide material generally exhibits high surface area and pore volume than conventionally manufactured materials thereby imparting improved electrochemical performance. Batteries manufactured using the mixed metal oxide material are particularly suited for use in implantable medical devices.Type: ApplicationFiled: June 6, 2007Publication date: December 13, 2007Applicant: NANOSCALE CORPORATIONInventors: Olga Koper, Janis Voo, Slawomir Winecki, John Rasinski, Paul Malchesky, Kenneth Klabunde
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Patent number: 7279129Abstract: Metal oxide area decontamination apparatus (10) is provided which is designed for rapid, emergency situation decontamination of areas contaminated with potentially harmful or lethal chemical and/or biological warfare agents or other hazardous substances. The apparatus (10) preferably includes a pressurizable metallic container (12) equipped with a valve-type delivery nozzle assembly (16), so that upon a manipulation of the assembly (16), a spray of metal oxide and/or metal hydroxide particles is generated; the particles are selected and sized in order to destroy or chemisorb the contaminating agents. The preferred decontamination agent is MgO aggregated to an average aggregate size of from about 50 nm-10 microns. The particles are mixed with a gaseous or liquid propellant within the container (12) allowing rapid and thorough particle cleanout when the nozzle assembly (16) is actuated.Type: GrantFiled: June 2, 2003Date of Patent: October 9, 2007Assignee: NanoScale CorporationInventors: Bret E. Lanz, Thomas Allen
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Patent number: 7276640Abstract: Methods of reducing smoke levels in smoke-affected areas, reducing the level of toxic compounds produced by fires, fire suppression, and increasing flame retardancy. In particular, methods according to the present invention comprise dispersing nanocrystalline particles in the areas affected by smoke for sorption of smoke particulates and toxic compounds produced from a fire. The nanocrystalline particles are also effective for use in methods of fire suppression and flame retardancy.Type: GrantFiled: October 18, 2005Date of Patent: October 2, 2007Assignee: NanoScale CorporationInventors: Ravichandra S. Mulukutla, Paul S. Malchesky, Ronaldo Maghirang, John S. Klabunde, Kenneth J. Klabunde, Olga Koper