Patents Assigned to Nanostim, Inc.
  • Publication number: 20150297899
    Abstract: The invention relates to leadless cardiac pacemakers (LBS), and elements and methods by which they affix to the heart. The invention relates particularly to a secondary fixation of leadless pacemakers which also include a primary fixation. Secondary fixation elements for LBS's may passively engage structures within the heart. Some passive secondary fixation elements entangle or engage within intraventricular structure such as trabeculae carneae. Other passive secondary fixation elements may engage or snag heart structures at sites upstream from the chamber where the LBS is primarily affixed. Still other embodiments of passive secondary fixation elements may include expandable structures.
    Type: Application
    Filed: August 14, 2013
    Publication date: October 22, 2015
    Applicant: Nanostim, Inc.
    Inventor: Alan Ostroff
  • Publication number: 20140074114
    Abstract: A delivery system for implanting a leadless cardiac pacemaker into a patient is provided. The cardiac pacemaker can include a docking or delivery feature having a through-hole disposed on or near a proximal end of the pacemaker for attachment to the delivery system. In some embodiments, the delivery catheter can include first and second tethers configured to engage the delivery feature of the pacemaker. The tethers, when partially aligned, can have a cross-sectional diameter larger than the through-hole of the delivery feature, and when un-aligned, can have a cross-sectional diameter smaller than the through-hole of the delivery feature. Methods of delivering the leadless cardiac pacemaker with the delivery system are also provided.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 13, 2014
    Applicant: Nanostim, Inc.
    Inventors: Alexander Khairkhahan, Alan Klenk
  • Publication number: 20140058494
    Abstract: An active implantable medical device is disclosed herein having a radio-opaque marker. The radio-opaque marker can be formed within an exterior wall of the device or within recesses on the outside of the exterior wall. The implantable medical device can be a leadless pacemaker. The shape of the radio-opaque marker can be designed to facilitate visualization and identification of the location, orientation, and rotation of the implanted medical device by conventional fluoroscopy. Methods of use are also disclosed.
    Type: Application
    Filed: August 21, 2013
    Publication date: February 27, 2014
    Applicant: Nanostim, Inc.
    Inventors: Alan Ostroff, Paul Paspa, Peter M. Jacobson, Wade A. Keller, Christopher Alan Hubbard
  • Publication number: 20140039570
    Abstract: A leadless cardiac pacemaker is provided which can include any number of features. In one embodiment, the pacemaker can include a tip electrode, pacing electronics disposed on a p-type substrate in an electronics housing, the pacing electronics being electrically connected to the tip electrode, an energy source disposed in a cell housing, the energy source comprising a negative terminal electrically connected to the cell housing and a positive terminal electrically connected to the pacing electronics, wherein the pacing electronics are configured to drive the tip electrode negative with respect to the cell housing during a stimulation pulse. The pacemaker advantageously allows p-type pacing electronics to drive a tip electrode negative with respect to the can electrode when the can electrode is directly connected to a negative terminal of the cell. Methods of use are also provided.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Nanostim, Inc.
    Inventors: Kenneth J. Carroll, Alan Ostroff, Peter M. Jacobson
  • Publication number: 20140018876
    Abstract: A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained within the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises a temperature sensor hermetically contained within the housing and adapted to sense temperature information, wherein the pacemaker can control electrical pulse delivery at least partly based on the temperature information.
    Type: Application
    Filed: September 23, 2013
    Publication date: January 16, 2014
    Applicant: Nanostim, Inc.
    Inventor: Alan Ostroff
  • Patent number: 8543205
    Abstract: A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained within the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises a temperature sensor hermetically contained within the housing and adapted to sense temperature information, wherein the pacemaker can control electrical pulse delivery at least partly based on the temperature information.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: September 24, 2013
    Assignee: Nanostim, Inc.
    Inventor: Alan Ostroff
  • Patent number: 8527068
    Abstract: The invention relates to leadless cardiac pacemakers (LBS), and elements and methods by which they affix to the heart. The invention relates particularly to a secondary fixation of leadless pacemakers which also include a primary fixation. Secondary fixation elements for LBS's may passively engage structures within the heart. Some passive secondary fixation elements entangle or engage within intraventricular structure such as trabeculae carneae. Other passive secondary fixation elements may engage or snag heart structures at sites upstream from the chamber where the LBS is primarily affixed. Still other embodiments of passive secondary fixation elements may include expandable structures.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: September 3, 2013
    Assignee: Nanostim, Inc.
    Inventor: Alan Ostroff
  • Patent number: 8457742
    Abstract: A cardiac pacing system comprising one or more leadless cardiac pacemakers configured for implantation in electrical contact with a cardiac chamber and configured to perform cardiac pacing functions in combination with a co-implanted implantable cardioverter-defibrillator (ICD). The leadless cardiac pacemaker comprises at least two leadless electrodes configured for delivering cardiac pacing pulses, sensing evoked and/or natural cardiac electrical signals, and bidirectionally communicating with the co-implanted ICD.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: June 4, 2013
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 8352025
    Abstract: A leadless cardiac pacemaker configured for implantation in electrical contact with a left ventricular cardiac chamber and configured for leadless triggered left-ventricular pacing for cardiac resynchronization therapy (CRT) in response to conducted signals from a pulse generator.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: January 8, 2013
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 8295939
    Abstract: A biostimulator system comprises one or more implantable devices and an external programmer configured for communicating with the implantable device or devices via bidirectional communication pathways comprising a receiving pathway that decodes information encoded on stimulation pulses generated by ones of the implantable device or devices and conducted through body tissue to the external programmer.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: October 23, 2012
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Publication number: 20110282423
    Abstract: A delivery system for implanting a biostimulation device comprising a stylet extending along an axis from knob end to a threaded end configured to engage an internally threaded nut of the biostimulation device and a catheter tube configured to axially contain the stylet. The catheter tube comprises a feature that engages a corresponding feature on the biostimulation device whereby the stylet can be rotated relative to the catheter tube for disengagement of the stylet threaded end from the biostimulation device threaded end.
    Type: Application
    Filed: July 26, 2011
    Publication date: November 17, 2011
    Applicant: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Publication number: 20110218587
    Abstract: A biostimulator system comprises one or more implantable devices and an external programmer configured for communicating with the implantable device or devices via bidirectional communication pathways comprising a receiving pathway that decodes information encoded on stimulation pulses generated by ones of the implantable device or devices and conducted through body tissue to the external programmer.
    Type: Application
    Filed: May 17, 2011
    Publication date: September 8, 2011
    Applicant: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 8010209
    Abstract: A delivery system for implanting a biostimulation device comprising a stylet extending along an axis from knob end to a threaded end configured to engage an internally threaded nut of the biostimulation device and a catheter tube configured to axially contain the stylet. The catheter tube comprises a feature that engages a corresponding feature on the biostimulation device whereby the stylet can be rotated relative to the catheter tube for disengagement of the stylet threaded end from the biostimulation device threaded end.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: August 30, 2011
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Publication number: 20110208260
    Abstract: A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained within the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises an activity sensor hermetically contained within the housing and adapted to sense activity and a processor hermetically contained within the housing and communicatively coupled to the pulse delivery system, the activity sensor, and the electrode plurality, the processor configured to control electrical pulse delivery at least partly based on the sensed activity.
    Type: Application
    Filed: April 29, 2011
    Publication date: August 25, 2011
    Applicant: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 7945333
    Abstract: A biostimulator system comprises one or more implantable devices and an external programmer configured for communicating with the implantable device or devices via bidirectional communication pathways comprising a receiving pathway that decodes information encoded on stimulation pulses generated by ones of the implantable device or devices and conducted through body tissue to the external programmer.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: May 17, 2011
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Patent number: 7937148
    Abstract: A leadless cardiac pacemaker comprises a housing, a plurality of electrodes coupled to an outer surface of the housing, and a pulse delivery system hermetically contained with the housing and electrically coupled to the electrode plurality, the pulse delivery system configured for sourcing energy internal to the housing, generating and delivering electrical pulses to the electrode plurality. The pacemaker further comprises an activity sensor hermetically contained within the housing and adapted to sense activity and a processor hermetically contained within the housing and communicatively coupled to the pulse delivery system, the activity sensor, and the electrode plurality, the processor configured to control electrical pulse delivery at least partly based on the sensed activity.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: May 3, 2011
    Assignee: Nanostim, Inc.
    Inventor: Peter M. Jacobson
  • Publication number: 20110071586
    Abstract: A leadless cardiac pacemaker configured for implantation in electrical contact with a left ventricular cardiac chamber and configured for leadless triggered left-ventricular pacing for cardiac resynchronization therapy (CRT) in response to conducted signals from a pulse generator.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 24, 2011
    Applicant: Nanostim, Inc.
    Inventor: Peter M. Jacobson