Patents Assigned to NAPIGEN, INC.
  • Organelle genome modification using polynucleotide guided endonuclease
    Patent number: 12173295
    Abstract: Provided herein are methods and systems for altering the genome of an organelle. In some embodiments, the method comprises introducing into an organelle a recombinant DNA construct comprising a first polynucleotide encoding at least one guide RNA and a second polynucleotide encoding a polynucleotide guided polypeptide; and growing a cell comprising the organelle under conditions in which the first polynucleotide and the second polynucleotide are each expressed.
    Type: Grant
    Filed: January 19, 2024
    Date of Patent: December 24, 2024
    Assignee: NAPIGEN, INC.
    Inventors: Hajime Sakai, Byung-Chun Yoo, Emil Meyer Orozco, Jr., Ganesh Kishore, Narendra Singh Yadav
  • Organelle genome modification using polynucleotide guided endonuclease
    Patent number: 11920140
    Abstract: Provided herein are methods and systems for altering the genome of an organelle. In some embodiments, the method comprises introducing into an organelle a recombinant DNA construct comprising a first polynucleotide encoding at least one guide RNA and a second polynucleotide encoding a polynucleotide guided polypeptide; and growing a cell comprising the organelle under conditions in which the first polynucleotide and the second polynucleotide are each expressed.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: March 5, 2024
    Assignee: NAPIGEN, INC.
    Inventors: Hajime Sakai, Byung-Chun Yoo, Emil Meyer Orozco, Jr., Ganesh Kishore, Narendra Singh Yadav