Patents Assigned to NASHPHARM
  • Patent number: 11185520
    Abstract: A composition comprising, as an active principle, a pharmaceutically acceptable salt of elafibranor, characterised in that the pharmaceutically acceptable salt of elafibranor is chosen from at least a salt of choline, of ethanolamine, or of diethanolamine, or of L-lysine, or of piperazine, or of calcium, or of tromethamine. More particularly, one or more embodiments relate to the use of elafibranor salts with a view to improving stability and solubility compared with elafibranor in the basic form thereof. These salts make it possible to establish pharmaceutical formulations in various advantageous forms as intravenous injections or formulations by enteral route having quicker and less variable absorption and consequently better bioavailability.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: November 30, 2021
    Assignee: NASHPHARM
    Inventors: Claude Laruelle, Ludovic Bonnafous