Patents Assigned to National Cancer Center
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Publication number: 20230091956Abstract: The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the miRNA in vitro.Type: ApplicationFiled: September 8, 2022Publication date: March 23, 2023Applicants: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Junpei KAWAUCHI, Hitoshi NOBUMASA, Satoko KOZONO, Satoshi KONDOU, Hiroko SUDO, Atsushi OCHIAI, Motohiro KOJIMA
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Publication number: 20230091147Abstract: It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit or a device for the detection of breast cancer, comprising nucleic acid(s) capable of specifically binding to a miRNA in a sample of a subject, and a method for detecting breast cancer, comprising measuring the miRNA in vitro.Type: ApplicationFiled: September 14, 2022Publication date: March 23, 2023Applicants: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoshi KONDOU, Hitoshi NOBUMASA, Satoko KOZONO, Hiroko SUDO, Junpei KAWAUCHI, Takahiro OCHIYA, Nobuyoshi KOSAKA, Makiko ONO, Kenji TAMURA
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Publication number: 20230087570Abstract: The present invention relates to a monoclonal antibody or antigen-binding fragment thereof that specifically binds to TIM-3 and uses thereof. The monoclonal antibody, hTIM-3_NCC1, of the present invention specifically recognizes human and mouse cells expressing TIM-3, and it can be useful for various fields such as diagnosis of diseases mediated by TIM-3 expressing cells as well as prevention or treatment thereof.Type: ApplicationFiled: February 25, 2021Publication date: March 23, 2023Applicant: NATIONAL CANCER CENTERInventor: Eun Jung PARK
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Publication number: 20230082982Abstract: A suture method includes a first arrangement step of using a first treatment device including first/second grasping pieces to hook the first grasping piece to a first position of peripheral tissues of a lesion; a second arrangement step of hooking the second grasping piece to a second position of the peripheral tissues; a grasping step of grasping the first position and the second position while pressing the first position and the second position to the peripheral tissues; a retracting step of retracting the lesion site toward a proximal end side of the first treatment device while drawing the first position and the second position grasped by the first treatment device; and a suturing step of suturing a first suturing position at an external side of the first position and a second suturing position at an external side of the second position in the peripheral tissues.Type: ApplicationFiled: September 10, 2021Publication date: March 16, 2023Applicants: OLYMPUS CORPORATION, NATIONAL CANCER CENTERInventors: Chisato KARASAWA, Satoru NONAKA, Ichiro ODA
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Patent number: 11603519Abstract: Provided is a T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24. A T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 28 or a complex of the peptide and HLA-A02. Disclosed T cell receptors are useful in treating or avoiding cancers which are associated with expression of glypican-3.Type: GrantFiled: February 5, 2018Date of Patent: March 14, 2023Assignees: National Cancer Center Japan, Kyoto University, Takeda Pharmaceutical Company LimitedInventors: Tetsuya Nakatsura, Toshiaki Yoshikawa, Yasushi Uemura, Kyoko Fukuda, Shin Kaneko, Atsutaka Minagawa, Yoshiaki Kassai, Atsushi Matsuda
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Publication number: 20230070866Abstract: A method for producing a professional antigen-presenting cell, including inducing expression of c-MYC, BMI1, and MDM2 in a myeloid cell (MC) to obtain a proliferative myeloid cell (pMC), and inducing expression of GM-CSF and/or M-CSF in the pMC to obtain a professional antigen-presenting cell (pAPC). The myeloid cell is a myeloid cell differentiated from a pluripotent stem cell.Type: ApplicationFiled: November 10, 2022Publication date: March 9, 2023Applicants: AGC INC., National Cancer Center JapanInventors: Yuichiro HAGIYA, Yasushi UEMURA, Kyoko FUKUDA, Tatsuaki IWAMA
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Patent number: 11553829Abstract: An information processing apparatus (2000) detects an abnormal region (30) from a predetermined range (16) of a video frame (14). The information processing apparatus (2000) determines whether a predetermined condition is satisfied in a case where the abnormal region (30) is detected from the predetermined range (16) of a certain video frame (14) and the abnormal region (30) is not detected from the predetermined range (16) of a predetermined video frame (14) generated later than the video frame (14). In a case where the predetermined condition is not satisfied, the information processing apparatus (2000) performs a predetermined notification.Type: GrantFiled: May 18, 2018Date of Patent: January 17, 2023Assignees: NEC CORPORATION, NATIONAL CANCER CENTERInventors: Ikuma Takahashi, Maki Sano, Motoyasu Okutsu, Chiemi Tanaka, Masahiro Saikou, Hitoshi Imaoka, Kenichi Kamijo, Yutaka Saito, Masayoshi Yamada
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Publication number: 20230002836Abstract: Disclosed is a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer, including a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting stomach cancer, including measuring the miRNA(s) in vitro.Type: ApplicationFiled: September 20, 2022Publication date: January 5, 2023Applicants: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoko KOZONO, Hitoshi NOBUMASA, Satoshi KONDOU, Hiroko SUDO, Junpei KAWAUCHI, Atsushi OCHIAI, Motohiro KOJIMA
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Patent number: 11542558Abstract: It is intended to provide a kit or a device for the detection of esophageal cancer and a method for detecting esophageal cancer. The present invention provides a kit or a device for the detection of esophageal cancer, comprising nucleic acid(s) capable of specifically binding to miRNA(s) in a sample f a subject, and a method for detecting esophageal cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: February 27, 2020Date of Patent: January 3, 2023Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Hiroko Sudo, Hitoshi Nobumasa, Satoko Kozono, Satoshi Kondou, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Patent number: 11535899Abstract: This invention provides a kit or device for detection of prostate cancer and a method for detecting prostate cancer. This invention provides a kit or device for detection of prostate cancer comprising a nucleic acid capable of specifically binding to an miRNA in a sample from a subject or a complementary strand thereof and a method for detecting prostate cancer comprising measuring the miRNA in vitro.Type: GrantFiled: August 9, 2019Date of Patent: December 27, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Makiko Yoshimoto, Hiroko Sudo, Atsuko Miyano, Satoko Kozono, Takahiro Ochiya, Hiroyuki Fujimoto, Fumihiko Urabe, Juntaro Matsuzaki
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Publication number: 20220398728Abstract: There is disclosed a non-transitory computer-readable recording medium having stored therein an information processing program for causing a computer to execute a process.Type: ApplicationFiled: May 27, 2022Publication date: December 15, 2022Applicants: FUJITSU LIMITED, RIKEN, NATIONAL CANCER CENTERInventors: Akira SAKAI, Masaaki KOMATSU, Kanto SHOZU
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Publication number: 20220398727Abstract: A non-transitory computer-readable recording medium has stored therein an evaluating program for causing a computer to execute a process including: specifying a wall of an inspection target in two or more moving images being obtained by photographing two types of cross sections of the inspection target, the two types of cross sections being orthogonal to each other; evaluating photographing quality of each of a plurality of first divisional regions obtained by dividing a region corresponding to the wall specified in a first image related to a first cross section among the two or more moving images; and evaluating photographing quality of each of a plurality of second divisional regions obtained by dividing a region corresponding to the wall specified in a second image related to a second cross section among the two or more moving images, the second cross section being different from the first cross section.Type: ApplicationFiled: May 27, 2022Publication date: December 15, 2022Applicants: FUJITSU LIMITED, RIKEN, National University Corporation Tokyo Medical and Dental University, NATIONAL CANCER CENTERInventors: Akira SAKAI, Masaaki KOMATSU, Tetsuo SASANO, Hideki ARIMA, Ryuji HAMAMOTO
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Patent number: 11524074Abstract: An object of the present invention is to provide an anticancer drug capable of treating cancer by finding a target molecule specifically expressed in cancer cells and by specifically acting on the target molecule, and to provide a cancer testing method including a step of measuring the target molecule in a sample. The present invention provides an anticancer drug containing, as an active ingredient thereof, an anti-transmembrane protein 180 (TMEM-180) antibody or an antigen-binding fragment thereof. In addition, the present invention provides a cancer testing method including a step of measuring the amount of TMEM-180 in a sample collected from a subject.Type: GrantFiled: September 23, 2019Date of Patent: December 13, 2022Assignees: National Cancer Center, RIN Institute Inc.Inventors: Yasuhiro Matsumura, Masahiro Yasunaga, Shinji Saijou, Shingo Hanaoka
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Patent number: 11519038Abstract: An object of the present invention is to provide a kit or a device for the detection of prostate cancer and a method for detecting prostate cancer. The present invention provides a kit or a device for the detection of prostate cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample of a subject, and a method for detecting prostate cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: March 3, 2020Date of Patent: December 6, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoshi Kondou, Hitoshi Nobumasa, Satoko Kozono, Hiroko Sudo, Junpei Kawauchi, Takahiro Ochiya, Nobuyoshi Kosaka
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Patent number: 11519927Abstract: It is intended to provide a kit or a device for the detection of lung cancer and a method for detecting lung cancer. The present invention provides a kit or a device for the detection of lung cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting lung cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: February 25, 2020Date of Patent: December 6, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Hiroko Sudo, Hitoshi Nobumasa, Satoko Kozono, Satoshi Kondou, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Patent number: 11512355Abstract: It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting liver cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: February 7, 2020Date of Patent: November 29, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoshi Kondou, Hitoshi Nobumasa, Satoko Kozono, Hiroko Sudo, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Patent number: 11508064Abstract: A method includes: acquiring a training data set including pieces of training data, each of the pieces including an image of a training target, first annotation data representing a rectangular region in the image, and second annotation data; training, based on the image and the first annotation data, an object detection model specifying a rectangular region including the training target; training, based on the image and the second annotation data, a neural network; and calculating a first index value related to a relationship of a pixel number, the trained estimation model and the calculated first index value being used in a determination process that determines, based on the calculated first index value and a second index value relationship between a pixel number in an output result and an estimation result, whether or not a target in a target image is normal.Type: GrantFiled: January 8, 2021Date of Patent: November 22, 2022Assignees: FUJITSU LIMITED, RIKEN, NATIONAL CANCER CENTERInventors: Akira Sakai, Masaaki Komatsu, Ai Dozen
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Patent number: 11499198Abstract: The present invention provides a kit or device for the detection of biliary tract cancer, and a method for detecting biliary tract cancer. The present invention relates to a kit or device for the detection of biliary tract cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting biliary tract cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: March 18, 2020Date of Patent: November 15, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Junpei Kawauchi, Hitoshi Nobumasa, Satoko Kozono, Satoshi Kondou, Hiroko Sudo, Atsushi Ochiai, Motohiro Kojima
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Patent number: 11486009Abstract: This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer, comprising a nucleic acid(s) capable of specifically binding to a miRNA(s) in a sample from a subject, and a method for detecting stomach cancer, comprising measuring the miRNA(s) in vitro.Type: GrantFiled: February 13, 2020Date of Patent: November 1, 2022Assignees: Toray Industries, Inc., National Cancer CenterInventors: Satoko Kozono, Hitoshi Nobumasa, Satoshi Kondou, Hiroko Sudo, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Patent number: 11479822Abstract: It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit or a device for the detection of breast cancer, comprising nucleic acid(s) capable of specifically binding to a miRNA in a sample of a subject, and a method for detecting breast cancer, comprising measuring the miRNA in vitro.Type: GrantFiled: February 21, 2020Date of Patent: October 25, 2022Assignees: TORAY INDUSTRIES, INC., NATIONAL CANCER CENTERInventors: Satoshi Kondou, Hitoshi Nobumasa, Satoko Kozono, Hiroko Sudo, Junpei Kawauchi, Takahiro Ochiya, Nobuyoshi Kosaka, Makiko Ono, Kenji Tamura