Patents Assigned to National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention
  • Broadly neutralizing antibodies against HIV-1 and use thereof
    Patent number: 10934345
    Abstract: Broadly neutralizing antibodies against HIV-1 which specifically bind to gp120 of HIV-1, a method of preparing such antibodies and the use thereof are provided.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: March 2, 2021
    Assignees: NATIONAL CENTER FOR AIDS/STD CONTROL AND PREVENTION, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Yiming Shao, Jiang Zhu, Yuxing Li, Ian A. Wilson, Leopold Kong, Bin Ju, Linling He, Li Ren, Yajing Chen, Jiandong Liu
  • Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine
    Patent number: 10251948
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: April 9, 2019
    Assignee: National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Anti-HIV vaccine constructed based on amino acid mutations in attenuated live EIAV vaccine
    Patent number: 8956620
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: February 17, 2015
    Assignee: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen