Patents Assigned to NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
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Publication number: 20210293704Abstract: A method for quality evaluation includes emitting measurement light having a wavelength of 300 nm or more and 2,000 nm or less to a cell mass and acquiring a plurality of light intensity information corresponding to each of a plurality of measuring positions in the cell mass, generating a feature amount from a variation of the acquired plurality of light intensity information, and evaluating quality of the cell mass using the generated feature amount as an index.Type: ApplicationFiled: June 4, 2021Publication date: September 23, 2021Applicants: Sumitomo Electric Industries, Ltd., Cyfuse Biomedical K.K., National University Corporation Tokai National Higher Education and Research SystemInventors: Asako MOTOMURA, Yoko SUGIYAMA, Hiroshi SUGANUMA, Akinori KIMURA, Shizuka AKIEDA, Yudai MIYAZAKI, Ryuji KATO, Mayu SHIBUTA, Ryohei YAMAMOTO
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Patent number: 11118898Abstract: A method for producing a preparation for fiber length measurement includes: a preliminary dispersion process of adding fibers and a dispersion medium with a viscosity of 500 Pa·s to 10,000 Pa·s to a sealable container so as to give a concentration of the fibers of 0.1% by mass or less and shaking the container to prepare a preliminary dispersion liquid; a dispensing process of dispensing part of the preliminary dispersion liquid to another sealable container; a dilution process of adding the dispersion medium to the dispensed preliminary dispersion liquid so as to give a concentration of the fibers of 0.005% by mass or less and shaking the container to prepare a dispersion liquid for measuring fiber length; and a casting process of spreading part of the dispersion liquid for measuring fiber length onto a base having light transparency.Type: GrantFiled: October 2, 2018Date of Patent: September 14, 2021Assignees: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, TORAY INDUSTRIES, INC., AISIN SEIKI KABUSHIKI KAISHA, KYOWA INDUSTRIAL CO., LTDInventors: Mariko Terada, Atsuhiko Yamanaka, Yukitane Kimoto, Koji Shiraki, Yuji Hotta, Daisuke Shimamoto
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Publication number: 20210263089Abstract: A measurement probe used in an electromagnetic wave measurement system is provided. The measurement probe includes a first measurement device and a second measurement device. The first measurement device includes a first electro-optic crystal that exhibits an electro-optic effect, a first optical fiber that is provided on a root side of the first electro-optic crystal and transmits an optical signal, and a first reflector that is provided on a tip side of the first electro-optic crystal and reflects the optical signal. The second measurement device includes a second electro-optic crystal, a second optical fiber, and a second reflector. The first and second electro-optic crystals form one electro-optic crystal, and the first and second optical fibers are connected to a root side of the one electro-optic crystal.Type: ApplicationFiled: May 6, 2021Publication date: August 26, 2021Applicants: Think-Lands Co., Ltd., NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Shintaro HISATAKE, Yoichi Oikawa, Kunio Miyaji, Makoto Tojo
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Publication number: 20210256312Abstract: An anomaly detection apparatus comprises a pattern storage part, first long time-span feature extraction part, a pattern feature calculation part, and a score calculation part. The pattern storage part stores a signal pattern model trained based on an acoustic signal for training in a first time-span and a feature for training being calculated from signal for training in a second time-span that is longer than first time-span. The first long time-span feature extraction part extracts a long time-span feature for detection associated with the feature for training from a signal being a detection target. The pattern feature calculation part calculates a signal pattern feature related to a signal being a detection target based on the signal being a detection target, the feature for detection, and the signal pattern model. The score calculation part calculates score to detect anomaly in the signal being detection target.Type: ApplicationFiled: May 18, 2018Publication date: August 19, 2021Applicants: NEC CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Tatsuya KOMATSU, Reishi KONDO, Tomoki HAYASHI
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Publication number: 20210253430Abstract: The present disclosure relates to methods for depositing vertically oriented carbon nanowalls (CNWs) using non-equilibrium gases such as gaseous plasma. Methods are disclosed for rapid deposition of uniformly distributed nanowalls on large surfaces of substrates using ablation of bulk carbon materials by reactive gaseous species, formation of oxidized carbon-containing gaseous molecules, ionization of said molecules and interacting said molecules, neutral or positively charged, with a substrate. The CNWs prepared are useful in different applications such as fuel cells, lithium ion batteries, photovoltaic devices and sensors of specific gaseous molecules.Type: ApplicationFiled: June 11, 2018Publication date: August 19, 2021Applicants: Jozef Stefan Institute, NATIONAL UNIVERSTIY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Rok ZAPLOTNIK, Miran Mozetic, Gregor PRIMC, Alenka VESEL, Masaru HORI
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Publication number: 20210236463Abstract: An object is to provide a compound having ?-lactamase inhibitory activity. The object is achieved by a compound represented by formula (1), typified by a compound in which specific positions of a 5-membered ring having planarity are replaced by sulfamoyl and carboxy groups.Type: ApplicationFiled: May 14, 2019Publication date: August 5, 2021Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Yoshichika ARAKAWA, Jun-ichi WACHINO, Kouji KIMURA, Wan Chun JIN, Ayato SATO
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Publication number: 20210230598Abstract: The present invention provides a tau exon 10 skipping-promoting antisense oligonucleotide containing at least one 2?-O, 4?-C-ethylene-bridged nucleic acid, and a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a region consisting of the nucleotide sequence shown in SEQ ID NO: 44 in exon 10 of a tau mRNA precursor. In addition, the present invention provides a tau exon 10 skipping-suppressing antisense oligonucleotide containing at least one 2?-O, 4?-C-ethylene-bridged nucleic acid, and a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a region consisting of the nucleotide sequence shown in SEQ ID NO: 45 in intron 10 of a tau mRNA precursor.Type: ApplicationFiled: July 3, 2019Publication date: July 29, 2021Applicants: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, KNC LABORATORIES CO., LTD.Inventors: Gen SOBUE, Kentaro SAHASHI, Shinsuke ISHIGAKI, Kuniyuki ENDO, Tsuyoshi FUJIHARA, Masahiro NEYA, Seiji MATSUDA
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Publication number: 20210230336Abstract: The present invention provides a block copolymer composition comprising a block copolymer B formed by introducing a functional group capable of forming a non-covalent bond into a block copolymer A including at least one aromatic vinyl polymer block and at least one conjugated diene polymer block, wherein: the block copolymer B includes an ionic group as the functional group capable of forming a non-covalent bond.Type: ApplicationFiled: April 25, 2019Publication date: July 29, 2021Applicants: ZEON CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Kousuke ISOBE, Sadaharu HASHIMOTO, Atsushi NORO, Takato KAJITA, Haruka TANAKA, Yushu MATSUSHITA
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Publication number: 20210210924Abstract: An object of the present invention is to provide a method for manufacturing an optical device having a laser diode, which method is suitable for mass production, and an optical device having a laser diode which allows accurate property evaluations thereof with small measurement errors. Specifically, the method includes: an etching process of etching a semiconductor lamination unit to form a mesa structure having a resonator end face, thereby forming a laser diode; and a reflecting layer forming process of forming a light reflecting layer such that the light reflecting layer covers entire side surfaces of the mesa structure, wherein the semiconductor lamination unit has a substate, a n-type clad layer including a nitride semiconductor layer having n-type conductivity, a light-emitting layer including at least one quantum well, and a p-type clad layer including a nitride semiconductor layer having p-type conductivity, laminated in this order.Type: ApplicationFiled: January 5, 2021Publication date: July 8, 2021Applicants: ASAHI KASEI KABUSHIKI KAISHA, National University Corporation Tokai National Higher Education and Research SystemInventors: Ziyi ZHANG, Maki KUSHIMOTO, Hiroshi AMANO
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Publication number: 20210179936Abstract: Semiconductor nanoparticles are provided. The semiconductor nanoparticles contains Ag, at least one of In and Ga, and Se. An Ag content is 10 mol % to 30 mol %, a total content of the at least one of In and Ga is 15 mol % to 35 mol %, and an Se content is 35 mol % to 55 mol % in the semiconductor nanoparticles. The semiconductor nanoparticles emit light having an emission spectrum with a peak emission wavelength in a range of 500 nm to 900 nm, and a half bandwidth of 250 meV or less upon irradiation with light in a wavelength range of 350 nm to less than 500 nm.Type: ApplicationFiled: February 16, 2021Publication date: June 17, 2021Applicants: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, OSAKA UNIVERSITY, NICHIA CORPORATIONInventors: Tsukasa TORIMOTO, Tatsuya KAMEYAMA, Hiroki YAMAUCHI, Chie MIYAMAE, Yuki MORI, Susumu KUWABATA, Taro UEMATSU, Daisuke OYAMATSU
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Patent number: 10954439Abstract: A method of producing semiconductor nanoparticles, semiconductor nanoparticles, and a light-emitting device are provided. The method includes heat-treating a mixture containing a salt of Ag, a salt containing at least one of In and Ga, an Se supply source, and an organic solvent at a temperature in the range of above 200° C. to 370° C. In the method, the ratio of the number of Ag atoms to the total number of In and Ga atoms in the mixture is above 0.43 to 2.5. The semiconductor nanoparticles contains Ag, at least one of In and Ga, and Se. The light-emitting device includes a light conversion member containing the semiconductor nanoparticles and a semiconductor light-emitting element.Type: GrantFiled: May 9, 2019Date of Patent: March 23, 2021Assignees: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION and RESEARCH SYSTEM, OSAKA UNIVERSITY, NICHIA CORPORATIONInventors: Tsukasa Torimoto, Tatsuya Kameyama, Hiroki Yamauchi, Chie Miyamae, Yuki Mori, Susumu Kuwabata, Taro Uematsu, Daisuke Oyamatsu
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Publication number: 20210078975Abstract: The present invention relates to fused cyclic urea derivatives which have antagonistic activities against CRHR1 and/or CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR1 and/or CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR1 and/or CRHR2 is involved.Type: ApplicationFiled: April 9, 2019Publication date: March 18, 2021Applicants: RaQualia Pharma Inc., National University Corporation Tokai National Higher Education and Research SystemInventors: Masashi OHMI, Takeshi MATSUSHITA, Kazuo ANDO, Ryuichi YAMAGUCHI, Yutaka FUKUMOTO, Ryohei MAGARA, Tatsuya YAMAGISHI, Mikito TAKEFUJI
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Publication number: 20210083146Abstract: Provided is a method of producing semiconductor nanoparticles that exhibit a band-edge emission, and are superior in quantum yield. The method includes raising the temperature of a first mixture containing a silver (Ag) salt, a salt containing at least one of indium (In) and gallium (Ga), a solid compound that serves as a supply source of sulfur (S), and an organic solvent to a temperature in a range of from 125° C. to 175° C., and heat-treating, subsequent to the raising of the temperature, the first mixture at a temperature in a range of from 125° C. to 175° C. for three seconds or more to obtain a solution containing semiconductor nanoparticles, and decreasing the temperature of the solution containing semiconductor nanoparticles. The solid compound that serves as a supply source of S contains thiourea.Type: ApplicationFiled: February 15, 2019Publication date: March 18, 2021Applicants: OSAKA UNIVERSITY, National University Corporation Tokai National Higher Education and Research System, NICHIA CORPORATIONInventors: Susumu KUWABATA, Taro UEMATSU, Kazutaka WAJIMA, Tsukasa TORIMOTO, Tatsuya KAMEYAMA, Daisuke OYAMATSU
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Publication number: 20210053830Abstract: A carbon nanosheet, which is a sheet-form carbon nanomaterial having a larger area as compared with that of a similar conventional product and a side length of about 1 ?m, and a method for producing the carbon nanosheet. The carbon nanosheet production method includes a step of mixing a solution of an iron atom-containing compound dispersed in a solvent with an alcohol, to thereby prepare a solution mixture; and a step of irradiating the solution mixture with plasma, to thereby produce a carbon nanosheet. The carbon nanosheet has a side length of 0.5 ?m to 2.5 ?m.Type: ApplicationFiled: December 25, 2018Publication date: February 25, 2021Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Masaru HORI, Hiroki KONDO, Kenji ISHIKAWA
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Publication number: 20210040385Abstract: Provided are core-shell semiconductor nanoparticles, each including a core and a shell disposed on a surface of the core, and emitting light when irradiated with light. The core contains a semiconductor containing M1, M2, and Z, M1 containing at least one selected from the group consisting of Ag, Cu, and Au, M2 containing at least one selected from the group consisting of Al, Ga, In, and Tl, and Z containing at least one selected from the group consisting of S, Se, and Te. The shell contains a semiconductor containing a Group 13 element and a Group 16 element, and having a greater band-gap energy than the core. The shell has a compound containing a Group 15 element disposed on a surface of the shell, and the Group 15 element containing at least P with a negative oxidation number.Type: ApplicationFiled: February 15, 2019Publication date: February 11, 2021Applicants: OSAKA UNIVERSITY, National University Corporation Tokai National Higher Education and Research System, NICHIA CORPORATIONInventors: Susumu KUWABATA, Taro UEMATSU, Kazutaka WAJIMA, Tsukasa TORIMOTO, Tatsuya KAMEYAMA, Daisuke OYAMATSU
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Publication number: 20210037637Abstract: An atomic beam generator includes a cathode constituted as a housing having an emission surface provided with an irradiation port through which an atomic beam is emissive; an anode disposed inside the cathode to generate plasma between the cathode and the anode; and a magnetic field generating unit including a first magnetic field generating unit that generates a first magnetic field and a second magnetic field generating unit that generates a second magnetic field, and guiding positive ions produced in the cathode to the emission surface by generating, in the cathode, the first magnetic field and the second magnetic field both parallel to the emission surface such that a magnetic field direction is leftward in the first magnetic field and is rightward in the second magnetic field when viewed from an emission surface side on condition of the first magnetic field being positioned above the second magnetic field.Type: ApplicationFiled: October 16, 2020Publication date: February 4, 2021Applicants: National University Corporation Tokai National Higher Education and Research System, NGK Insulators, Ltd.Inventors: Seiichi HATA, Junpei SAKURAI, Yuuki HIRAI, Hiroyuki TSUJI, Takayoshi AKAO, Tomoki NAGAE, Tomonori TAKAHASHI
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Publication number: 20210033312Abstract: A heat exchanger includes: a low temperature side channel through which low temperature liquid helium flows; a high temperature side channel through which high temperature liquid helium flows; and a thermal conduction unit that conducts heat from the high temperature side channel to the low temperature side channel. The thermal conduction unit has a partition member that separates the high temperature side channel and the low temperature side channel from each other and a thermal resistance reduction unit that reduces the thermal resistance between the partition member and the liquid helium. The thermal resistance reduction unit has a porous body having nano-size pores and fine metal particles having higher thermal conductivity than that of the porous body.Type: ApplicationFiled: February 25, 2019Publication date: February 4, 2021Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Nobuo Wada, Taku Matsushita, Mitsunori Hieda
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Publication number: 20210016226Abstract: A gas treatment method includes an absorption step in which a gas to be treated containing an acidic compound, such as carbon dioxide, is brought into contact, in an absorber, with a treatment liquid that absorbs the acidic compound; and a regeneration step in which the treatment liquid, having the acidic compound absorbed therein, is sent to a regenerator, and the treatment liquid is then heated to separate the acidic compound from the treatment liquid. In the regeneration step, a gas almost insoluble to the treatment liquid, such as hydrogen gas, is brought into contact with the treatment liquid.Type: ApplicationFiled: November 12, 2018Publication date: January 21, 2021Applicants: KABUSHIKI KAISHA KOBE SEIKO SHO (Kobe Steel, Ltd.), National University Corporation Tokai National Higher Education and Research SystemInventors: Akira KISHIMOTO, Katsuya AKIYAMA, Hiroshi MACHIDA, Tsuyoshi YAMAGUCHI, Takehiro ESAKI, Koyo NORINAGA
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Publication number: 20200408743Abstract: An object of the present invention is to provide a novel evaluation system that is particularly useful in researches on the onset mechanism and pathologic conditions of a central nervous system disease, development of a therapeutic method, or the like. The efficacy of a test substance is evaluated using a movement pattern defined by variations in movement of individual cells constituting a cell population as an index.Type: ApplicationFiled: December 21, 2018Publication date: December 31, 2020Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventors: Norio Ozaki, Yuko Arioka, Emiko Higashijima, Daisuke Mori, Itaru Kushima
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Publication number: 20200385419Abstract: A nucleoside that is more practical for RNA pharmaceuticals and other applications and use thereof is represented by formula (1) or (2) below, or a salt thereof: (In formula (1), R1 represents a hydrogen atom, a hydroxyl group, a hydroxyl group in which a hydrogen atom is substituted by an alkyl group or alkenyl group, or a protected group, and in formula (2), X represents a halogen atom. In formula (1) and formula (2), R2 and R3 may be the same or different, and each represents a hydrogen atom etc., R4 represents NHR7 (in which R7 represents a hydrogen atom etc., and B represent represents any of a purine-9-yl group, 2-oxo-pyrimidin-1-yl group, substituted purine-9-yl group or substituted 2-oxo-pyrimidin-1-yl group).Type: ApplicationFiled: October 31, 2018Publication date: December 10, 2020Applicants: YAMASA CORPORATION, National University Corporation Tokai National Higher Education and Research SystemInventors: Yoshihito UENO, Yusuke MAEDA, Ryohei KAJINO