Abstract: Provided are a photon detection device and a photon detection method being practical, capable of performing photon detection in which no afterpulse is generated and generation of a dark count is suppressed, and capable of obtaining a high counting rate with low jitter. The photon detection device of the present invention includes: a photon detection section having a long plate-shaped superconducting stripline whose plate surface is a photon detection surface, and a bias current supply section supplying a bias current to the superconducting stripline; and a single flux quantum comparator circuit capable of detecting magnetic flux scattered from the superconducting stripline upon photon detection.

Abstract: This invention provides an immobilized protein bound to an immobilization carrier at a protein amino terminus via the sole ?-amino group of the protein comprising an amino acid sequence containing neither lysine residues nor cysteine residues represented by the general formula S1-R1-R2, wherein: the sequences are oriented from the amino terminal side to the carboxy terminal side; the sequence of the S1 portion may be absent, but when the sequence of the S1 portion is present, the sequence of the S1 portion is a spacer sequence composed of amino acid residues other than lysine and cysteine residues; the sequence of the R1 portion is the sequence of a subject protein to be immobilized and contains neither lysine residues nor cysteine residues; and the sequence of the R2 portion may be absent, but when the sequence of the R2 portion is present, the sequence of the R2 portion is a spacer sequence composed of amino acid residues other than lysine and cysteine residues.