Abstract: A device for searching a biomarker to be used for determining whether or not a first treatment has an effect on a disease, the biomarker search device includes: a first storage; a second storage storing; a third storage; a fourth storage; a signature molecular information detector; a regression analyzer; a network generator; and a biomarker determinator.

Abstract: Provided are an oxide semiconductor excellent in transparency, mobility, and weatherability, etc., and a semiconductor device having the oxide semiconductor, a p-type semiconductor being realizable in the oxide semiconductor. The oxide semiconductor consists of a composite oxide, which has a crystal structure including a pyrochlore structure, containing at least one or more kinds of elements selected from Nb and Ta, and containing Sn element, and its holes become charge carriers by the condition that Sn4+/(Sn2++Sn4+) which is a ratio of Sn4+ to a total amount of Sn in the composite oxide is 0.124?Sn4+/(Sn2++Sn4+)?0.148.

Abstract: The present invention utilizes an electrochemical catalyst which contains: a metal oxide that is composed of one or more compounds selected from among zirconium oxide, cerium oxide, yttrium oxide, gadolinium oxide, samarium oxide, cobalt oxide and scandium oxide; and a metal variant, which has a valence that is different from the valence of the metal that constitutes the metal oxide.

Abstract: [Problem] To improve the drain current ON/OFF ratio characteristics. [Solution] A tunnel field-effect transistor 10 of the present invention is such that, when the gate length is denoted by LG and the extension distance of a source region 1 extended toward a drain region 3 from a position in the source region 1 is denoted by LOV, LTG expressed in Formula (1) below as the shortest distance between the position of an extension end of the source region 1 based on a drain-side reference position as the side face position of a gate electrode 6a, 6b closest to the drain region 3, and the position in the semiconductor layer 4 opposite to the drain-side reference position in the height direction of the gate electrode 6a, 6b satisfies a condition of Inequality (2) below. Note that lt_OFF in Inequality (2) denotes a shortest tunnel distance over which carriers move from the source region to a channel region through a tunnel junction surface in an OFF state of the tunnel field-effect transistor.

Abstract: This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.

Abstract: A method of manufacturing a magnetoresistive random access memory (MRAM). The method includes forming a first CoFeB layer of the MTJ devices, the first CoFeB layer being amorphous and forming a magnesium oxide (MgO) layer of the MTJ devices over the first CoFeB layer. Further, there is a forming of a second CoFeB layer of the MTJ devices, the second CoFeB layer being amorphous over the MgO layer, and annealing the MTJ devices. The first and second CoFeB layers are crystallized by the annealing, and the MgO layer is poly-crystalline in which a (001) crystal plane is preferentially oriented.

Abstract: A layered structure having high adhesive properties, and high hardness or excellent transparency, is prepared on a base material such as a resin. A layered structure including: an organic-inorganic hybrid member containing a primary inorganic particle and an organic polymer covalently bound to each other, wherein the primary inorganic particle forms a network containing the polymer; and a particle aggregate layer containing a secondary particle which is deposited on the organic-inorganic hybrid member and is composed of an inorganic material or a metallic material; wherein in the organic-inorganic hybrid member, the primary inorganic particle and the secondary particle have different crystal particle sizes.

Abstract: The purpose of the present invention is to provide a mechanoluminescent material which can be exhibit brighter luminescence compared to traditional SAO mechanoluminescent material even with respect to small strains and which has a relatively high mechanoluminescent capability even when left to stand for a long period of time after excitation. Provided is a strontium aluminate mechanoluminescent material containing Zr ions, characterized in that the Zr ions are contained in a reduced state, the content of the Zr ions is 10 mol % or less, and in a thermoluminescence measurement, one or more luminescence peaks are observed at a temperature of 100° C. or higher.

Abstract: An organometallic complex catalyst is disclosed for use in a cross-coupling reaction. In formula (1), M is the coordination center and represents a metal atom such as Pd or an ion thereof. R1, R2, and R3 may be the same or different and are a substituent such as a hydrogen atom. R4, R5, R6, and R7 may be the same or different and are a substituent such as a hydrogen atom. X represents a halogen atom. R8 represents a substituent that has a n bond and 3-20 carbon atoms. With regard to the electron-donating properties of R1-R7 with respect to the coordination center M of the ligand containing R1-R7 that is indicated in formula (2), R1-R7 are arranged in combination such that the TEP value obtained from infrared spectroscopy shifts toward the high frequency side compared to the TEP value of the ligand of formula (2-1).

Abstract: The present invention provides a plasma torch which comprises: a first pipe having a first flow channel through which a liquid can flow, a first exit through which the liquid is sprayed being provided on an one end side; a second pipe body that surrounds the first pipe body, and has a second flow channel through which a gas can flow, a second exit through which the gas is sprayed being provided on the one end side; and an electrode extending into the second flow channel. The second exit is provided further to the one end side than the first exit, some of the inner peripheral surface of the second pipe decreases in diameter towards the second exit, and the diameter of the inner peripheral surface closer to the second exit than the first exit is equal to or larger than the opening diameter of the first exit.

Abstract: An information processing apparatus includes: a corresponding data calculation unit configured to determine importance of each sample in accordance with a difference between a plurality of pieces of observation information observed when an input is given to an observation target and data of a second type generated by a simulator that simulates the observation target based on a sample of a parameter with respect to a plurality of samples and data of a first type indicating the input, and a degree of influence of the sample on distribution of parameters, and then calculate data that corresponds to the distribution of the parameters; a new parameter sample generation unit configured to generate a new sample of the parameters in accordance with predetermined processing using the data that corresponds to the distribution of the parameters; and an iteration control unit configured to perform control so as to repeat the above processing.

Abstract: To detect a target substance accurately and effectively, a target substance detection device 1 includes: a liquid-sample introducing plate 2 formed from a light-transmissive plate having a surface on which a liquid sample including a target substance and magnetic particles forming a conjugate with the target substance is introduced, and enabling propagating transmitted light of light irradiated from the rear face upward of the surface as propagated light; a rear face light irradiation unit 3 configured to be able to irradiate the liquid-sample introducing plate 2 with light from the rear face; a first magnetic field application unit 4 disposed on the side of the surface of the liquid-sample introducing plate 2, and configured to apply a magnetic field to move the conjugate in the liquid sample that is introduced on the surface of the liquid-sample introducing plate in the direction away from the liquid-sample introducing plate 2; and an optical-signal detection unit 5 disposed on the side of the surface of th

Abstract: An authentication system is provided with: a first input unit and a second input unit into which authentication information can be input; a first computing unit which performs computation on the basis of the authentication information input into the first input unit and a communication counterpart-side authentication parameter registered in a communication counterpart; a second computing unit which performs computation on the basis of the authentication information input into the second input unit and a portable terminal-side authentication parameter registered in a portable terminal; and authentication units which, if the authentication information has been input into the first or the second input unit, perform authentication on the basis of the result of computation by corresponding computing unit and the portable terminal-side authentication parameter.

Abstract: The present invention provides a microwave processing apparatus, including: a cavity resonator having a cavity that forms a standing wave of a microwave; and a dielectric portion disposed occupying at least one-fifth of a volume of the cavity, in the cavity, in which an object to be processed being at through at least one end side of the cavity resonator is disposed in the cavity resonator, and the object to be processed is processed by the standing wave.

Abstract: An analysis device applies, for each of a plurality of candidates set according to a update target parameter value, the update target parameter value and the candidate to a machine learning result to acquire information, the information indicating a degree of difference of an evaluation target value in a case of the candidate with respect to an evaluation target value in a case of the update target parameter value; calculates, for each candidate, an evaluation target value in a case of the candidate, based on the degree of difference of the evaluation target values and the evaluation target value in the case of the update target parameter value; and compares the evaluation target values in a case of each of the plurality of candidates and selects a candidate from the plurality of candidates based on a result of the comparison.

Abstract: Parameters are efficiently calculated. An information processing apparatus (1) includes a corresponding data calculation unit (2) configured to determine importance of each sample in accordance with a difference between a plurality of pieces of observation information observed when an input is given to an observation target and data of a second type generated by a simulator that simulates the observation target based on a sample of a parameter with respect to the plurality of samples and data of a first type indicating the input, and a contribution degree of each of the pieces of observation information in the plurality of pieces of observation information, and calculate data that corresponds to distribution of the parameters; and a new parameter sample generation unit (3) configured to generate a new sample of the parameters in accordance with predetermined processing using data that corresponds to distribution of the parameters.

Abstract: In the present invention, a composition comprising two types of thienothiophene compounds selected from the group consisting of the compounds indicated by formulas (1) to (4) (in formulas (1) to (4), either one of R1 and R2 represents an alkyl group, an aromatic hydrocarbon group having an alkyl group or a heterocyclic group having an alkyl group, and the other represents a hydrogen atom, an aromatic hydrocarbon group, a heterocyclic group or a substituent represented by formula (5) (in formula (5), R3 represents an aromatic hydrocarbon group or a heterocyclic group)) can form an organic thin film which is homogeneous over a large area, and an organic semiconductor device including the organic thin film is capable of exhibiting high mobility.

Abstract: An analysis device applies, for each of a plurality of candidates for an updated parameter value set according to an update target parameter value, the update target parameter value and the candidate to a plurality of machine learning results to acquire, for each machine learning result, information indicating a degree of difference of an evaluation target value in a case of the candidate with respect to an evaluation target value in a case of the update target parameter value; calculate, for each candidate and for each machine learning result, an evaluation target value in the case of the candidate based on the degree of difference and the evaluation target value in the case of the update target parameter value; and calculate a selection index value for each candidate using a variation in the evaluation target values for each machine learning result, compare the selection index value of each candidate.

Abstract: A modified pigment having excellent color tone selectivity is provided by laking dye by an environmentally friendly method without using metal. A modified pigment according to the present invention is obtained by laking a dye containing at least one of an acidic group and a basic group with at least one of an amino acid and protein.

Abstract: Provided is a method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system, the method including the step of culturing neural crest cells in the presence of at least one of a BMP signaling pathway activator, an SHH signaling pathway inhibitor, and a Wnt signaling pathway inhibitor.