Abstract: Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
Type:
Grant
Filed:
October 4, 2013
Date of Patent:
May 8, 2018
Assignees:
Northeastern University, National Institute of Agricultural Technology, University of Padova
Inventors:
Juan Sebastian Pappalardo, Micaela Toniutti, Stefano Salmaso, Tatyana S. Levchenko, Vladimir Torchilin