Patents Assigned to National Institutes for Quantum and Radiological Science and Technology
  • Patent number: 10500414
    Abstract: Provided is an irradiation planning apparatus including: a three-dimensional CT value data acquisition unit (36); a prescription data input processing unit (32) which acquires prescription data; a stopping power ratio conversion unit (37) and a nuclear reaction effective density conversion unit (38) which respectively generate first conversion data (41) and second conversion data (42) on the basis of three-dimensional CT value data; and a calculation unit (33) which calculates a dose distribution on the basis of the prescription data, the first conversion data (41), and the second conversion data (42), wherein the stopping power ratio conversion unit (37) and the nuclear reaction effective density conversion unit (38) perform correction processing for correcting data obtained from the three-dimensional CT value data, using a physical quantity indicative of a likelihood of spalling particles of incident charged particle beam (3), and then determine the dose distribution.
    Type: Grant
    Filed: October 24, 2015
    Date of Patent: December 10, 2019
    Assignee: National Institutes for Quantum and Radiological Science and Technology
    Inventors: Taku Inaniwa, Nobuyuki Kanematsu
  • Patent number: 10444383
    Abstract: A partial-ring PET device, in which some of coincidence radiation detectors to be arranged in a ring shape around a field of view for detecting lines of response of annihilation radiations are missing, is compensated for a drop in image quality due to the missing of the coincidence radiation detectors by including single gamma-ray radiation detectors for detecting at least either one of the annihilation radiations as a single gamma-ray. This can reduce missing of projection angles and reduce artifacts in PET images.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 15, 2019
    Assignee: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Taiga Yamaya, Hideaki Tashima
  • Publication number: 20190302206
    Abstract: PET or SPECT insert for MRI or MRS system with medium (3 T for example) to ultra high (7 T for example) magnetic field is provided. RF shielded radiation detector modules are separately disposed in a form of full or partial ring shape. The RF shielded radiation detector modules are electric ground conductors for microstrip transmission line coil RF array. Decoupling circuits in between grounded shield and/or in between microstrip conductors make electric isolation between coil elements.
    Type: Application
    Filed: March 28, 2019
    Publication date: October 3, 2019
    Applicant: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Md Shahadat Hossain Akram, Takayuki OBATA, Taiga YAMAYA
  • Patent number: 10420202
    Abstract: According to some embodiments, an accelerator control device has a high-frequency power controller and a timing controller. The high-frequency power controller supplies high frequency power for accelerating a charged particle beam to an accelerator. The timing controller controls an operation timing of a blocker that blocks the charged particle beam emitted from the accelerator based on a current value of the charged particle beam circulating in the accelerator.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: September 17, 2019
    Assignees: Toshiba Energy Systems & Solutions Corporation, National Institutes for Quantum and Radiological Science and Technology
    Inventors: Munemichi Matsumoto, Takuji Furukawa, Kota Mizushima, Katsushi Hanawa
  • Patent number: 10315052
    Abstract: Provided is a prediction device for skin change from radiation exposure, the device being capable of precisely predicting a skin reaction to radiation exposure. Also provided are a verification device, a program for the prediction device for skin change, and a program for the verification device. A prediction device (4) for skin change from radiation exposure includes: a radiation information accepting unit (11) that accepts input of radiation information regarding expected exposure to radiation; a pre-exposure skin image acquiring unit (21) that acquires a skin image that captures skin of a living body; a change computing unit that computes the change of the skin due to exposure to the radiation determined by the radiation information and that obtains from the skin image a post-change prediction skin image; and a prediction skin image outputting unit (25) that outputs the prediction skin image.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: June 11, 2019
    Assignee: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Hiroaki Matubara, Naruhiro Matufuji
  • Patent number: 10294419
    Abstract: [Problem] To provide highly heat-resistant and radiation-resistant radiation measuring equipment. [Solution] Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: May 21, 2019
    Assignees: Denka Company Limited, National University Corporation Gunma University, National Institutes For Quantum And Radiological Science And Technology
    Inventors: Wataru Kada, Kenta Miura, Osamu Hanaizumi, Tomihiro Kamiya, Takahiro Satoh, Junichi Susaki, Suzuya Yamada
  • Patent number: 10271782
    Abstract: A suction drain device of a disclosed liquid collecting apparatus actively pushes and pulls blood. This achieves liquid collection at high speed even under decreased pressure depending on a physiological state of an animal. Moreover, the liquid collecting apparatus includes a first flow path and a second flow path having a given length. Accordingly, the flow path with a given length set in advance and thus a known volume allows collection of a given amount volume of blood without measuring a length and an amount of blood using a volume measuring device. Accordingly, no need of the measuring device allows reduction in size of the liquid collecting apparatus. Consequently, the liquid collecting apparatus can be installed adjacent to the animal to achieve reduction in dead volume. Moreover, blood is flown to a fourth flow path branched with a connecting terminal, and is also flown to the second flow path branched with a connecting terminal.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: April 30, 2019
    Assignees: SHIMADZU CORPORATION, NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY, NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY
    Inventors: Nobuya Hashizume, Keishi Kitamura, Takahiro Nishimoto, Yuichi Kimura, Hiroshi Toyama, Takashi Yamada
  • Patent number: 10234570
    Abstract: In a PET device, a first detector includes a plurality of first scintillators and detects gamma rays emitted from positron-emitting radionuclides injected into a subject. A second detector is provided on the outer circumferential side of the first detector, includes a plurality of second scintillators arranged in an arrangement surface density lower than that of the first scintillators, and detects gamma rays that have passed through the first detector. A counted information acquiring unit acquires, as first counted information and second counted information, the detection positions, energy values, and detection time regarding gamma rays detected by the first detector and the second detector. Based on the detection time contained in each of the first counted information and the second counted information, an energy value adder generate corrected counted information by summing the energy values contained in the first counted information and the second counted information.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: March 19, 2019
    Assignees: Toshiba Medical Systems Corporation, National Institutes for Quantum and Radiological Science and Technology
    Inventors: Taiga Yamaya, Takayuki Obata, Iwao Kanno, Takuzo Takayama, Hitoshi Yamagata, Kazuya Okamoto
  • Publication number: 20190032230
    Abstract: The disclosure relates to recovering Li ions in a raw liquid into a recovery liquid at a high recovery speed. A lithium selective permeable membrane is constituted of a selective permeable membrane main body constituted of a lithium ion superconductor (ion conductor) having a particularly high ion conductivity and a Li adsorption layer formed as a thin layer on a raw liquid side (a first electrode) thereof. As a material constituting the selective permeable membrane main body, specifically, lanthanum lithium titanium oxide can be used. The Li adsorption layer is formed as a thin layer on a surface of the selective permeable membrane main body by carrying out a chemical treatment on the selective permeable membrane main body.
    Type: Application
    Filed: January 26, 2017
    Publication date: January 31, 2019
    Applicant: National Institutes for Quantum and Radiological Science and Technology
    Inventor: Tsuyoshi HOSHINO
  • Patent number: 10143431
    Abstract: A medical image processing apparatus, includes: a reconstructed moving image obtainer that obtains a reconstructed moving image; a focus region identifier that identifies a first focus region corresponding to the designated focus; a fluoroscopic moving image obtainer that obtains at least one-period data on a fluoroscopic moving image; a second characteristics identifier that identifies each of two or more second characteristics regions corresponding to the internal body portion; a comparison selector that compares the two or more first characteristic regions; a conversion parameter calculation unit that calculates a conversion parameter for converting the first characteristic region.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: December 4, 2018
    Assignees: TOSHIBA ENERGY SYSTEMS & SOLUTIONS CORPORATION, NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Ryusuke Hirai, Yukinobu Sakata, Yasunori Taguchi, Fumi Maruyama, Shinichiro Mori
  • Publication number: 20180317311
    Abstract: According to some embodiments, an accelerator control device has a high-frequency power controller and a timing controller. The high-frequency power controller supplies high frequency power for accelerating a charged particle beam to an accelerator. The tinting controller controls an operation timing of a blocker that blocks the charged particle beam emitted from the accelerator based on a current value of the charged particle beam circulating in the accelerator.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 1, 2018
    Applicants: Toshiba Energy Systems & Solutions Corporation, National Institutes for Quantum and Radiological Science and Technology
    Inventors: Munemichi MATSUMOTO, Takuji Furukawa, Kota Mizushima, Katsushi Hanawa
  • Patent number: 10090132
    Abstract: A charged particle beam irradiation apparatus according to an embodiment includes: a first scanning electromagnet device configured to deflect a charged particle beam to a second direction that is substantially perpendicular to a first direction along which the charged particle beam enters, the first scanning electromagnet device having an aperture on an outlet side larger than that on an inlet side; and a second scanning electromagnet device configured to deflect the charged particle beam to a third direction that is substantially perpendicular to the first direction and the second direction, the second scanning electromagnet device having an aperture on an outlet side larger than that on an inlet side, the first scanning electromagnet device and the second scanning electromagnet device being disposed to be parallel with the first direction.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: October 2, 2018
    Assignees: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY, TOSHIBA ENERGY SYSTEMS & SOLUTIONS CORPORATION
    Inventors: Takuji Furukawa, Shigeki Takayama, Takashi Yazawa, Yoshiharu Kanai, Kosuke Sato, Tomofumi Orikasa, Kei Koyanagi
  • Publication number: 20180239037
    Abstract: A partial-ring PET device, in which some of coincidence radiation detectors to be arranged in a ring shape around a field of view for detecting lines of response of annihilation radiations are missing, is compensated for a drop in image quality due to the missing of the coincidence radiation detectors by including single gamma-ray radiation detectors for detecting at least either one of the annihilation radiations as a single gamma-ray. This can reduce missing of projection angles and reduce artifacts in PET images.
    Type: Application
    Filed: February 13, 2018
    Publication date: August 23, 2018
    Applicant: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Taiga YAMAYA, Hideaki TASHIMA
  • Patent number: 10031128
    Abstract: A screening method evaluates influence of a cytotoxic factor on lymphoid cells. The method includes administering or irradiating lymphoid cells with the cytotoxic factor that injures the lymphoid cells; incubating the lymphoid cells to which the cytotoxic factor is administered or irradiated for a selected time; measuring a cell size of the lymphoid cells after the incubation; and determining influence of the cytotoxic factor on the lymphoid cells based on a change of the cell size. According to this method, influence of radiation or a drug, or efficacy of radiation, a radiation-protecting agent, an antioxidant, a radiation-sensitizing agent, a drug, or ultraviolet rays can be evaluated economically and objectively in a short period of time.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: July 24, 2018
    Assignee: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Emiko Sekine, Takashi Shimokawa, Megumi Ueno, Etsuko Nakamura, Miyako Nakawatari, Takeshi Murakami, Takashi Imai, Kazunori Anzai, Kenichiro Matsumoto, Ikuo Nakanishi
  • Patent number: 9933529
    Abstract: A layered three-dimensional radiation position detector includes two-dimensional scintillator arrays that are pixelated by optically discontinuous surfaces and stacked on a light receiving surface of a light receiving element, responses of scintillator elements detecting radiations being made identifiable on the light receiving surface to obtain a three-dimensional radiation detection position. A scintillator array lying on a radiation incident surface side has a pixel pitch smaller than that of a scintillator array lying on a light receiving element side so that the scintillator array on the radiation incident surface side has increased resolution. A layered three-dimensional radiation position detector achieving both low cost and high resolution can thus be provided.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: April 3, 2018
    Assignee: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Eiji Yoshida, Taiga Yamaya
  • Patent number: 9932653
    Abstract: Problem is to selectively and inexpensively recover a metal ion in a liquid. Solution is a metal ion recovery device, in which a permselective membrane for selectively permeating Li is used, and on both main faces of the plate-like permselective membrane, a mesh-like negative electrode and a positive electrode are formed, respectively. This structure is provided in a treatment tank, and in the treatment tank, the permselective membrane partitions between a stock solution containing a Li ion, and a recovery solution into which Li is recovered. As the permselective membrane, lithium nitride (Li3N), Li10GeP2S12, (Lax, Liy)TiOz, Li1+x+yAlx(Ti, Ge)2?xSiyP3?yO12, and the like, which are super lithium ion conductors, can be used.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: April 3, 2018
    Assignee: National Institutes for Quantum and Radiological Science and Technology
    Inventor: Tsuyoshi Hoshino
  • Patent number: 9892526
    Abstract: A radiotherapy apparatus includes an receiver receiving a first projection image of a calibration object under X-ray imaging; a storing portion storing an ideal projection image of the calibration object, the ideal projection image generated based on design information of an X-ray imaging structure, positional information of the calibration object, and volume data of the calibration object; a calculator calculating a transformation parameter for transforming the first projection image into an ideal projection image; a transformed image generator generating a transformed projection image of the patient by transforming a second projection image of a patient obtained under X-ray imaging with the transformation parameter; a reconstructed image generator generating a reconstructed projection image based on volume data of the patient, positional information of the patient, and the design information; and a matching image generator generating a matching reference image used for matching between the transformed proje
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: February 13, 2018
    Assignees: KABUSHIKI KAISHA TOSHIBA, National Institutes for Quantum and Radiological Science and Technology
    Inventors: Ryusuke Hirai, Yukinobu Sakata, Yasunori Taguchi, Tomoyuki Takeguchi, Shinichiro Mori, Fumi Maruyama
  • Patent number: 9880236
    Abstract: In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a magnet that is a seamless structure generates a static magnetic field in a bore having a cylindrical shape. First detectors and second detectors are each formed in a ring shape and detect gamma rays emitted from positron emitting radionuclides injected into a subject. The first detectors and the second detectors are disposed with a space therebetween in an axial direction of the bore so as to interpose the magnetic field center of the static magnetic field therebetween.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: January 30, 2018
    Assignees: National Institute for Quantum and Radiological Science and Technology, Toshiba Medical Systems Corporation
    Inventors: Takayuki Obata, Taiga Yamaya, Iwao Kanno, Hitoshi Yamagata, Takuzo Takayama, Kazuya Okamoto
  • Patent number: 9864028
    Abstract: In a PET (Positron Emission Tomography)-MRI (Magnetic Resonance Imaging) apparatus of an embodiment, a transmitting radio frequency coil applies a radio frequency magnetic field on a subject placed in a static magnetic field. A detector is formed in a ring shape, disposed on a side adjacent to an outer circumference of the transmitting radio frequency coil, includes at least two PET detectors disposed with a space therebetween in an axial direction of a bore so as to interpose the magnetic field center of the static magnetic field therebetween, and detects gamma rays emitted from positron emitting radionuclides injected into the subject. Radio frequency shields are each formed in an approximately cylindrical shape, disposed between the transmitting radio frequency coil and the detector, and shield the radio frequency magnetic field generated by the transmitting radio frequency coil.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: January 9, 2018
    Assignees: National Institutes for Quantum and Radiological Science and Technology, Toshiba Medical Systems Corporation
    Inventors: Iwao Kanno, Takayuki Obata, Taiga Yamaya, Kazuya Okamoto, Takuzo Takayama, Hitoshi Yamagata
  • Publication number: 20170304650
    Abstract: Provided is an irradiation planning apparatus including: a three-dimensional CT value data acquisition unit (36); a prescription data input processing unit (32) which acquires prescription data; a stopping power ratio conversion unit (37) and a nuclear reaction effective density conversion unit (38) which respectively generate first conversion data (41) and second conversion data (42) on the basis of three-dimensional CT value data; and a calculation unit (33) which calculates a dose distribution on the basis of the prescription data, the first conversion data (41), and the second conversion data (42), wherein the stopping power ratio conversion unit (37) and the nuclear reaction effective density conversion unit (38) perform correction processing for correcting data obtained from the three-dimensional CT value data, using a physical quantity indicative of a likelihood of spalling particles of incident charged particle beam (3), and then determine the dose distribution.
    Type: Application
    Filed: October 24, 2015
    Publication date: October 26, 2017
    Applicant: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY
    Inventors: Taku INANIWA, Nobuyuki KANEMATSU