Patents Assigned to National Pingtung University of Science & Technology
  • Patent number: 11856971
    Abstract: The invention discloses a method for improving immunity in shrimps, by administering an extract of cocoa rind to a shrimp body to improve immunity of the shrimp body. The extract of cocoa rind is obtained by extracting a dried sample of cocoa rind by an aqueous ethanol solution with a concentration of ethanol being 90-98%. The dried sample of cocoa rind has a water content of 2-5%.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: January 2, 2024
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventors: Wen-Teng Cheng, Wan-Lin Tsai, Hsin-Wei Kuo, Yu-Fen Liu, Chin-Chyuan Chang, Yu-Hung Lin
  • Patent number: 11834647
    Abstract: The present invention relates to an in vitro immune synapse system and a method of in vitro evaluating immune response using the same. The in vitro immune synapse system includes antigen-presenting cells (APCs) and at least one cell type of several specific T cell subtypes isolated from peripheral blood mononuclear cells (PBMCs), all of which is from a same individual of pigs. When a test sample is co-cultured in the in vitro immune synapse system for a given period, it can be determined that the test sample is immunogenic, immunostimulatory or not according to the immunization-related changes of these cells, thereby potentially replacing some kinds of animal experimentation.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: December 5, 2023
    Assignee: National Pingtung University of Science and Technology
    Inventors: Hso-Chi Chaung, Wen-Bin Chung, Ann Ying-An Chen, Mei-Li Wu
  • Patent number: 11759868
    Abstract: A holder provided for mounting of a lathe cutter includes a carrier, a first joint seat, a second joint seat, a limit rod and a clamp member. The first and second joint seats are disposed on a first and second base of the carrier respectively. The lathe cutter is mounted between the first and second joint seats. The limit rod is inserted into a through hole of the lathe cutter, and a first and second ends of the limit rod are coupled to the first and second joint seats respectively. The clamp member is disposed on the limit rod. The clamp member and the second joint seat are provided to clamp the lathe cutter to separate the lathe cutter from the first and second bases.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: September 19, 2023
    Assignee: National Pingtung University of Science and Technology
    Inventors: Wei-Tai Huang, Xi-Sang Chen, Zhi-Yao Tu
  • Patent number: 11682650
    Abstract: A heat assisted flip chip bonding apparatus includes a semiconductor assembly having a substrate and a chip, a heating source and a press and cover assembly having a cover element and press elements. The chip is disposed above the substrate and includes conductors which contact with conductive pads on the substrate. The heating source is provided to emit a heated light which illuminates the chip via an opening of the cover element. The press elements are located between the cover element and the semiconductor assembly and each includes an elastic unit and a pressing unit. Both ends of the elastic unit are connected to the cover element and the pressing unit respectively, and the pressing unit is provided to press a back surface of the chip.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: June 20, 2023
    Assignee: National Pingtung University of Science and Technology
    Inventor: Wei-Hua Lu
  • Patent number: 11660708
    Abstract: A TIG welding flux for dissimilar steels is used to solve the problem that the conventional friction stir welding procedure for butt-joint welding a stainless steel workpiece and a carbon steel workpiece cannot be used on site, as well as the problem that the increased operating time and manufacturing cost due to forming bevel faces on both the stainless steel workpiece and the carbon steel workpiece. The TIG welding flux for dissimilar steels includes 25-35 wt % of silicon dioxide (SiO2), 20-30 wt % of cobalt (II, III) oxide (Co3O4), 15-20 wt % of manganese (II, III) oxide (Mn3O4), 10-15 wt % of nickel (III) oxide (Ni2O3), 7-12 wt % of molybdenum trioxide (MoO3), 6-11 wt % of manganese (II) carbonate (MnCO3), 5-10 wt % of nickel (II) carbonate (NiCO3), and 2-4 wt % of aluminum fluoride (AlF3).
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: May 30, 2023
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Kuang-Hung Tseng
  • Patent number: 10820595
    Abstract: Provided herein is Bacillus amyloliquefaciens strain PMB05 used in the field of plant disease control. Inoculation of plants with the strain can increase immune responses induced by detection of fungi and/or bacteria in plant, for example, increase the production of ROS and deposition of callose. Also, the strain has the effect of promoting plant growth. Therefore, the strain and its culture filtrate of the present invention can boost plant disease resistance and promote plant growth, which can be extensively used to control plant diseases and have the potential of turning into a commodified biological control agent.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: November 3, 2020
    Assignee: National Pingtung University of Science and Technology
    Inventors: Yi-Hsien Lin, Ting-Hsin Ho
  • Patent number: 10793474
    Abstract: A ceramic composition which can be used as a sintering aid includes 1-2 mol % of magnesium oxide (MgO), 5-15 mol % of aluminum oxide (Al2O3), 25-40 mol % of silicon dioxide (SiO2), 40-55 mol % of calcium oxide (CaO), 0.1-8 mol % of ferric oxide (Fe2O3), 0.1-2 mol % of sulfur trioxide (SO3) and 0.1-2 mol % of titanium oxide (TiO2). Alternatively, the ceramic composition includes 1-8 mol % of MgO, 5-15 mol % of Al2O3, 25-40 mol % of SiO2, 40-55 mol % of CaO, 0.1-8 mol % of Fe2O3, 0.1-2 mol % of SO3 and 0.9-2 mol % of TiO2.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: October 6, 2020
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Ying-Chieh Lee
  • Patent number: 10792769
    Abstract: A welding flux for duplex stainless steel is used to solve the problem of insufficient penetration depth of a weld formed between two jointed workpieces when workpieces with a thickness above 3 mm is joined by TIG welding. The welding flux for duplex stainless steel includes 25-35 wt % of SiO2, 20-25 wt % of Cr2O3, 10-20 wt % of MoO3, 10-15 wt % of NiO, 5-10 wt % of FeO, 5-10 wt % of Co3O4, 5-10 wt % of MnO2 and 3-5 wt % of CuO.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: October 6, 2020
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Kuang-Hung Tseng
  • Patent number: 10689421
    Abstract: The present invention relates to a bacteriocin-producing Paenibocillus ehimensis strain NPUST-1, which can intensify the growth and immune response of aquaculture organisms. Also, the strain can increase the survival rate of aquaculture organisms after pathogen infection. A bacteriocin produced by the Paenibocillus ehimensis strain NPUST-1, Peocin, is a starvation/stationary phase protection protein, which has antimicrobial activity against various pathogen including aquaculture pathogens, foodborne pathogens and clinical pathogens. The bacteriocin Peocin is a starvation/stationary phase protection protein having antimicrobial activity found for the first time.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: June 23, 2020
    Assignee: National Pingtung University of Science and Technology
    Inventor: Shao-Yang Hu
  • Patent number: 10619149
    Abstract: A fusant F001 able to digest polysaccharides is formed by protoplast fusion between Bacillus amyloliquefaciens and Bacillus coagulans. The fusant F001 is deposited at NITE Patent Microorganisms Depositary (NPMD) in Japan with a deposit number NITE BP-02873.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: April 14, 2020
    Assignees: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY, BIOMIXIN CO., LTD.
    Inventors: Yo-Chia Chen, Rung-Sheng Peng
  • Patent number: 10494396
    Abstract: The present invention relates to a method of separating betanin from red quinoa by supercritical fluid fractionation, including: mixing an extract of red quinoa with an ethanol/water mixture to obtain a mixture of red quinoa/ethanol/water; and separating betanin from the mixture of red quinoa/ethanol/water by supercritical fluid fractionation, which operates under a pressure between 2300 to 4400 psi at a temperature between 35 to 65° C. for a period of time between 15 to 90 minutes.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: December 3, 2019
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Ho-Hsien Chen, Chen-Hsing Yu, Nyvonne Tiqu Gina Nelma
  • Patent number: 10470596
    Abstract: A hook assembly includes a base having a chamber, a hook portion provided on a bottom of the base, and a lean indicator mounted in the base via a second pivotal portion. The base includes an opening, a window portion, and an adhesion portion which is adhered to a surface. The adhesion portion and the opening are provided on a back plate. The base includes two first pivotal portions. A center of each first pivotal portion is spaced from the surface at a spacing. The lean indicator includes first and second faces. The first face has a feature different from that of the second face. A central axis of the second pivotal portion does not pass through a center of gravity of the lean indicator. The central axis of the second pivotal portion is spaced from each edge of the lean indicator at a distance slightly larger than the spacing.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: November 12, 2019
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Chien-Ho Ko
  • Patent number: 10434594
    Abstract: The invention provides an ignition flux for arc stud welding, including 30-55 wt % SiO2, 30-55 wt % NiO, 10-35 wt % AlF3, and 5-25 wt % NiF2, or including 30-55 wt % TiO2, 30-55 wt % NiO, 10-35 wt % AlF3, and 5-25 wt % NiF2. As such, the electric arc can be easily created and smoothly formed. The invention further provides an arc stud welding method utilizing such ignition flux. As such, the fastener and the metal workpiece can be tightly connected together without the need of inserting an ignition tip into the welding portion of a fastener.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: October 8, 2019
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Kuang-Hung Tseng
  • Publication number: 20190241620
    Abstract: The present invention relates to a bacteriocin-producing Paenibocillus ehimensis strain NPUST-1, which can intensify the growth and immune response of aquaculture organisms. Also, the strain can increase the survival rate of aquaculture organisms after pathogen infection. A bacteriocin produced by the Paenibocillus ehimensis strain NPUST-1, Peocin, is a starvation/stationary phase protection protein, which has antimicrobial activity against various pathogen including aquaculture pathogens, foodborne pathogens and clinical pathogens. The bacteriocin Peocin is a starvation/stationary phase protection protein having antimicrobial activity found for the first time.
    Type: Application
    Filed: March 27, 2018
    Publication date: August 8, 2019
    Applicant: National Pingtung University of Science and Technology
    Inventor: Shao-Yang HU
  • Publication number: 20190110407
    Abstract: An inflatable planting device including a storage tank, a cultivation tank, a field planting tray and a plurality of planting frames is provided. The storage tank has a first air bag. The cultivation tank has a second air bag, and is located on the storage tank. The field planting tray has a mesh air bag defining a plurality of plant holes, and the field planting tray is located on the cultivation tank. The planting frames have a third air bag, and are connected to a periphery of the storage tank, the cultivation tank and the field planting tray through a plurality of connecting holes, where the connecting holes connect the first air bag, the second air bag, the mesh air bag and the third air bag to make the storage tank, the cultivation tank, the field planting tray and the planting frames to form an integrated connection.
    Type: Application
    Filed: November 24, 2017
    Publication date: April 18, 2019
    Applicants: Chunghwa Picture Tubes, LTD., National Pingtung University of Science and Technology
    Inventors: Shih-Wei Su, Ru-Yi Hsieh, Tsung-Meng Wu
  • Publication number: 20190055517
    Abstract: This invention provides a cell line of M2C macrophage and its applications. The cell line is derived from monocytes isolated from bone marrows and peripheral blood. The monocytes were differentiated into M2 macrophage by macrophage colony-stimulating factor (M-CSF), and then the polarization of M2C macrophage was induced by baicalin. The MERTK, PTX3, and PD-L1 expression level of the M2C macrophage are high and promote phagocytosis. Hence it can be applied to cell therapy or biological agents of immune regulation. Also, the macrophage-conditioned medium and wound dressing prepared on the M2C cell have the effects of enhancing fibroblast proliferation and angiogenesis, which can improve wound healing in medical use, and can be applied to skin care product for skin repair and rejuvenation.
    Type: Application
    Filed: December 22, 2017
    Publication date: February 21, 2019
    Applicant: National Pingtung University of Science and Technology
    Inventor: Ko-Tung CHANG
  • Patent number: 10131918
    Abstract: An isolated nucleic acid includes a sequence selected from the group consisting of the following: (i) a first nucleotide sequence of SEQ ID NO.: 7, SEQ ID NO.: 3, SEQ ID NO.: 9, or SEQ ID NO.: 5; (ii) a second nucleotide sequence encoding the amino acid sequence of SEQ ID NO.: 6, SEQ ID NO.: 4, SEQ ID NO.: 8, or SEQ ID NO.: 10; and (iii) a third nucleotide sequence complementary to the first nucleotide sequence or the second nucleotide sequence.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: November 20, 2018
    Assignee: National Pingtung University of Science and Technology
    Inventors: Fure-Chyi Chen, Jian-Zhi Huang, Chen-Yu Lee, Ting-Chi Cheng, Shih-Wen Chin
  • Patent number: 10121575
    Abstract: A thin film resistor includes 38-60 at.% of nickel, 10-25 at.% of chromium, 3-10 at.% of manganese, 4-18 at.% of yttrium, and 1-36 at.% of dysprosium. The thin film resistor can greatly increase the resistivity with a low temperature coefficient of resistance to broaden the applications of the thin film resistor.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: November 6, 2018
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventor: Ying-Chieh Lee
  • Patent number: 10117929
    Abstract: The present invention relates to a nucleic acid-based adjuvant and a porcine vaccine composition including the same. The nucleic acid-based adjuvant, which is a nucleic acid fragment consisting of a sequence listing as SEQ ID NO: 1, can be used as the nucleic acid-based adjuvant of a vaccine composition, thereby elevating the protective ability of the porcine vaccine composition.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: November 6, 2018
    Assignee: National Pingtung University of Science and Technology
    Inventors: Hso-Chi Chaung, Guan-Ming Ke, Mei-Li Wu
  • Patent number: 10070870
    Abstract: A medical drill bit comprises an accommodating slot disposed concavely on a main body of the medical drill bit, a separate board disposed in the accommodating slot to separate the accommodating slot into a first slot and a second slot, and a lid engaging with the separate board and covering the accommodating slot. The lid and the separate board do not rotate with the main body when the main body in rotation. The accommodating uses to fill with cooling liquid which able to be pumped out from the accommodating slot, and fresh cooling liquid is able to inject into the accommodating slot for cooling the drill bit in rotation.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: September 11, 2018
    Assignee: NATIONAL PINGTUNG UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventors: Wei-Hua Lu, Yung-Chuan Chen