Abstract: The present invention provides an antimicrobial composition for topical application, preferably for treating acne, and a method for using the composition. The composition comprises a photocatalyst mixture comprising a photocatalyst, such as titanium dioxide, and sodium perborate, magnesium silicate, and citric acid. The photocatalyst mixture is in an amount effective as an antimicrobial under visible light. The method comprises applying the composition to a target area of the skin and exposing the area to visible light.

Abstract: Compounds of the formula (I) wherein R1 represents a hydrogen atom or a 3-halogen atom, and R2 represents a straight-chain alkyl group containing up to 6 carbon atoms, a straight-chain alkyl group containing up to 3 carbon atoms with unsubstituted or substituted aromatic ring, or alkoxycarbonyl substituent at the end position, or aryloxyalkoxyalkyl group have been found to possess antimalarial activity against Plasmodium falciparum lines, including those resistant against pyrimethamine and other antifolates. The compounds themselves, methods of making these compounds, and methods of using these compounds are all disclosed.

Abstract: Optical touch switches are implemented based on the use of light total internal reflection and light scattering concepts. The optical touch switch basically consists of a light source, a light guide, a photodetector, and an electronic controller. The fingertip touching on the touching surface of the optical touch switch leads to the change in electrical current produced by the photodetector. As a result, the electronic control box senses this change of electrical current and allows the electrical load to stay at the desired state. Key advantages include ease of implementation, prevention of the light beam incident directly on the user's eyes, and ability to accept both strong and weak mechanical forces from users.

Abstract: The developed reagent is three-color immunophenotyping reagent for measurement of CD4 positive lymphocytes in peripheral blood. The reagent contains 7-aminoactinomycin D (7-AAD) which intercalates into double stranded DNA and is easily excited at 488 nm. The fluorescence emission of 7-AAD has peak at 670 nm that can be detected with FL3 detector of flow cytometer. The 7-AAD, therefore, stains white blood cells and discriminates it from red blood cells. The reagent also contains fluorescein isothiocyanate (FITC) labeled CD4 monoclonal antibody and phycoerythrin (PE) labeled CD14 monoclonal antibody which are detected with FL1 and FL2 detectors of flow cytometer, respectively. The developed reagent can be used to measure number of CD4 positive lymphocytes in lymphocyte population and monitor monocyte contamination simultaneously. This reagent therefore provides more accuracy results of CD4 positive lymphocyte enumeration.

Abstract: 1′-Acetoxychavicol acetate is a compound not known before to possess anti-tuberculous activity. The above data revealed that the compound was active against the standard H37Ra strain as well as several clinical isolates at the concentration well below the toxic concentration against various mammalian cells. The compound is therefore potentially useful as an therapeutic and preventive agent for tuberculosis as well as an antiseptic agent against the bacteria.