Abstract: System, methods, and other embodiments described herein relate to autonomous assessment and treatment of a patient. In one embodiment, a method includes, responsive to acquiring, in a managing device, sensor data characterizing a condition of the patient, determining a diagnosis for the condition according to a correlation of the sensor data with a subset of markers. The method includes selecting, using a treatment model, a treatment algorithm from a set of treatment algorithms for performing therapeutic delivery using a robotic device. The method includes causing the robotic device to perform the therapeutic delivery according to the treatment algorithm selected by the treatment model.