Patents Assigned to National Taiwan Ocean University
  • Publication number: 20120276526
    Abstract: The present invention relates to a method for monitoring and recording a viral infection process, which is characterized by providing a microcantilever detection device, which comprises a microcantilever comprising a contact area having an macromolecular material attached thereon; loading host cells to the contact area to allow the host cells to be attached to the macromolecular material; loading virus to the contact area to make the virus to contact the host cells attached thereto whereby a deflection level of the microcantilever is produced; and recording the deflection level in a time course manner so as to obtain a deflection curve that can be used as a basis for monitoring and recording the viral infection process. The method of the invention can also be used for screen for an agent that inhibits virus infection.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 1, 2012
    Applicant: National Taiwan Ocean University
    Inventors: Chih-Wei Wu, Chang-Jer Wu, Shih-Hao Huang, Sheng-Ping Chang
  • Publication number: 20120190007
    Abstract: The present invention relates to a method and system for monitoring and recording a viral infection process and that for screening vaccines, which is characterized by providing a microcantilever detection device, which comprises a microcantilever comprising a contact area having an macromolecular material attached thereon; allowing host cell to be attached to the macromolecular material; allowing a sample containing a test virus or vaccine to be loaded into the contact area to make the test virus or vaccine to contact the host cells attached to the macromolecular material so as to produce a deflection of the microcantilever; and recording the deflection in a time course manner so as to obtain a deflection profile that can used as a basis for determining the viral infection process or the potential efficacy of the vaccines.
    Type: Application
    Filed: July 19, 2011
    Publication date: July 26, 2012
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: CHIH-WEI WU, CHANG-JER WU, SHIH-HAO HUANG, SHENG-PING CHANG
  • Publication number: 20120101573
    Abstract: A mechanical heart valve apparatus includes a loop-shaped frame defining a valve opening and formed with a pair of transverse slot units and a pair of longitudinal slots; and a pair of valve plates mounted on the loop-shaped frame. Each of the valve plates includes a pair of first studs that are slidably and respectively inserted into the transverse slot units, and a second stud that is slidably inserted into a respective one of the longitudinal slots. The valve plates are pivoted to each other so as to be rotatable relative to each other between a closed position, in which the second studs are disposed adjacent to upper ends of the longitudinal slots, and an opening position, in which the second studs are disposed adjacent to lower ends of the longitudinal slots.
    Type: Application
    Filed: May 9, 2011
    Publication date: April 26, 2012
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Chau-Chang Chou, Te-Chun Wu
  • Patent number: 8096784
    Abstract: A bi-directional continuous peristaltic micro-pump is described. The micro-pump comprises: a substrate, an actuating mechanism and a fluid channel. The actuating mechanism comprises: a first slanted membrane the thickness of which increases progressively from left to right, a first chamber formed between the first slanted membrane and the substrate; and a second slanted membrane, the thickness of which decreases progressively from left to right, the second slanted membrane being located to the first slanted membrane's right side and parallel to the first slanted membrane with a space between the two membranes, a second chamber formed between the second slanted membrane and the substrate. By inflating the first chamber and the second chamber, the first slanted membrane and the second slanted membrane generate a continuous sweeping motion to force the working fluid to flow.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: January 17, 2012
    Assignee: National Taiwan Ocean University
    Inventors: Jyh-Jong Sheen, Shang-Chian Su
  • Publication number: 20110259477
    Abstract: A laminated structure by internal oxidation includes an alloy coating layer structured as columnar grains. The alloy coating layer includes a first metal element and a second metal element, wherein the first metal element is oxidized more easily than the second metal element. The surface layer portion of the alloy coating layer has a plurality of oxide layers and a plurality of metal layers stacked alternately with each other. The material of the oxide layers includes the oxide of the first metal element and the material of the metal layers includes the second metal element.
    Type: Application
    Filed: November 24, 2010
    Publication date: October 27, 2011
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Yung-I Chen, Rong-Tan Huang, Bing-Nan Tsai
  • Publication number: 20110182976
    Abstract: This invention relates to a DNA vaccine preparation in a patch against virus infection comprising a DNA construct incorporated in a liposome, wherein the ratio of DNA to liposome is from 1:1 to 1:10; wherein the DNA vaccine preparation is preferably administrated after a pretreatment with alpha hydroxyl acids.
    Type: Application
    Filed: January 28, 2010
    Publication date: July 28, 2011
    Applicant: National Taiwan Ocean University
    Inventors: Chang-Jer Wu, Jing-Yan Cheng, Han-Ning Huang
  • Publication number: 20100323407
    Abstract: A manufacturing method of separating and purifying neoagarooligosaccharides having degrees of polymerization of 2-22 includes the steps of adding crude enzyme solutions with agarases produced by Pseudomonas vesicularis MA103 and Aeromonas salmonicida MAEF108, respectively, into an agar polysaccharide extract solution, and obtaining a neoagarooligosaccharides solution after a hydrolysis on the algal polysaccharide (such as agar) is performed; performing a separation to the neoagarooligosaccharides solution by a ultrafiltration (UF) system to obtain a neoagarooligosaccharide eluent; performing a separation to the neoagarooligosaccharide eluent by a semi-preparative high-performance liquid chromatography system equipped with a molecule size exclusion chromatography function to obtain the neoagarooligosaccharides having the degrees of polymerization from 2 to 22; and using a fraction collector to collect the neoagarooligosaccharides, and obtaining purified single neoagarooligosaccharide products with different mo
    Type: Application
    Filed: June 18, 2009
    Publication date: December 23, 2010
    Applicant: National Taiwan Ocean University
    Inventors: Chorng-Liang Pan, Bartosz Kazlowski, Yuan-Tih Ko, Zwe-Ling Kong, Shao-Chi Wu, Fu-Jin Wang
  • Patent number: 7710309
    Abstract: A method for small-scale fishing boat to avoid ship collision includes the steps of: (1) equipping the small-scale fishing boat with a radar signal receiver for scanning and receiving radar signals transmitted by other ships within the receiving range of the radar signal receiver; (2) using a monitoring computer having a Marine Geographic Information System (Marine GIS) installed thereon to obtain at real time information about the distance, bearings, and etc. of other approaching ships in order to monitor the dynamic conditions of the approaching ships within the fishing boat's operating water area; and (3) actuating a collision warning mechanism based on the intensities of received radar signals when there is more than one approaching ship, so that the small-scale fishing boat can timely receive a collision warning to reduce the risk of collision and maintain safe and smooth voyage on the sea.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: May 4, 2010
    Assignee: National Taiwan Ocean University
    Inventors: Sheng Long Kao, Ming An Lee
  • Publication number: 20100104860
    Abstract: A cemented tungsten carbide-based material includes: a cemented tungsten carbide substrate having a chromized layer that contains a tungsten carbide and a chromium carbide; and a diamond film formed on said chromized layer. A method for making the cemented tungsten carbide-based material involves subjecting a cemented tungsten carbide substrate to chromization so as to form the cemented tungsten carbide substrate with a chromized layer that contains a tungsten carbide and a chromium carbide; and forming a diamond film on the chromized layer.
    Type: Application
    Filed: April 27, 2009
    Publication date: April 29, 2010
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Chau-Chang Chou, Jyh-Wei Lee, Yen-Yi Chen, Hsin-Han Lin
  • Publication number: 20090263264
    Abstract: A bidirectional continuous peristaltic micro-pump is described. The micro-pump comprises: a substrate, an actuating mechanism and a fluid channel. The actuating mechanism comprises: a first slanted membrane the thickness of which increases progressively from left to right, a first chamber formed between the first slanted membrane and the substrate; and a second slanted membrane, the thickness of which decreases progressively from left to right, the second slanted membrane being located to the first slanted membrane's right side and parallel to the first slanted membrane with a space between the two membranes, a second chamber formed between the second slanted membrane and the substrate. By inflating the first chamber and the second chamber, the first slanted membrane and the second slanted membrane generate a continuous sweeping motion to force the working fluid to flow.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 22, 2009
    Applicant: National Taiwan Ocean University
    Inventors: Jyh-Jong Sheen, Shang-Chian Su
  • Publication number: 20090167592
    Abstract: A method for small-scale fishing boat to avoid ship collision includes the steps of: (1) equipping the small-scale fishing boat with a radar signal receiver for scanning and receiving radar signals transmitted by other ships within the receiving range of the radar signal receiver; (2) using a monitoring computer having a Marine Geographic Information System (Marine GIS) installed thereon to obtain at real time information about the distance, bearings, and etc. of other approaching ships in order to monitor the dynamic conditions of the approaching ships within the fishing boat's operating water area; and (3) actuating a collision warning mechanism based on the intensities of received radar signals when there is more than one approaching ship, so that the small-scale fishing boat can timely receive a collision warning to reduce the risk of collision and maintain safe and smooth voyage on the sea.
    Type: Application
    Filed: December 9, 2008
    Publication date: July 2, 2009
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Sheng Long KAO, Ming An Lee
  • Publication number: 20090127243
    Abstract: A method for bonding two pieces of a glassy metal includes:(a) partially immersing the two pieces of the glassy metal in a liquid cooling medium; and (b) welding the two pieces of the glassy metal, which are cooled by the cooling medium at the same time, using pulsed electric arc techniques. The cooling medium provides a cooling rate that is sufficient to prevent crystallization in melted portions of the two pieces of the glassy metal from occurring during welding.
    Type: Application
    Filed: February 5, 2008
    Publication date: May 21, 2009
    Applicant: National Taiwan Ocean University
    Inventors: Shing-Hoa Wang, Pei-Hung Kuo, Yu-Lon Lin, Hsiao-Tsung Tsang, Po-Kay Chiu, Hung-Yin Tsai
  • Publication number: 20080226740
    Abstract: Disclosed herein are marine algal extracts containing marine algal polysaccharides of low degree polymerization, and nanoparticles fabricated from the extracts. Preparation processes and applications of the marine algal extracts and the nanoparticles are also disclosed.
    Type: Application
    Filed: September 12, 2007
    Publication date: September 18, 2008
    Applicant: NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Rong-Huei Chen, Szu-Kai Chen, Wei-Yu Chen, Szu-Hui Chen, Kun-Chi Huang, Chia-Sui Hsu, Yo-Ru Hsu, Shi-Wei Bai
  • Publication number: 20080128055
    Abstract: An thin film alloy based on chemical elements with high glass forming ability is disclosed. The alloy is deposited as a thin film from a source of substantially the same chemical composition. Within the deposited thin film, amorphization is induced extensively up to decades of micrometers in size during controlled annealing. Such controllable extensive amorphization throughout the thin film is useful to regulate the proportion of amorphous phase to crystalline phase, establish the structure/property relationships and thus tailor specific properties.
    Type: Application
    Filed: February 4, 2008
    Publication date: June 5, 2008
    Applicant: National Taiwan Ocean University
    Inventors: Jinn P. Chu, Chun-Hsin Kuo, Chang-Ting Lo
  • Publication number: 20050028900
    Abstract: An thin film alloy based on chemical elements with high glass forming ability is disclosed. The alloy is deposited as a thin film from a source of substantially the same chemical composition. Within the deposited thin film, amorphization is induced extensively up to decades of micrometers in size during controlled annealing. Such controllable extensive amorphization throughout the thin film is useful to regulate the proportion of amorphous phase to crystalline phase, establish the structure/property relationships and thus tailor specific properties.
    Type: Application
    Filed: July 26, 2004
    Publication date: February 10, 2005
    Applicant: National Taiwan Ocean University
    Inventors: Jinn Chu, Chun-Hsin Kuo, Chang-Ting Lo