Patents Assigned to National Taiwan Ocean University
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Publication number: 20120276526Abstract: The present invention relates to a method for monitoring and recording a viral infection process, which is characterized by providing a microcantilever detection device, which comprises a microcantilever comprising a contact area having an macromolecular material attached thereon; loading host cells to the contact area to allow the host cells to be attached to the macromolecular material; loading virus to the contact area to make the virus to contact the host cells attached thereto whereby a deflection level of the microcantilever is produced; and recording the deflection level in a time course manner so as to obtain a deflection curve that can be used as a basis for monitoring and recording the viral infection process. The method of the invention can also be used for screen for an agent that inhibits virus infection.Type: ApplicationFiled: July 12, 2012Publication date: November 1, 2012Applicant: National Taiwan Ocean UniversityInventors: Chih-Wei Wu, Chang-Jer Wu, Shih-Hao Huang, Sheng-Ping Chang
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Publication number: 20120190007Abstract: The present invention relates to a method and system for monitoring and recording a viral infection process and that for screening vaccines, which is characterized by providing a microcantilever detection device, which comprises a microcantilever comprising a contact area having an macromolecular material attached thereon; allowing host cell to be attached to the macromolecular material; allowing a sample containing a test virus or vaccine to be loaded into the contact area to make the test virus or vaccine to contact the host cells attached to the macromolecular material so as to produce a deflection of the microcantilever; and recording the deflection in a time course manner so as to obtain a deflection profile that can used as a basis for determining the viral infection process or the potential efficacy of the vaccines.Type: ApplicationFiled: July 19, 2011Publication date: July 26, 2012Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: CHIH-WEI WU, CHANG-JER WU, SHIH-HAO HUANG, SHENG-PING CHANG
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Publication number: 20120101573Abstract: A mechanical heart valve apparatus includes a loop-shaped frame defining a valve opening and formed with a pair of transverse slot units and a pair of longitudinal slots; and a pair of valve plates mounted on the loop-shaped frame. Each of the valve plates includes a pair of first studs that are slidably and respectively inserted into the transverse slot units, and a second stud that is slidably inserted into a respective one of the longitudinal slots. The valve plates are pivoted to each other so as to be rotatable relative to each other between a closed position, in which the second studs are disposed adjacent to upper ends of the longitudinal slots, and an opening position, in which the second studs are disposed adjacent to lower ends of the longitudinal slots.Type: ApplicationFiled: May 9, 2011Publication date: April 26, 2012Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: Chau-Chang Chou, Te-Chun Wu
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Patent number: 8096784Abstract: A bi-directional continuous peristaltic micro-pump is described. The micro-pump comprises: a substrate, an actuating mechanism and a fluid channel. The actuating mechanism comprises: a first slanted membrane the thickness of which increases progressively from left to right, a first chamber formed between the first slanted membrane and the substrate; and a second slanted membrane, the thickness of which decreases progressively from left to right, the second slanted membrane being located to the first slanted membrane's right side and parallel to the first slanted membrane with a space between the two membranes, a second chamber formed between the second slanted membrane and the substrate. By inflating the first chamber and the second chamber, the first slanted membrane and the second slanted membrane generate a continuous sweeping motion to force the working fluid to flow.Type: GrantFiled: April 16, 2008Date of Patent: January 17, 2012Assignee: National Taiwan Ocean UniversityInventors: Jyh-Jong Sheen, Shang-Chian Su
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Publication number: 20110259477Abstract: A laminated structure by internal oxidation includes an alloy coating layer structured as columnar grains. The alloy coating layer includes a first metal element and a second metal element, wherein the first metal element is oxidized more easily than the second metal element. The surface layer portion of the alloy coating layer has a plurality of oxide layers and a plurality of metal layers stacked alternately with each other. The material of the oxide layers includes the oxide of the first metal element and the material of the metal layers includes the second metal element.Type: ApplicationFiled: November 24, 2010Publication date: October 27, 2011Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: Yung-I Chen, Rong-Tan Huang, Bing-Nan Tsai
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Publication number: 20110182976Abstract: This invention relates to a DNA vaccine preparation in a patch against virus infection comprising a DNA construct incorporated in a liposome, wherein the ratio of DNA to liposome is from 1:1 to 1:10; wherein the DNA vaccine preparation is preferably administrated after a pretreatment with alpha hydroxyl acids.Type: ApplicationFiled: January 28, 2010Publication date: July 28, 2011Applicant: National Taiwan Ocean UniversityInventors: Chang-Jer Wu, Jing-Yan Cheng, Han-Ning Huang
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Publication number: 20100323407Abstract: A manufacturing method of separating and purifying neoagarooligosaccharides having degrees of polymerization of 2-22 includes the steps of adding crude enzyme solutions with agarases produced by Pseudomonas vesicularis MA103 and Aeromonas salmonicida MAEF108, respectively, into an agar polysaccharide extract solution, and obtaining a neoagarooligosaccharides solution after a hydrolysis on the algal polysaccharide (such as agar) is performed; performing a separation to the neoagarooligosaccharides solution by a ultrafiltration (UF) system to obtain a neoagarooligosaccharide eluent; performing a separation to the neoagarooligosaccharide eluent by a semi-preparative high-performance liquid chromatography system equipped with a molecule size exclusion chromatography function to obtain the neoagarooligosaccharides having the degrees of polymerization from 2 to 22; and using a fraction collector to collect the neoagarooligosaccharides, and obtaining purified single neoagarooligosaccharide products with different moType: ApplicationFiled: June 18, 2009Publication date: December 23, 2010Applicant: National Taiwan Ocean UniversityInventors: Chorng-Liang Pan, Bartosz Kazlowski, Yuan-Tih Ko, Zwe-Ling Kong, Shao-Chi Wu, Fu-Jin Wang
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Patent number: 7710309Abstract: A method for small-scale fishing boat to avoid ship collision includes the steps of: (1) equipping the small-scale fishing boat with a radar signal receiver for scanning and receiving radar signals transmitted by other ships within the receiving range of the radar signal receiver; (2) using a monitoring computer having a Marine Geographic Information System (Marine GIS) installed thereon to obtain at real time information about the distance, bearings, and etc. of other approaching ships in order to monitor the dynamic conditions of the approaching ships within the fishing boat's operating water area; and (3) actuating a collision warning mechanism based on the intensities of received radar signals when there is more than one approaching ship, so that the small-scale fishing boat can timely receive a collision warning to reduce the risk of collision and maintain safe and smooth voyage on the sea.Type: GrantFiled: December 9, 2008Date of Patent: May 4, 2010Assignee: National Taiwan Ocean UniversityInventors: Sheng Long Kao, Ming An Lee
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Publication number: 20100104860Abstract: A cemented tungsten carbide-based material includes: a cemented tungsten carbide substrate having a chromized layer that contains a tungsten carbide and a chromium carbide; and a diamond film formed on said chromized layer. A method for making the cemented tungsten carbide-based material involves subjecting a cemented tungsten carbide substrate to chromization so as to form the cemented tungsten carbide substrate with a chromized layer that contains a tungsten carbide and a chromium carbide; and forming a diamond film on the chromized layer.Type: ApplicationFiled: April 27, 2009Publication date: April 29, 2010Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: Chau-Chang Chou, Jyh-Wei Lee, Yen-Yi Chen, Hsin-Han Lin
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Publication number: 20090263264Abstract: A bidirectional continuous peristaltic micro-pump is described. The micro-pump comprises: a substrate, an actuating mechanism and a fluid channel. The actuating mechanism comprises: a first slanted membrane the thickness of which increases progressively from left to right, a first chamber formed between the first slanted membrane and the substrate; and a second slanted membrane, the thickness of which decreases progressively from left to right, the second slanted membrane being located to the first slanted membrane's right side and parallel to the first slanted membrane with a space between the two membranes, a second chamber formed between the second slanted membrane and the substrate. By inflating the first chamber and the second chamber, the first slanted membrane and the second slanted membrane generate a continuous sweeping motion to force the working fluid to flow.Type: ApplicationFiled: April 16, 2008Publication date: October 22, 2009Applicant: National Taiwan Ocean UniversityInventors: Jyh-Jong Sheen, Shang-Chian Su
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Publication number: 20090167592Abstract: A method for small-scale fishing boat to avoid ship collision includes the steps of: (1) equipping the small-scale fishing boat with a radar signal receiver for scanning and receiving radar signals transmitted by other ships within the receiving range of the radar signal receiver; (2) using a monitoring computer having a Marine Geographic Information System (Marine GIS) installed thereon to obtain at real time information about the distance, bearings, and etc. of other approaching ships in order to monitor the dynamic conditions of the approaching ships within the fishing boat's operating water area; and (3) actuating a collision warning mechanism based on the intensities of received radar signals when there is more than one approaching ship, so that the small-scale fishing boat can timely receive a collision warning to reduce the risk of collision and maintain safe and smooth voyage on the sea.Type: ApplicationFiled: December 9, 2008Publication date: July 2, 2009Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: Sheng Long KAO, Ming An Lee
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Publication number: 20090127243Abstract: A method for bonding two pieces of a glassy metal includes:(a) partially immersing the two pieces of the glassy metal in a liquid cooling medium; and (b) welding the two pieces of the glassy metal, which are cooled by the cooling medium at the same time, using pulsed electric arc techniques. The cooling medium provides a cooling rate that is sufficient to prevent crystallization in melted portions of the two pieces of the glassy metal from occurring during welding.Type: ApplicationFiled: February 5, 2008Publication date: May 21, 2009Applicant: National Taiwan Ocean UniversityInventors: Shing-Hoa Wang, Pei-Hung Kuo, Yu-Lon Lin, Hsiao-Tsung Tsang, Po-Kay Chiu, Hung-Yin Tsai
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Publication number: 20080226740Abstract: Disclosed herein are marine algal extracts containing marine algal polysaccharides of low degree polymerization, and nanoparticles fabricated from the extracts. Preparation processes and applications of the marine algal extracts and the nanoparticles are also disclosed.Type: ApplicationFiled: September 12, 2007Publication date: September 18, 2008Applicant: NATIONAL TAIWAN OCEAN UNIVERSITYInventors: Rong-Huei Chen, Szu-Kai Chen, Wei-Yu Chen, Szu-Hui Chen, Kun-Chi Huang, Chia-Sui Hsu, Yo-Ru Hsu, Shi-Wei Bai
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Publication number: 20080128055Abstract: An thin film alloy based on chemical elements with high glass forming ability is disclosed. The alloy is deposited as a thin film from a source of substantially the same chemical composition. Within the deposited thin film, amorphization is induced extensively up to decades of micrometers in size during controlled annealing. Such controllable extensive amorphization throughout the thin film is useful to regulate the proportion of amorphous phase to crystalline phase, establish the structure/property relationships and thus tailor specific properties.Type: ApplicationFiled: February 4, 2008Publication date: June 5, 2008Applicant: National Taiwan Ocean UniversityInventors: Jinn P. Chu, Chun-Hsin Kuo, Chang-Ting Lo
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Publication number: 20050028900Abstract: An thin film alloy based on chemical elements with high glass forming ability is disclosed. The alloy is deposited as a thin film from a source of substantially the same chemical composition. Within the deposited thin film, amorphization is induced extensively up to decades of micrometers in size during controlled annealing. Such controllable extensive amorphization throughout the thin film is useful to regulate the proportion of amorphous phase to crystalline phase, establish the structure/property relationships and thus tailor specific properties.Type: ApplicationFiled: July 26, 2004Publication date: February 10, 2005Applicant: National Taiwan Ocean UniversityInventors: Jinn Chu, Chun-Hsin Kuo, Chang-Ting Lo