Abstract: An image processing system includes an ophthalmoscope device and a processor. The ophthalmoscope device is configured to obtain a color fundus image. The processor is configured to receive the color fundus image; generate a blood vessel segmentation image that corresponds to the color fundus image using a computer vision algorithm or a deep learning model; preprocess the color fundus image and the blood vessel segmentation image to obtain an initial input image; and input the initial input image into a convolutional neural network. The convolutional neural network outputs a value. In addition, the processor generates fundus image analysis information from the cup-to-disc ratio and the value.

Abstract: A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.

Abstract: The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images.

Abstract: The present invention provides a supporting member and a supporting member assembly including the same to be implanted into or between a subject's bones, and a template plug and a tamper corresponding to the supporting member. The supporting member comprises a main body; a first connecting portion and a second connecting portion formed on the upper and lower sides of the main body respectively and forming a dovetail joint with each other; and a guiding structure formed at a side of the main body and including guiding holes as well as a buffer groove for mating with an external template plug. The supporting members of the invention can be sequentially implanted and connected into a bone or between two connected bones, and improve the defect of the conventional one-size giant implants injuring the surrounding nerves.

Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.

Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.

Abstract: The disclosure provides an eye state assessment method and an electronic device. The method includes: obtaining an optic disc image area from a first fundus photography and generating multiple optic cup-to-disc ratio assessment results by multiple first models based on the optic disc image area; obtaining a first assessment result of an eye based on the optic cup-to-disc ratio assessment results; performing multiple data augmentation operations on the first fundus photography to generate multiple second fundus photographies; generating multiple retinal nerve fiber layer (RNFL) defect assessment results by multiple second models based on the second fundus photographies; obtaining a second assessment result of the eye based on the RNFL defect assessment results; and obtaining an optic nerve assessment result of the eye based on the first assessment result and the second assessment result.

Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.

Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.

Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.

Abstract: A tube-docking holding device includes a first connector bracket and a second connector bracket. The first connector bracket includes two shells. When the two shells are closed, a first accommodation space is surrounded for fixing a portion of a first connector assembly of a catheter. The second connector bracket includes a base body and a cover body. The base body includes a first inner shell and a first outer shell. The cover body includes a second inner shell and a second outer shell. When the cover body and the base body are closed, the first inner shell and the second inner shell surround and define a second accommodation space for fixing a portion of a second connector assembly of a dialysate tube. An interconnected guiding space is formed between the first inner shell and the first outer shell and between the second inner shell and the second outer shell.

Abstract: The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images.

Abstract: A radiofrequency ablation electrode needle includes at least one first segment and at least two second segments. The at least one first segment and the at least two second segments are exposed on a surface of the needle body. An impedance of the at least one first segment is smaller than an impedance of the at least two second segments and at least one of the at least one first segment is disposed between two immediately adjacent ones of the at least two second segments. Besides, the radiofrequency ablation electrode needle is a monopolar electrode needle.

Abstract: An osteo-implant is provided, having a fixing segment and an implant end. The fixing segment is provided with a thread and at least one bone healing chamber. The bone healing chamber is located at a thread root of the thread. The bone healing chamber is a chamber inwardly depressed from a surface of the fixing segment. The fixing segment has a central axis. In the same section of the fixing segment, an area of a section, which is parallel to and passes through the central axis, of the at least one bone healing chamber closer to the implant end is smaller.

Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient.

Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.

Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.

Abstract: A needle guide system is provided. The needle guide system includes a puncture device, an ultrasound transducer, a first orientation detector, a second orientation detector, a proximity detector and a processor. The ultrasound transducer is configured to obtain an ultrasound image. The first orientation detector is disposed on the puncture device, and the second orientation detector is disposed on the ultrasound transducer. The proximity detector is disposed on at least one of the puncture device and the ultrasound transducer, configured to obtain a relative distance between the puncture device and the ultrasound transducer. The processor is configured to obtain a spatial relationship between the puncture device and the ultrasound transducer by using the first orientation detector, the second orientation detector, and the proximity detector, and predict a trajectory of the puncture device in the ultrasound image according to the spatial relationship.

Abstract: A bionic apparatus is provided. The bionic apparatus includes a flexible portion having a plurality of pores, a rigid portion connected with the flexible portion, and a supporting element disposed in the flexible portion. The pore size of each pore is between 50 ?m to 500 ?m. The flexible portion, the rigid portion and the supporting element are one-piece formed by a additive manufacturing process.

Abstract: A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.