Patents Assigned to National Taiwan University Hospital
  • Patent number: 11651588
    Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: May 16, 2023
    Assignees: NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Chao-Yuan Yeh, Wen-Chien Chou, Cheng-Kun Yang
  • Publication number: 20230128432
    Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.
    Type: Application
    Filed: June 5, 2020
    Publication date: April 27, 2023
    Applicants: AETHERAI IP HOLDING LLC, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Chao-Yuan YEH, Wen-Chien CHOU, Cheng-Kun YANG
  • Publication number: 20230066166
    Abstract: The disclosure provides an eye state assessment method and an electronic device. The method includes: obtaining an optic disc image area from a first fundus photography and generating multiple optic cup-to-disc ratio assessment results by multiple first models based on the optic disc image area; obtaining a first assessment result of an eye based on the optic cup-to-disc ratio assessment results; performing multiple data augmentation operations on the first fundus photography to generate multiple second fundus photographies; generating multiple retinal nerve fiber layer (RNFL) defect assessment results by multiple second models based on the second fundus photographies; obtaining a second assessment result of the eye based on the RNFL defect assessment results; and obtaining an optic nerve assessment result of the eye based on the first assessment result and the second assessment result.
    Type: Application
    Filed: October 21, 2021
    Publication date: March 2, 2023
    Applicants: Acer Incorporated, National Taiwan University Hospital
    Inventors: Yi-Jin Huang, Chien-Hung Li, Wei-Hao Chang, Hung-Sheng Hsu, Ming-Chi Kuo, Jehn-Yu Huang
  • Patent number: 11351037
    Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: June 7, 2022
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Fang-Jie Jang, Pei-I Tsai, De-Yau Lin, An-Li Chen, Fon-Yih Tsuang, Chih-Chieh Huang, Hsin-Hsin Shen
  • Publication number: 20210137698
    Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.
    Type: Application
    Filed: December 30, 2019
    Publication date: May 13, 2021
    Applicants: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Fang-Jie JANG, Pei-I TSAI, De-Yau LIN, An-Li CHEN, Fon-Yih TSUANG, Chih-Chieh HUANG, Hsin-Hsin SHEN
  • Patent number: 10973647
    Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: April 13, 2021
    Assignees: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Pei-I Tsai, Hsin-Hsin Shen, Kuo-Yi Yang, De-Yau Lin, Yi-Hung Wen, Chih-Chieh Huang, Wei-Luan Fan, Pei-Yu Chen, Ching-Chi Hsu
  • Patent number: 10912936
    Abstract: A tube-docking holding device includes a first connector bracket and a second connector bracket. The first connector bracket includes two shells. When the two shells are closed, a first accommodation space is surrounded for fixing a portion of a first connector assembly of a catheter. The second connector bracket includes a base body and a cover body. The base body includes a first inner shell and a first outer shell. The cover body includes a second inner shell and a second outer shell. When the cover body and the base body are closed, the first inner shell and the second inner shell surround and define a second accommodation space for fixing a portion of a second connector assembly of a dialysate tube. An interconnected guiding space is formed between the first inner shell and the first outer shell and between the second inner shell and the second outer shell.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: February 9, 2021
    Assignees: National Formosa University, National Taiwan University Hospital Yun-Lin Branch
    Inventors: Sung-An Lin, I-En Lin, Feng-Jung Yang, Hao-Ting Chiang
  • Publication number: 20210007606
    Abstract: The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images.
    Type: Application
    Filed: July 9, 2020
    Publication date: January 14, 2021
    Applicants: COMPAL ELECTRONICS, INC., National Taiwan University Hospital
    Inventors: Tung-Hung Su, Cheng-Fu Chou, Shann-Ching Chen
  • Patent number: 10888372
    Abstract: A radiofrequency ablation electrode needle includes at least one first segment and at least two second segments. The at least one first segment and the at least two second segments are exposed on a surface of the needle body. An impedance of the at least one first segment is smaller than an impedance of the at least two second segments and at least one of the at least one first segment is disposed between two immediately adjacent ones of the at least two second segments. Besides, the radiofrequency ablation electrode needle is a monopolar electrode needle.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: January 12, 2021
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Hui-Hsin Lu, Meng-Han Tsai, Kai-Wen Huang, Jo-Ping Lee, Wen-Yang Chou
  • Patent number: 10806584
    Abstract: An osteo-implant is provided, having a fixing segment and an implant end. The fixing segment is provided with a thread and at least one bone healing chamber. The bone healing chamber is located at a thread root of the thread. The bone healing chamber is a chamber inwardly depressed from a surface of the fixing segment. The fixing segment has a central axis. In the same section of the fixing segment, an area of a section, which is parallel to and passes through the central axis, of the at least one bone healing chamber closer to the implant end is smaller.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: October 20, 2020
    Assignees: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Chih-Chieh Huang, Pei-I Tsai, Hsin-Hsin Shen, Yi-Hung Wen, Kuo-Yi Yang, Wei-Luan Fan, Jui-Sheng Sun, Nien-Ti Tsou
  • Patent number: 10786370
    Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: September 29, 2020
    Assignees: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Ching-Chuan Jiang, Fang-Jie Jang, Ming-Chia Yang, Yun-Han Lin
  • Publication number: 20190388230
    Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.
    Type: Application
    Filed: December 19, 2018
    Publication date: December 26, 2019
    Applicants: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Pei-I Tsai, Hsin-Hsin Shen, Kuo-Yi Yang, De-Yau Lin, Yi-Hung Wen, Chih-Chieh Huang, Wei-Luan Fan, Pei-Yu Chen, Ching-Chi Hsu
  • Patent number: 10507041
    Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: December 17, 2019
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Pei-Yi Tsai, Chih-Chieh Huang, Yi-Hung Wen, Hsin-Hsin Shen, Yi-Hung Lin, De-Yau Lin, Jui-Sheng Sun, Chuan-Sheng Chuang, An-Li Chen, Ching-Chih Lin
  • Patent number: 10376235
    Abstract: A needle guide system is provided. The needle guide system includes a puncture device, an ultrasound transducer, a first orientation detector, a second orientation detector, a proximity detector and a processor. The ultrasound transducer is configured to obtain an ultrasound image. The first orientation detector is disposed on the puncture device, and the second orientation detector is disposed on the ultrasound transducer. The proximity detector is disposed on at least one of the puncture device and the ultrasound transducer, configured to obtain a relative distance between the puncture device and the ultrasound transducer. The processor is configured to obtain a spatial relationship between the puncture device and the ultrasound transducer by using the first orientation detector, the second orientation detector, and the proximity detector, and predict a trajectory of the puncture device in the ultrasound image according to the spatial relationship.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: August 13, 2019
    Assignees: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Wan-Hsin Hsieh, Hui-Hsin Lu, Chih-Yuan Wang
  • Patent number: 10357297
    Abstract: A bionic apparatus is provided. The bionic apparatus includes a flexible portion having a plurality of pores, a rigid portion connected with the flexible portion, and a supporting element disposed in the flexible portion. The pore size of each pore is between 50 ?m to 500 ?m. The flexible portion, the rigid portion and the supporting element are one-piece formed by a additive manufacturing process.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: July 23, 2019
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Pei-Yi Tsai, Chih-Chieh Huang, Yi-Hung Wen, Hsin-Hsin Shen, Yi-Hung Lin, De-Yau Lin, Jui-Sheng Sun, Chuan-Sheng Chuang, An-Li Chen, Ching-Chih Lin
  • Publication number: 20190203195
    Abstract: A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 4, 2019
    Applicants: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Cheng-Tai Chen, Chien-An Chen, Wen-Ting Chiang, Su-Feng Chiu, Pei-Shin Jiang, Jih-Luh Tang, Chien-Ting Lin, Xuan-Hui Lin
  • Publication number: 20190201203
    Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient.
    Type: Application
    Filed: December 28, 2017
    Publication date: July 4, 2019
    Applicants: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Ching-Chuan Jiang, Fang-Jie Jang, Ming-Chia Yang, Yun-Han Lin
  • Publication number: 20190201061
    Abstract: An expandable orthopedic implant includes a casing pipe, a shaft, a first expandable element and a first link lever. The casing pipe has a first opening, a second opening and an axis passing through the first and second opening. The casing pipe sheathes one end of the shaft, and the other end of the shaft has a top portion disposed out of the first opening. The first expandable element has a first terminal pivoted on the casing pipe and a second terminal. The first link lever has a proximal end pivoted to the top portion and a distal end pivoted to the second terminal. When the top portion is driven moving away from the first opening along an extending direction of the axis, the first link-lever can be pushed by the shaft to enact the second terminal moving away from the axis along a direction perpendicular to the axis.
    Type: Application
    Filed: December 28, 2017
    Publication date: July 4, 2019
    Applicants: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, National Taiwan University Hospital
    Inventors: Pei-I TSAI, Hsin-Hsin SHEN, Kuo-Yi YANG, Shih-Ping LIN, Jui-Sheng SUN, Chih-Yu CHEN, Yu-Tsung CHIU, Chun-Ti CHEN, De-Yau LIN, An-Li CHEN
  • Patent number: 10245014
    Abstract: Provided is a device of automatic mechanical wound opener for head and neck surgery. The device includes a wound opener including: a fixed unit and a plurality of drawing units, and at least one of the drawing units being movably connected on the fixed unit, wherein each of the drawing units includes a first arm, a second arm, and a blade connected to the second arm; wherein the first arm is connected to the fixed unit by one end thereof and to the second arm by the other end thereof; the second arm can be adjusted to an needed included angle relative to the first arm; and at least one of the blades includes an extension plate connected to an end of a plate part of the blade, and the extension plate is connected to the second arm for shortening the spacing between two blades.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: April 2, 2019
    Assignee: NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventor: Tsung-Lin Yang
  • Patent number: 10172699
    Abstract: The present invention provides an implant for pelvic organ prolapse support, comprising an implant for anterior vaginal wall prolapse support which comprises first body having a first angle and a second angle, a pair of first arms and a pair of second arms. The implant for pelvic organ prolapse support of the present invention can treat cystocele and stress urinary incontinence simultaneously, and can optionally combine with an implant for posterior vaginal wall prolapse support and an auxiliary supporter to treat cystocele, stress urinary incontinence, enterocele, uterine prolapse, rectocele prolapse, anal prolapse, and vaginal vault prolapse at one time.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: January 8, 2019
    Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL TAIWAN UNIVERSITY HOSPITAL
    Inventors: Ho-Hsiung Lin, Ting-Chen Chang