Patents Assigned to National Taiwan University Hospital
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Patent number: 11651588Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.Type: GrantFiled: June 5, 2020Date of Patent: May 16, 2023Assignees: NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Chao-Yuan Yeh, Wen-Chien Chou, Cheng-Kun Yang
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Publication number: 20230128432Abstract: Disclosed are an object detection method and a convolution neural network. The method is performed through hierarchical architecture of the CNN and includes extracting groups of augmented feature maps from an input image through a backbone and two other groups of feature maps, identifying positive and negative samples with an IOU-based sampling scheme to be proposals for foreground and background through a proposal-sampling classifier, mapping the proposals to regions on the groups of augmented feature maps through the region proposal module, pooling the regions to fixed scale feature maps based on ROI aligning, fusing the fixed scale feature maps, and flattening the fused feature maps to generate an ROI feature vector through an ROI aligner for object classification and box regression. Because extracted features in the groups of augmented feature maps range from spatially-rich features to semantically-rich features, enhanced performance in object classification and box regression can be secured.Type: ApplicationFiled: June 5, 2020Publication date: April 27, 2023Applicants: AETHERAI IP HOLDING LLC, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Chao-Yuan YEH, Wen-Chien CHOU, Cheng-Kun YANG
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Publication number: 20230066166Abstract: The disclosure provides an eye state assessment method and an electronic device. The method includes: obtaining an optic disc image area from a first fundus photography and generating multiple optic cup-to-disc ratio assessment results by multiple first models based on the optic disc image area; obtaining a first assessment result of an eye based on the optic cup-to-disc ratio assessment results; performing multiple data augmentation operations on the first fundus photography to generate multiple second fundus photographies; generating multiple retinal nerve fiber layer (RNFL) defect assessment results by multiple second models based on the second fundus photographies; obtaining a second assessment result of the eye based on the RNFL defect assessment results; and obtaining an optic nerve assessment result of the eye based on the first assessment result and the second assessment result.Type: ApplicationFiled: October 21, 2021Publication date: March 2, 2023Applicants: Acer Incorporated, National Taiwan University HospitalInventors: Yi-Jin Huang, Chien-Hung Li, Wei-Hao Chang, Hung-Sheng Hsu, Ming-Chi Kuo, Jehn-Yu Huang
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Patent number: 11351037Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.Type: GrantFiled: December 30, 2019Date of Patent: June 7, 2022Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Fang-Jie Jang, Pei-I Tsai, De-Yau Lin, An-Li Chen, Fon-Yih Tsuang, Chih-Chieh Huang, Hsin-Hsin Shen
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Publication number: 20210137698Abstract: The disclosure relates to a vertebral body implant including a flexible main body and at least one pedicle screw joint. The flexible main body is an integrally formed single piece having at least one joint-accommodating hole and at least one opening connected to the at least one joint-accommodating hole. The pedicle screw joint is an integrally formed single piece movably accommodated in the at least one joint-accommodating hole.Type: ApplicationFiled: December 30, 2019Publication date: May 13, 2021Applicants: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Fang-Jie JANG, Pei-I TSAI, De-Yau LIN, An-Li CHEN, Fon-Yih TSUANG, Chih-Chieh HUANG, Hsin-Hsin SHEN
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Patent number: 10973647Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.Type: GrantFiled: December 19, 2018Date of Patent: April 13, 2021Assignees: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Pei-I Tsai, Hsin-Hsin Shen, Kuo-Yi Yang, De-Yau Lin, Yi-Hung Wen, Chih-Chieh Huang, Wei-Luan Fan, Pei-Yu Chen, Ching-Chi Hsu
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Patent number: 10912936Abstract: A tube-docking holding device includes a first connector bracket and a second connector bracket. The first connector bracket includes two shells. When the two shells are closed, a first accommodation space is surrounded for fixing a portion of a first connector assembly of a catheter. The second connector bracket includes a base body and a cover body. The base body includes a first inner shell and a first outer shell. The cover body includes a second inner shell and a second outer shell. When the cover body and the base body are closed, the first inner shell and the second inner shell surround and define a second accommodation space for fixing a portion of a second connector assembly of a dialysate tube. An interconnected guiding space is formed between the first inner shell and the first outer shell and between the second inner shell and the second outer shell.Type: GrantFiled: October 1, 2018Date of Patent: February 9, 2021Assignees: National Formosa University, National Taiwan University Hospital Yun-Lin BranchInventors: Sung-An Lin, I-En Lin, Feng-Jung Yang, Hao-Ting Chiang
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Publication number: 20210007606Abstract: The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images.Type: ApplicationFiled: July 9, 2020Publication date: January 14, 2021Applicants: COMPAL ELECTRONICS, INC., National Taiwan University HospitalInventors: Tung-Hung Su, Cheng-Fu Chou, Shann-Ching Chen
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Patent number: 10888372Abstract: A radiofrequency ablation electrode needle includes at least one first segment and at least two second segments. The at least one first segment and the at least two second segments are exposed on a surface of the needle body. An impedance of the at least one first segment is smaller than an impedance of the at least two second segments and at least one of the at least one first segment is disposed between two immediately adjacent ones of the at least two second segments. Besides, the radiofrequency ablation electrode needle is a monopolar electrode needle.Type: GrantFiled: December 14, 2016Date of Patent: January 12, 2021Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Hui-Hsin Lu, Meng-Han Tsai, Kai-Wen Huang, Jo-Ping Lee, Wen-Yang Chou
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Patent number: 10806584Abstract: An osteo-implant is provided, having a fixing segment and an implant end. The fixing segment is provided with a thread and at least one bone healing chamber. The bone healing chamber is located at a thread root of the thread. The bone healing chamber is a chamber inwardly depressed from a surface of the fixing segment. The fixing segment has a central axis. In the same section of the fixing segment, an area of a section, which is parallel to and passes through the central axis, of the at least one bone healing chamber closer to the implant end is smaller.Type: GrantFiled: December 29, 2016Date of Patent: October 20, 2020Assignees: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Chih-Chieh Huang, Pei-I Tsai, Hsin-Hsin Shen, Yi-Hung Wen, Kuo-Yi Yang, Wei-Luan Fan, Jui-Sheng Sun, Nien-Ti Tsou
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Patent number: 10786370Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient.Type: GrantFiled: December 28, 2017Date of Patent: September 29, 2020Assignees: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Ching-Chuan Jiang, Fang-Jie Jang, Ming-Chia Yang, Yun-Han Lin
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Publication number: 20190388230Abstract: An artificial joint includes a first joint assembly and a second joint assembly. The first joint assembly is adapted to be connected to a first bone and has a first contacting surface, wherein the first contacting surface includes a first convex arc surface, a second convex arc surface, and a third convex arc surface. The second joint assembly is adapted to be connected to a second bone and has a second contacting surface, wherein the second contacting surface is in contact with the first contacting surface and includes a first concave arc surface, a second concave arc surface, and a third concave arc surface, and the first concave arc surface, the second concave arc surface, and the third concave arc surface respectively correspond to the first convex arc surface, the second convex arc surface, and the third convex arc surface.Type: ApplicationFiled: December 19, 2018Publication date: December 26, 2019Applicants: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Pei-I Tsai, Hsin-Hsin Shen, Kuo-Yi Yang, De-Yau Lin, Yi-Hung Wen, Chih-Chieh Huang, Wei-Luan Fan, Pei-Yu Chen, Ching-Chi Hsu
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Patent number: 10507041Abstract: A bionic fixing apparatus is provided. The bionic fixing apparatus includes a body having a through hole and at least one slit. The through hole penetrates the body from the top surface to the bottom surface to form a top opening and a bottom opening. An inner diameter of the top opening is larger than an inner diameter of the bottom opening. The slit is connected to the bottom opening and extends upwardly from the bottom surface of the body, such that the body has a flexible bottom portion.Type: GrantFiled: November 26, 2014Date of Patent: December 17, 2019Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Pei-Yi Tsai, Chih-Chieh Huang, Yi-Hung Wen, Hsin-Hsin Shen, Yi-Hung Lin, De-Yau Lin, Jui-Sheng Sun, Chuan-Sheng Chuang, An-Li Chen, Ching-Chih Lin
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Patent number: 10376235Abstract: A needle guide system is provided. The needle guide system includes a puncture device, an ultrasound transducer, a first orientation detector, a second orientation detector, a proximity detector and a processor. The ultrasound transducer is configured to obtain an ultrasound image. The first orientation detector is disposed on the puncture device, and the second orientation detector is disposed on the ultrasound transducer. The proximity detector is disposed on at least one of the puncture device and the ultrasound transducer, configured to obtain a relative distance between the puncture device and the ultrasound transducer. The processor is configured to obtain a spatial relationship between the puncture device and the ultrasound transducer by using the first orientation detector, the second orientation detector, and the proximity detector, and predict a trajectory of the puncture device in the ultrasound image according to the spatial relationship.Type: GrantFiled: December 21, 2016Date of Patent: August 13, 2019Assignees: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Wan-Hsin Hsieh, Hui-Hsin Lu, Chih-Yuan Wang
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Patent number: 10357297Abstract: A bionic apparatus is provided. The bionic apparatus includes a flexible portion having a plurality of pores, a rigid portion connected with the flexible portion, and a supporting element disposed in the flexible portion. The pore size of each pore is between 50 ?m to 500 ?m. The flexible portion, the rigid portion and the supporting element are one-piece formed by a additive manufacturing process.Type: GrantFiled: November 26, 2014Date of Patent: July 23, 2019Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Pei-Yi Tsai, Chih-Chieh Huang, Yi-Hung Wen, Hsin-Hsin Shen, Yi-Hung Lin, De-Yau Lin, Jui-Sheng Sun, Chuan-Sheng Chuang, An-Li Chen, Ching-Chih Lin
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Publication number: 20190203195Abstract: A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.Type: ApplicationFiled: December 21, 2018Publication date: July 4, 2019Applicants: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Cheng-Tai Chen, Chien-An Chen, Wen-Ting Chiang, Su-Feng Chiu, Pei-Shin Jiang, Jih-Luh Tang, Chien-Ting Lin, Xuan-Hui Lin
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Publication number: 20190201203Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient.Type: ApplicationFiled: December 28, 2017Publication date: July 4, 2019Applicants: Industrial Technology Research Institute, National Taiwan University HospitalInventors: Ching-Chuan Jiang, Fang-Jie Jang, Ming-Chia Yang, Yun-Han Lin
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Publication number: 20190201061Abstract: An expandable orthopedic implant includes a casing pipe, a shaft, a first expandable element and a first link lever. The casing pipe has a first opening, a second opening and an axis passing through the first and second opening. The casing pipe sheathes one end of the shaft, and the other end of the shaft has a top portion disposed out of the first opening. The first expandable element has a first terminal pivoted on the casing pipe and a second terminal. The first link lever has a proximal end pivoted to the top portion and a distal end pivoted to the second terminal. When the top portion is driven moving away from the first opening along an extending direction of the axis, the first link-lever can be pushed by the shaft to enact the second terminal moving away from the axis along a direction perpendicular to the axis.Type: ApplicationFiled: December 28, 2017Publication date: July 4, 2019Applicants: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, National Taiwan University HospitalInventors: Pei-I TSAI, Hsin-Hsin SHEN, Kuo-Yi YANG, Shih-Ping LIN, Jui-Sheng SUN, Chih-Yu CHEN, Yu-Tsung CHIU, Chun-Ti CHEN, De-Yau LIN, An-Li CHEN
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Patent number: 10245014Abstract: Provided is a device of automatic mechanical wound opener for head and neck surgery. The device includes a wound opener including: a fixed unit and a plurality of drawing units, and at least one of the drawing units being movably connected on the fixed unit, wherein each of the drawing units includes a first arm, a second arm, and a blade connected to the second arm; wherein the first arm is connected to the fixed unit by one end thereof and to the second arm by the other end thereof; the second arm can be adjusted to an needed included angle relative to the first arm; and at least one of the blades includes an extension plate connected to an end of a plate part of the blade, and the extension plate is connected to the second arm for shortening the spacing between two blades.Type: GrantFiled: July 22, 2016Date of Patent: April 2, 2019Assignee: NATIONAL TAIWAN UNIVERSITY HOSPITALInventor: Tsung-Lin Yang
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Patent number: 10172699Abstract: The present invention provides an implant for pelvic organ prolapse support, comprising an implant for anterior vaginal wall prolapse support which comprises first body having a first angle and a second angle, a pair of first arms and a pair of second arms. The implant for pelvic organ prolapse support of the present invention can treat cystocele and stress urinary incontinence simultaneously, and can optionally combine with an implant for posterior vaginal wall prolapse support and an auxiliary supporter to treat cystocele, stress urinary incontinence, enterocele, uterine prolapse, rectocele prolapse, anal prolapse, and vaginal vault prolapse at one time.Type: GrantFiled: December 2, 2014Date of Patent: January 8, 2019Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL TAIWAN UNIVERSITY HOSPITALInventors: Ho-Hsiung Lin, Ting-Chen Chang