Abstract: The present invention provides a method for treatment or prevention of cancer through novel action mechanism, namely, through inhibition of a riboflavin pathway. The method for treatment or prevention of cancer comprises administering an RF pathway inhibitor to a subject in need thereof.

Abstract: A pattern generation device includes a memory and a processor coupled to the memory. The processor is configured to generate pattern data corresponding to a pattern of a metal layer based on a generation condition, determine whether the generated pattern data satisfies a predetermined condition, return to generate the pattern data when the predetermined condition is not satisfied, calculate a characteristic of the pattern or an element or circuit having the pattern when a high-frequency signal is inputted to a first portion and a high-frequency signal is outputted from a second portion by performing an electromagnetic field analysis based on the pattern data when the predetermined condition is satisfied, determine whether the calculated characteristic is within a target range, change the generation condition when the calculated characteristic is not within the target range, and return to generate the pattern data after changing the generation condition.

Abstract: An aqueous gel that is prepared by gelling a polymer components, the polymer components containing polymer A, which is obtained by polymerizing a monomer component containing a betaine monomer represented by the formula (I): wherein R1 represents hydrogen atom or an alkyl group, R2 represents an alkylene, arylene, aralkylene, —COOH— or —CONH— group; R3 and R4 represent an alkyl group, and R5 represents an alkylene group, and a polymer B, which is obtained by polymerizing a monomer component containing an acidic monomer represented by the formula (II): wherein R1 represents hydrogen atom or an alkyl group; R6 represents an optionally neutralized sulfonate group, an optionally neutralized phosphate group, or an alkyl, aryl, aralkyl, carboxyl or amino group carrying an optionally neutralized sulfonate group or an optionally neutralized phosphate group.

Abstract: There is provided a photonic bandgap fiber used in a state in which at least a part of the photonic bandgap fiber is bent at radii of 15 cm or greater and 25 cm or less. A large number of high refractive index portions 57 are disposed in a nineteen-cell core type in three layers, and a V value is 1.5 or greater and 1.63 or less. In the high refractive index portions 57, conditions are defined that a relative refractive index difference is ?% and a lattice constant is ? ?m so as to remove light in a higher mode at the bent portion as described above.

Abstract: The problems: It is an object of the present invention to provide an immune regulating agent capable of modulating a receptor function concerning immune regulation of DR6, and a method for screening thereof. The object aims to provide: The present invention relates to an immune regulating agent containing a physiologically active substance having an ability to bind specifically to DR6 and an ability to regulate signal transduction induced by specific binding between DR6 and Sdc1, as an active component. The immune regulating agent of the present invention can be used for treating or preventing diseases caused by excessive or abnormal immune response in mammals or diseases for which enhancement of immune function is desired in mammals, as an immune regulating agent based on a hitherto unknown mechanism, capable of regulating signal transduction induced by specific binding between DR6 and Sdc1.

Abstract: There is provided a photonic bandgap fiber used in a state in which at least a part of the photonic bandgap fiber is bent at radii of 15 cm or greater and 25 cm or less. A large number of high refractive index portions 57 are disposed in a nineteen-cell core type in three layers, and a V value is 1.5 or greater and 1.63 or less. In the high refractive index portions 57, conditions are defined that a relative refractive index difference is ?% and a lattice constant is ? ?m so as to remove light in a higher mode at the bent portion as described above.

Abstract: A plant biomass; a solid catalyst which can catalyze the hydrolysis of the biomass; and a method for hydrolyzing a plant biomass, which is characterized by a step of heating a mixture containing an inorganic acid and water and which has high glucose yield and high glucose selectivity. As the inorganic acid, hydrochloric acid can be used. The pH value is adjusted to 1.0 to 4.0. As the solid catalyst, activated carbon or the like can be used.

Abstract: Electro-conductive fibers comprise synthetic fibers and an electro-conductive layer containing carbon nanotubes and covering a surface of the synthetic fibers, and the coverage of the electro-conductive layer relative to the whole surface of the synthetic fibers is not less than 60% (particularly not less than 90%). The electric resistance value of the electro-conductive fibers ranges from 1×10?2 to 1×1010 ?/cm, and the standard deviation of the logarithm of the electric resistance value is less than 1.0. The thickness of the electro-conductive layer ranges from 0.1 to 5 ?m, and the ratio of the carbon nanotubes may be 0.1 to 50 parts by mass relative to 100 parts by mass of the synthetic fibers. The electro-conductive layer may further contain a binder. The electro-conductive fibers may be produced by immersing the synthetic fibers in a dispersion with vibrating the synthetic fibers to form the electro-conductive layer adhered to the surface of the synthetic fibers.

Abstract: The present invention is directed to realize a stable and highly-efficient quantum communication without being influenced by the jitter of the heralding signal. In regard to the quantum encryption transmitting apparatus 200, the pulse-driven heralded single-photon source 201 generates a photon pair, outputs one photon of the photon pair, and outputs the other photon of the photon pair as a heralding signal. The timing adjuster 202 synchronizes the heralding signal with a clock signal for pulse driving the pulse-driven heralded single-photon source 201, and outputs as a trigger signal. The quantum communication modulating unit 203 implements the signal modulation to a quantum signal, in timing with the trigger signal, and transmits the quantum signal to the quantum encryption receiving apparatus 300 via the quantum communication path 101. The heralding signal transmitting unit 205 transmits the heralding signal to the quantum encryption receiving apparatus 300 via the heralding signal communication path 102.

Abstract: Matching processing reconstructs divided lost regions, which are obtained by dividing a lost region in an image of a Frame t into regions each including N×N pixels as a unit, from corresponding regions of an estimated image of a previously reconstructed Frame t?1 using a boundary matching method. Estimation pre-processing calculates local regions of the estimated image of Frame t?1, which correspond to local regions of each divided lost region in the image of Frame t using a block matching method, and calculates second motion vectors for respective pixels from local regions associated with region in the image of Frame t?1 for all pixels L×L included in each local region of divided lost region. Original image estimation processing defines a transition model and observation model from the result obtained by the estimation pre-processing, and estimates an original image using a Kalman filter algorithm.

Abstract: A phospholipid derivative useful for the preparation of liposomes for efficient uptake of an antitumor agent or a gene intracellularly by a target tumor cell, which comprises a residue of an alcohol compound and a residue of a phospholipid, and comprising a peptide between the residue of an alcohol compound and the residue of a phospholipid, and wherein (a) the alcohol compound is an alcohol compound selected from poly(alkylene glycols) and the like, (b) the phospholipid is a phospholipid selected from phosphatidylethanolamines, phosphatidylcholines, phosphatidylserines and the like, and (c) the peptide is a peptide comprising a substrate peptide that can serve as a substrate of a matrix metalloproteinase, provided that one amino acid residue or an oligopeptide containing 2 to 8 amino acid residues may bind to one or both ends of the substrate peptide.

Abstract: The present invention is directed to, for example, an oligosaccharide having at an end thereof a 4-position halogenated galactose residue represented by formula (I): (wherein X represents a halogen atom, and R represents a monosaccharide, an oligosaccharide, or a carrier), a transferase inhibitor containing the oligosaccharide, and a method for inhibiting sugar chain elongation reaction in the presence of glycosyltransferase, the method including employing the inhibitor. The invention also provides a method for producing a 4-position halogenated galactose sugar nucleotide represented by formula (II): (wherein each of R1 to R3 represents a hydroxyl group, an acetyl group, a halogen atom, or a hydrogen atom; X represents a halogen atom; and M represents a hydrogen ion or a metal ion), wherein the method employs bacterium-derived galactokinase and bacterium-derived hexose-1-phosphate uridylyltransferase.