Abstract: It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and/or a shogaol as active ingredients.
Type:
Application
Filed:
September 25, 2015
Publication date:
January 14, 2016
Applicants:
National University Corporation ASAHIKAWA MEDICAL COLLEGE, TSUMURA & Co.
Abstract: It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and/or a shogaol as active ingredients.
Type:
Grant
Filed:
February 19, 2008
Date of Patent:
November 24, 2015
Assignees:
National University Corporation ASAHIKAWA MEDICAL COLLEGE, TSUMURA & Co.
Abstract: The present invention provides an iron chelating agent which can selectively chelate iron ions. The iron chelating agent of the present invention includes a compound represented by the following formula (1) or a salt thereof (wherein, ring Z represents an aromatic hydrocarbon ring or an aromatic heterocyclic ring; R1 represents an alkylene group; R2 and R3 each independently represent a hydrogen atom, a hydrocarbon group or a group having chelating ability; and the total coordination number of the groups represented by R2 and R3 is 1 or 2.
Type:
Grant
Filed:
September 18, 2009
Date of Patent:
January 7, 2014
Assignees:
National University Corporation Asahikawa Medical College, Yamagata University
Abstract: The present invention provides an iron chelating agent which can selectively chelate iron ions. The iron chelating agent of the present invention includes a compound represented by the following formula (1) or a salt thereof (wherein, ring Z represents an aromatic hydrocarbon ring or an aromatic heterocyclic ring; R1 represents an alkylene group; R2 and R3 each independently represent a hydrogen atom, a hydrocarbon group or a group having chelating ability; and the total coordination number of the groups represented by R2 and R3 is 1 or 2.
Type:
Application
Filed:
September 18, 2009
Publication date:
August 4, 2011
Applicants:
YAMAGATA UNIVERSITY, National University Corporation ASAHIKAWA MEDICAL COLLEGE