Abstract: A nanometer-size-particle production apparatus and method are provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode. The nanometer-size-particle production apparatus is for synthesizing nanometer size particles in a liquid by means of plasma in the liquid.

Abstract: There is provided a ligament reconstruction type artificial knee joint that can exert a function of an anterior cruciate ligament in an original knee joint. In an artificial knee joint 1 used in a total knee replacement, the artificial knee joint 1 includes: a femur member 10 mounted on a femur distal end DT; a tibia member 20 mounted on a tibia proximal end PE; and an artificial ligament 30 coupling the tibia member 20 and the femur member 10 together. One end of the artificial ligament 30 is coupled to a position where once an anterior cruciate ligament ACL exists in a knee replaced for the artificial knee joint 1 on an inside of a lateral condyle of the femur member 10, and the other end of the artificial ligament 30 is coupled to a position where once the anterior cruciate ligament ACL exists in the knee replaced for the artificial knee joint 1 on an upper side of the tibia member 20.

Abstract: A non-transitory computer-readable recording medium stores a determination program that causes a computer to execute a process including: acquiring at every predetermined time position information and speed information from a vehicle that travels a road; computing, by using the position information and the speed information, a distance by which the vehicle travels from a passage of a first spot at which the road changes from a downward slope to an upward slope to a spot at which the vehicle accelerates over a first predetermined value or a distance by which the vehicle travels from a passage of a second spot at which the road changes from an upward slope to a downward slope to a spot at which the vehicle decelerates over a second predetermined value; and determining degradation of driving ability of a driver who drives the vehicle based on the distance.

Abstract: The present invention provides an artificial knee joint that can reconstruct an anterior cruciate ligament in a state close to an original function. An artificial knee joint (1) that is used in a total knee replacement includes a femur member (10) and a tibia member (20). The tibia member (20) has a ligament insertion hole (20h) which pierces the tibia member (20) and which is formed at a position where once an anterior cruciate ligament (ACL) exists in a knee replaced for the artificial knee joint (1). Therefore, a ligament can be provided such that a distal end (DT) of a femur (F) and a proximal end (PE) of a tibia (T) are joined to each other by passing the ligament through the ligament insertion hole (20h), which allows the anterior cruciate ligament (ACL) to be reconstructed so as to be in the substantially same state as a knee replaced for the artificial knee joint (1).

Abstract: Disclosed herein is a functional material having the function of detecting a predetermined substance or the like present in a sample with high accuracy even when the amount of the sample is small, and a method for producing the functional material. The functional material includes a channel part 10 that allows a liquid to pass therethrough, and the channel part 10 is made of a water-permeable material 11 containing a water-impermeable material 12. The water-impermeable material 12 is placed between pieces of the water-permeable material 11, and therefore voids 10h can be formed between the water-impermeable material 12 and the water-permeable material 11. That is, a network of the voids 10h can be formed in the channel part 10. A liquid sample supplied to the channel part 10 is allowed to move while being allowed to penetrate into the voids 10h.

Abstract: A technique for highly efficient production of ?-amino butyric acid (GABA) using mochi barley of the group of mules barley, as a raw material. The technique converts glutamic acid into GABA due to the glutamate decarboxylase contained in the mochi barley so GABA-mochi barley grains and GABA-mochi barley bran and GABA-containing bran supernatant can be produced highly-efficiently by mixing mochi barley grains, which have been polished in a barley milling device to an extent of 2% or more and less than 20%, with a glutamic acid solution, which has a concentration of 0.1 to 3% and a pH value of 2 to 9, and soaking the barley in the solution at room temperature for 1 hour or more to overnight or, after soaking in the solution similarly for 1 hour or more to overnight, draining the barley grains, and keeping it overnight at room temperature.

Abstract: A nanometer-size-particle production apparatus is provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode.

Abstract: A nanometer-size-particle production apparatus is provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode.

Abstract: This invention provides a plant health diagnostic method and a plant health diagnostic device for detecting initial disorder of a plant individual body carrying pests or the like in a large-scale plant cultivation field. The plant health diagnostic method is for diagnosing a health state of a plant in accordance with chlorophyll fluorescence emitted from chlorophyll of a plant body. The method includes: obtaining a first minimum point s after a maximum point p having largest chlorophyll fluorescence intensity and a first maximum point m after the minimum point s on a time course curve for the chlorophyll fluorescence intensity; defining chlorophyll fluorescence intensity values at the minimum point s and the first maximum point m after the minimum point s as S and M, respectively; and comparing the value S and the value M to evaluate the state of the plant.

Abstract: Provided are a detection method for a myriad of proteins involved in an autoimmune disease with high sensitivity and high efficiency, and an analysis method for data resulting from the detection method. In order to construct the detection method and analysis method, there is provided means for comprehensively analyzing the proteins involved in an autoimmune disease by bringing a mammal-derived protein expressed in a cell-free protein synthesis system into contact with a sample derived from a patient with an autoimmune disease to detect autoantibody production, and subjecting the detected data to statistical analysis processing, and further, gene ontology analysis and/or pathway analysis.

Abstract: A shared antenna communicates radio waves with different frequencies or different polarization characteristics, and has a simple configuration that can be placed in a small device. The antenna includes a plurality of loops of the shape of a cross in a spiral fashion and includes a gap provided at a certain midpoint in the spiral loops and a power supply portion provided in a central portion. The distance of the gap is set such that electromagnetic coupling is caused at a first frequency and no electromagnetic coupling is caused at a second frequency different from the first frequency.

Abstract: Provided is a composition that contains an antisense oligonucleotide to a micro RNA and is capable of inhibiting the growth of cancer cells. The present invention, as one aspect, relates to a composition for suppressing the growth of human cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-133a, hsa-miR-133b, hsa-miR-346 and hsa-miR-361-3p. The present invention, as another aspect, relates to a composition for suppressing the growth of human head/neck cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-92a, hsa-miR-133a, hsa-miR-133b, hsa-miR-139-5p, hsa-miR-197, hsa-miR-328, hsa-miR-346, hsa-miR-361-3p, hsa-miR-605, hsa-miR-766, hsa-miR-1228, hsa-miR-1252, hsa-miR-1260 and hsa-miR-1271.

Abstract: Provided are a nitric oxide detection element capable of detecting NO gas contained in a mixed gas at a high speed even when the amount thereof is a super trace amount of ten and several parts per billion; and a process for producing the element. In a nitric oxide detection element having a substrate 12 and a sensing film 11 formed on a surface of the substrate, the sensing film is composed of nitric oxide sensing particles and a polymer adhesive. The nitric oxide sensing particles are produced by adsorbing a dye having a porphyrin skeleton and having, as a central metal, divalent cobalt onto surfaces of inorganic particles.

Abstract: The purpose of the present invention is to provide a method for treating autoimmune diseases. Disclosed is a method or the like for the treatment of autoimmune diseases, which utilizes an antigen-specific tolerogenic antigen presenting cell. Specifically disclosed are: a method for producing an antigen-specific tolerogenic antigen presenting cell, which is characterized by using carbonic anhydrase I; an immunogenic antigen presenting cell which is specific to carbonic anhydrase I; and a method or the like for the treatment of autoimmune diseases (especially inflammatory bowel diseases), which is characterized by using a tolerogenic antigen presenting cell which is specific to carbonic anhydrase I.

Abstract: Provided are a method for analyzing metastasis of head and neck cancer to a cervical lymph node, and a tumor marker for head and neck cancer used therein. Specifically, provided is a method for analyzing metastasis of head and neck cancer to a cervical lymph node, involving: measuring an expression level of at least one gene selected from the group consisting of genes represented by SEQ ID NOS: 1 to 36 in the sequence listing in a cervical lymph node sample; and comparing the aforementioned expression level with a reference value. Also provided is a tumor marker for head and neck cancer used in the aforementioned method for analyzing cervical lymph node metastasis, including at least one gene selected from the group consisting of genes represented by SEQ ID NOS: 1 to 36 in the sequence listing, and/or an expression product of the aforementioned gene and/or an expression level thereof.

Abstract: Provided is a composition that contains an antisense oligonucleotide to a micro RNA and is capable of inhibiting the growth of cancer cells. The present invention, as one aspect, relates to a composition for suppressing the growth of human cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-133a, hsa-miR-133b, hsa-miR-346 and hsa-miR-361-3p. The present invention, as another aspect, relates to a composition for suppressing the growth of human head/neck cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-92a, hsa-miR-133a, hsa-miR-133b, hsa-miR-139-5p, hsa-miR-197, hsa-miR-328, hsa-miR-346, hsa-miR-361-3p, hsa-miR-605, hsa-miR-766, hsa-miR-1228, hsa-miR-1252, hsa-miR-1260 and hsa-miR-1271.

Abstract: A nanometer-size-particle production apparatus is provided which can prevent the occurrence of waste fluids, and which makes quick and continuous syntheses feasible while suppressing damages to the electrode.

Abstract: In an in-liquid plasma film-forming apparatus having: a vessel 1 being capable of accommodating a substrate “S” and a liquid “L” including raw material therein; an electrode 2 for in-liquid plasma, electrode 2 which is disposed in the vessel 1; an electric power device 3 for supplying electricity to the electrode 2 for in-liquid plasma; the electrode 2 for in-liquid plasma is equipped with: a main electrode 21 having a discharging end 22; an auxiliary electrode 26 not only facing the discharging end 22 but also being disposed between the discharging end 22 and the substrate “S” that face each other; and a plasma generating unit 29 having a space that is demarcated by a surface 22a of the discharging end 22 and a surface 26a of the auxiliary electrode 26 facing the surface 22a, and being for generating plasma by means of electricity being supplied to the main electrode 21.

Abstract: An antenna includes a simple structure and a small null angle, which achieves communication using a circularly-polarized wave. The antenna includes a conductive wire arranged in loops in such a way as to form a cross shape. A part at which two line portions projecting outward from the center portion define a right angle is included in the loop path of the conductive wire. This part allows the antenna to transmit and receive an electromagnetic wave in all directions and have a circular polarization characteristic.

Abstract: Provided are a detection method for a myriad of proteins involved in an autoimmune disease with high sensitivity and high efficiency, and an analysis method for data resulting from the detection method. In order to construct the detection method and analysis method, there is provided means for comprehensively analyzing the proteins involved in an autoimmune disease by bringing a mammal-derived protein expressed in a cell-free protein synthesis system into contact with a sample derived from a patient with an autoimmune disease to detect autoantibody production, and subjecting the detected data to statistical analysis processing, and further, gene ontology analysis and/or pathway analysis.