Abstract: A permanent magnet-embedded motor and a pump device are provided. The permanent magnet-embedded motor includes: a stator, including an annular stator core having teeth and slots disposed in a circumferential direction and coils wound around the teeth; and a rotor, including a rotor core having insertion fitting holes disposed to face the teeth of the stator and disposed in the circumferential direction and permanent magnets inserted and fitted into the insertion fitting holes. The rotor core includes: a groove-shaped recessed part, provided between the insertion fitting holes in the circumferential direction to define an outer circumferential magnetic pole part; a pair of notch parts, provided from both ends toward a center side of the outer circumferential magnetic pole part in the circumferential direction to be recessed inward with respect to an outer circumferential contour; and an outer circumferential magnetic pole surface, sandwiched between the pair of notch parts.

Abstract: Provided are a carbon catalyst, an electrode, and a battery that exhibit excellent activity. A carbon catalyst according to one embodiment of the present invention has a carbon structure in which area ratios of three peaks fbroad, fmiddle, and fnarrow obtained by separating a peak in the vicinity of a diffraction angle of 26° in an X-ray diffraction pattern obtained by powder X-ray diffraction satisfy the following conditions (a) to (c): (a) fbroad: 75% or more and 96% or less; (b) fmiddle: 3.2% or more and 15% or less; and (c) fnarrow: 0.4% or more and 15% or less.

Abstract: A method of detecting a target molecule, the method comprising: forming a complex of a target molecule, a capture oligonucleotide, an oligonucleotide primer, and a single-stranded circular DNA; performing a nucleic acid amplification reaction by rolling circle amplification based on the formation of the complex; and detecting amplified nucleic acid; wherein the single-stranded circular DNA contains a first region, and a second region linked to the 3?-side of the first region, and preferably further contains a sequence complementary to a detection reagent-binding sequence; the primer contains a first aptamer sequence which binds to the target molecule, and a sequence which is linked to the 3?-side of the first aptamer sequence and is complementary to the first region of the single-stranded circular DNA; and the capture oligonucleotide contains a sequence complementary to the second region of the single-stranded circular DNA, and a second aptamer sequence which is linked to the 3?-side of the sequence complemen

Abstract: The present invention aims to provide a fluorescent reagent capable of highly sensitive imaging of a lipid droplet at a level ranging from cultured cells to individuals. A lipid droplet detection reagent including a compound represented by the following General Formula (I) is provided. In the formula, m represents an integer of 0 to 5; n represents an integer of 0 to 5; X is selected from the group consisting of a sulfur atom, an oxygen atom, and a group represented by NR; R is a hydrogen atom or a group represented by —(CH2)yCH3; and y represents an integer of 0 to 5.

Abstract: There is provided with a compound. The compound is represented by formula or a salt thereof. R1 is an aliphatic hydrocarbon group having 10 to 26 carbon atoms.

Abstract: A carbon catalyst has improved catalytic activity, and an electrode and a battery include the carbon catalyst. A carbon catalyst includes a metal and phosphorus atoms, wherein a ratio of a concentration (atomic %) of the phosphorus atoms exhibiting a peak having a peak top within a range of 132.5±0.3 eV and having a full width at half maximum of 2.0±0.5 eV, which is obtained by peak separation of a phosphorus atom P2p peak, with respect to a concentration (atomic %) of carbon atoms in X-ray photoelectron spectroscopic measurement is 0.0005 or more.

Abstract: There is provided with a compound. The compound is represented by formula or a salt thereof. R1 is an aliphatic hydrocarbon group having 10 to 26 carbon atoms.

Abstract: There is provided with a compound represented by Formula or a salt thereof; where A is a linking group represented as —X—NHCO— where X is a C1 to C6 alkylene group, each of R1, R2, R4, R5, R7, R8, R10, and R11 is a hydrogen atom, each of R3, R6, and R9 is a substituent of Formula; R12 is selected from a group of substituents represented by Formulae, R13 is a sulfo group, Ra, Rb, and Rc are substituents independently selected from C1 to C6 alkyl groups, and Rd is a hydrogen atom or a C1 to C6 alkyl group, and Rx is a substituent represented by General Formula.

Abstract: The present invention provides a novel molecule that can be used for detection of sIgA. The sIgA-binding nucleic acid molecule of the present invention is characterized in that it binds to secretory immunoglobulin A (sIgA) with a dissociation constant of 37.7 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 12 or a partial sequence thereof, for example. According to the sIgA-binding nucleic acid molecule of the present invention, it is possible to detect sIgA in saliva.

Abstract: A carbon material that is compact and exhibits an excellent hydrogen storage capacity. A carbon material has a specific surface area of 200 m2/g or less and exhibits a hydrogen storage capacity of 1.5×10?5 g/m2 or more at a hydrogen pressure of 10 MPa.

Abstract: A sound insulating member includes a mass section and spring sections. The mass section is disposed so as to have a gap with respect to an outer panel which divides an internal space of a vehicle body and outside thereof, and includes at least a part which has a planar shaped form. The plurality of spring sections are disposed on the mass section at a side of the mass section facing an outer panel. Each of the spring sections has a hollow film member having airtightness and flexibility, and a gas sealed inside the film member. The film member has a first stepped section and a second stepped section that are formed in a stepped shape in an arrangement direction of the outer panel and the mass section.

Abstract: A carbon catalyst, a battery electrode, and a battery, each exhibits excellent catalytic performance. A carbon catalyst contains two kinds of transition metals and has such a carbon structure that an interplanar spacing d002, which is determined from a Bragg angle of one of three diffraction peaks fbroad, fmiddle, and fnarrow obtained by separating a diffraction peak around a diffraction angle (2?) of 26° in an X-ray diffraction pattern of powder X-ray diffraction with a CuK? ray, the one diffraction peak being the diffraction peak fbroad, is 0.374 nm or more.

Abstract: The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula: wherein R1, R2, R3, R4, R5, R6, R7, m, n, p, X, and Y are as defined in the specification, a pharmaceutically acceptable salt thereof.

Abstract: Methods are provided for predicting a response to an anti-PD-1 antibody or anti-PD-L1 antibody therapy based on a new biomarker and for evaluating a malignancy of cancer. The method for predicting a response of a subject to an anti-PD-1 antibody or anti-PD-L1 antibody therapy includes measuring an expression level of LAT1 in a sample collected from a cancer tissue of the subject; and predicting a response of the subject to the anti-PD-1 antibody or anti-PD-L1 antibody therapy based on the expression level of LAT1. The method for evaluating a malignancy of cancer in a subject includes staining a sample collected from a cancer tissue of the subject with an anti-LAT1 antibody and an anti-PD-L1 antibody; and evaluating a malignancy of the cancer in the subject based on a presence or absence of a LAT1-positive and PD-L1-positive site.

Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.

Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: The present invention is characterized by comprising: an acid leaching step for obtaining a leach liquid by causing leaching of, by means of an acid, a metal mixture at least containing vanadium and at least one type of a divalent or trivalent metal selected from nickel, cobalt, manganese, palladium, platinum, copper, and zinc; a complex generation step for adding an ammoniacal alkaline aqueous solution to the leach liquid for adjusting the pH to 10-12 and generating, in the alkaline aqueous solution, an ammine complex of a divalent or trivalent metal ion and an anion complex of a tetravalent and/or pentavalent vanadium ion; a divalent or trivalent metal recovery step for adding a carrier having a carboxyl group to the alkaline aqueous solution in which the ammine complex and the anion complex are generated, causing the divalent or trivalent metal ion in the ammine complex to be selectively adsorbed onto the carrier, and recovering the divalent or trivalent metal ion; and a vanadium recovery step for recoveri

Abstract: A polymer/nanoparticle composite hydrogel can be produced from an industrially readily available general-purpose material and has excellent mechanical and stretching properties. A hydrogel and a method for producing the same, the hydrogel having a self-supporting property and including a silicate salt (A), a polyalkylene glycol (B), and a dispersant (C) for the silicate salt, the hydrogel being characterized in that: the polyalkylene glycol (B) has a weight average molecular weight, number average molecular weight, or viscosity average molecular weight of 500,000 to 20,000,000; and the amount by mass of the polyalkylene glycol (B) is more than 2% by mass and 20% by mass or less relative to 100% by mass of the hydrogel.

Abstract: The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1): where in the chemical formula (1), Su is an atomic group having a sugar skeleton at a nucleoside residue or an atomic group having a sugar phosphate skeleton at a nucleotide residue, and may or may not have a protecting group, L1 and L2 are each independently a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms, X1 and X2 are each independently an imino group (—NR1—), an ether group (—O—), or a thioether group (—S—), and the R1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.

Abstract: A sound insulating member includes a mass section and spring sections. The mass section is disposed so as to have a gap with respect to an outer panel which divides an internal space of a vehicle body and outside thereof, and includes at least a part which has a planar shaped form. The plurality of spring sections are disposed on the mass section at a side of the mass section facing an outer panel. Each of the spring sections has a hollow film member having airtightness and flexibility, and a gas sealed inside the film member. The film member has a first stepped section and a second stepped section that are formed in a stepped shape in an arrangement direction of the outer panel and the mass section.