Abstract: A problem to be solved by the present invention is to provide a non-natural plant in which expression of a gene of interest is induced and a method for producing the same. Particularly, the present invention relates to a non-natural plant in which the expression of the gene is stably induced even in the absence of a physical or chemical stimulus inducing the expression of the gene, and a method for producing the same. When the induction of the expression of the gene enhances a trait of a plant of interest, the present invention provides a non-natural plant in which the trait is enhanced and a method for producing the same. To solve the problem, a non-natural regenerated plant in which the expression of the gene is induced can be produced by forming a callus from a portion of the plant of interest and then subjecting the callus to a treatment by which the expression of the gene is induced.
Type:
Application
Filed:
April 21, 2020
Publication date:
July 7, 2022
Applicant:
National University Corporation Mie University
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Grant
Filed:
May 10, 2019
Date of Patent:
May 31, 2022
Assignees:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Application
Filed:
May 10, 2019
Publication date:
August 29, 2019
Applicants:
National University Corporation MIE University, National University Corporation Nagoya University
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Grant
Filed:
August 13, 2018
Date of Patent:
July 16, 2019
Assignees:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: An imaging plate includes a plurality of wells individually accommodating little fishes, and the little fishes inside the wells are imaged from bottom portions of the wells. In order to adjust imaging posture or imaging positions of the little fishes inside the wells, an imaging little fish management device includes a water unit which supplies and discharges water into and from each well of the imaging plate. The water inside each well flows through a discharge hole provided laterally at a lowermost portion of each well. The water unit is also used to breed the little fishes of the wells of the imaging plate.
Type:
Grant
Filed:
March 31, 2015
Date of Patent:
April 16, 2019
Assignee:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Application
Filed:
August 13, 2018
Publication date:
December 13, 2018
Applicants:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Grant
Filed:
February 21, 2017
Date of Patent:
October 2, 2018
Assignees:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATON NAGOYA UNIVERSITY
Abstract: An object of the present invention is to provide a soft biomass decomposition method, a production method for a target substance from soft biomass, and an enzyme or group of enzymes for decomposing soft biomass. Provided is a soft biomass decomposition method, including a step of bringing an enzyme selected from specific exocellulase, endocellulase, and processive endocellulase into contact with soft biomass such as bagasse and rice straw. Also provided is a production method for a target substance from soft biomass by incorporating the soft biomass decomposition method as a step. Further provided is an enzyme or group of enzymes for decomposing soft biomass selected from specific exocellulase, endocellulase, and processive endocellulase.
Type:
Grant
Filed:
January 29, 2013
Date of Patent:
May 1, 2018
Assignee:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: A protected anode including: an anode including lithium or capable of reversibly incorporating lithium ions; and a lithium ion-conductive protective layer on the anode and including a ceramic composite represented by Formula 1: Li1+aAlbGe2?cMdP3+eO12+f??Formula 1 wherein M is at least one element selected from titanium (Ti), zirconium (Zr), and germanium (Ge), 0?a?1, 0?b?1, 0?c?1, 0?d?0.5, 0?e?0.1, and 0?f?1.
Type:
Grant
Filed:
December 15, 2013
Date of Patent:
March 13, 2018
Assignees:
SAMSUNG ELECTRONICS CO., LTD., NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Inventors:
Dong-joon Lee, Dong-min Im, Victor Roev, Sang-bok Ma, Min-sik Park, Osamu Yamamoto, Nobuyuki Imanishi, Won-sung Choi, Yasuo Takeda
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Grant
Filed:
February 6, 2015
Date of Patent:
December 19, 2017
Assignees:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: A lithium air battery including an electrolyte including lithium ion conductive polymers and lithium salts between a positive electrode and a lithium ion conductive solid electrolyte membrane. The lithium ion conductive polymers are hydrophilic matrix polymers.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
June 13, 2017
Assignees:
SAMSUNG ELECTRONICS CO., LTD, NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Inventors:
Dong-joon Lee, Victor Roev, Young-gyoon Ryu, Dong-min Im, Min-sik Park, Sang-bok Ma, Osamu Yamamoto, Nobuyuki Imanishi, Yasuo Takeda
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Application
Filed:
February 21, 2017
Publication date:
June 8, 2017
Applicants:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: Provided is an antibody production method whereby it is possible to repeatedly acquire antibodies produced by fish without killing the fish. Specifically provided is an antibody production method whereby it is possible to repeatedly acquire the antibodies produced by a fish, without killing the fish, by administering antigens to fish that have blisters.
Type:
Grant
Filed:
March 15, 2012
Date of Patent:
June 7, 2016
Assignee:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: A protected anode for lithium air batteries and a lithium air battery including the protected anode are provided. The protected anode includes: an anode intercalates and deintercalates lithium ions; a lithium ion-conductive solid electrolyte membrane; and a polymer electrolyte disposed between the anode and the ion-conductive solid electrolyte membrane, wherein the polymer electrolyte includes a lithium ion-conductive polymer, a compound represented by Formula 1 having a number average molecular weight from about 300 to about 1,000, and a lithium salt, and an amount of the compound of Formula 1 is from about 10 parts to about 25 parts by weight based on 100 parts by weight of the polymer electrolyte: In Formula 1, R1 to R6, and n are the same as defined in the specification.
Type:
Grant
Filed:
April 25, 2013
Date of Patent:
April 12, 2016
Assignees:
SAMSUNG ELECTRONICS CO., LTD., NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Inventors:
Dong-joon Lee, Dong-min Im, Victor Roev, Sang-bok Ma, Min-sik Park, Osamu Yamamoto, Nobuyuki Imanishi, Won-sung Choi, Yasuo Takeda
Abstract: A protected anode including an anode including a lithium titanium oxide; and a protective layer including a compound represented by Formula 1 below, a lithium air battery including the same, and an all-solid battery including the protected anode: Li1+XMXA2?XSiYP3?YO12??<Formula 1> wherein M may be at least one of aluminum (Al), iron (Fe), indium (In), scandium (Sc), or chromium (Cr), A may be at least one of germanium (Ge), tin (Sn), hafnium (Hf), and zirconium (Zr), 0?X?1, and 0?Y?1.
Type:
Grant
Filed:
September 28, 2012
Date of Patent:
December 29, 2015
Assignees:
SAMSUNG ELECTRONICS CO., LTD., NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: A lithium air battery including: a negative electrode including lithium; a positive electrode using oxygen as a positive active material; and an organic electrolyte, wherein the organic electrolyte includes a metal-ligand complex.
Type:
Grant
Filed:
December 6, 2011
Date of Patent:
November 3, 2015
Assignees:
SAMSUNG ELECTRONICS CO., LTD., NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
June 16, 2015
Assignees:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
Type:
Application
Filed:
February 6, 2015
Publication date:
June 4, 2015
Applicants:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
Abstract: An object of the present invention is to provide a soft biomass decomposition method, a production method for a target substance from soft biomass, and an enzyme or group of enzymes for decomposing soft biomass. Provided is a soft biomass decomposition method, including a step of bringing an enzyme selected from specific exocellulase, endocellulase, and processive endocellulase into contact with soft biomass such as bagasse and rice straw. Also provided is a production method for a target substance from soft biomass by incorporating the soft biomass decomposition method as a step. Further provided is an enzyme or group of enzymes for decomposing soft biomass selected from specific exocellulase, endocellulase, and processive endocellulase.
Type:
Application
Filed:
January 29, 2013
Publication date:
January 8, 2015
Applicant:
NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY
Abstract: A protected anode including: an anode including lithium or capable of reversibly incorporating lithium ions; and a lithium ion-conductive protective layer on the anode and including a ceramic composite represented by Formula 1: Li1+aAlbGe2?cMdP3+eO12+f??Formula 1 wherein M is at least one element selected from titanium (Ti), zirconium (Zr), and germanium (Ge), 0?a?1, 0?b?1, 0?c?1, 0?d?0.5, 0?e?0.1, and 0?f?1.
Type:
Application
Filed:
December 15, 2013
Publication date:
June 26, 2014
Applicant:
National University Corporation Mie University
Inventors:
Dong-joon LEE, Dong-min IM, Victor ROEV, Sang-bok MA, Min-sik PARK, Osamu YAMAMOTO, Nobuyuki IMANISHI, Won-sung CHOI, Yasuo TAKEDA