Abstract: A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5?-untranslated region of an alcohol dehydrogenase gene (ADH5?UTR) derived from a plant.

Abstract: A method for producing an ?-Gal-expressing virus having enhanced immune response to viruses, without requiring the use of any enzyme; an influenza virus vaccine having a high effect (antigenicity), which is produced using an ?-Gal-expressing virus produced by the method; and others. Specifically disclosed are: a method for producing an ?-galactose epitope (Gal?1-3Gal?1-4GlcNAc-R: ?-Gal hereinafter)-expressing virus, which comprises the steps of: (1) introducing an ?1,3- galactosyltransferase gene in an expressible condition into a cell line that does not express ?-Gal to obtain a cell line capable of expressing ?-Gal; (2) inoculating a virus into the cell line capable of expressing ?-Gal to obtain a cell line infected with a virus; and (3) culturing the cell line infected with the virus to obtain a virus expressing ?-Gal from the culture medium..

Abstract: Compositions for protecting transplanted organs, promoting survival of transplanted organs or preserving organs for transplant containing erythropoietin (EPO) as an active ingredient are provided.