Patents Assigned to National University Corporation Shiga University of Medical Science
  • Publication number: 20220409229
    Abstract: Provided is a scissors-type medical treatment tool capable of not only local tissue fixation in an incision/cutting part but also heating on side surfaces of electrodes of a forceps/tweezers type. It has been found out that a tissue part in which tissue is nipped between blades and a tissue part which is brought into abutment against side surfaces of the blades can be heated simultaneously or sequentially by optimizing arrangement of microwave application electrodes and microwave receiver electrodes in a blade pair (in particular, by causing coagulation to be performed evenly on the left and right of the blades), and the present invention has therefore been achieved.
    Type: Application
    Filed: June 20, 2020
    Publication date: December 29, 2022
    Applicant: National University Corporation Shiga University of Medical Science
    Inventors: Tohru TANI, Shigeyuki NAKA, Atsushi YAMADA
  • Patent number: 10842564
    Abstract: It is an object to provide a surgical instrument capable of locally applying microwaves to a minute biological tissue. It has been found that microwaves can be transmitted to a tip of a tapered coaxial body (9) and that microwaves are radiated from the entire central conductor exposed in a major axis direction by decreasing a sectional area (preferably diameter) of a central conductor (1) and a sectional area (preferably inner diameter) of an external conductor gradually or in a step-by-step manner with a ratio between the sectional area (diameter) of the central conductor (1) and the sectional area (inner diameter) of the external conductor being set to be constant, thereby achieving the present invention.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: November 24, 2020
    Assignee: National University Corporation Shiga University of Medical Science
    Inventors: Tohru Tani, Shigeyuki Naka, Hisanori Shiomi
  • Patent number: 10166040
    Abstract: It is an object to provide a surgical tool for excising a hard solid organ such as cirrhotic liver or cutting the organ into a groove without causing bleeding. The inventors of the present invention have found that an organ resection tool including a brush-like structure capable of performing microwave irradiation and/or a brush-like structure capable of receiving a microwave can achieve the above-mentioned object, to thereby arrive at the present invention (organ resection tool including a brush structure capable of performing microwave irradiation). For example, an organ can be crushed or scraped away by manually abrading the organ with a brush of a solid organ resection tool including a brush structure capable of performing microwave irradiation according to the present invention. Further, the organ can be concurrently coagulated through the microwave irradiation to stop bleeding.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: January 1, 2019
    Assignee: National University Corporation Shiga University Of Medical Science
    Inventors: Tohru Tani, Shigeyuki Naka, Hiroya Akabori
  • Publication number: 20180340869
    Abstract: Provided are a cell-holding substrate holder for preparing an observation specimen, and a cell-holding substrate kit, wherein the cell-holding substrate can be easily attached and detached. Also provided is a method of preparing an observation specimen, wherein cell organelles can be satisfactorily observed using an optical microscope, while three problems of cell detachment, drying, and loss of the three-dimensional properties can be simultaneously solved. The cell-holding substrate holder comprises (1) a support plate 1 having a cell-holding substrate arrangement portion 12 having a window portion through which water can pass; and (2) a removable sandwiching plate 2, 3 which has a window portion through which water can pass, and is capable of working in conjunction with the support plate 1 to sandwich and fix a cell-holding substrate 9 in the cell-holding substrate arrangement portion 12. The cell-holding substrate kit 10 comprises the cell-holding substrate holder and a cell-holding substrate 9.
    Type: Application
    Filed: September 14, 2016
    Publication date: November 29, 2018
    Applicant: National University Corporation Shiga University of Medical Science
    Inventor: Ken-ichi MUKAISHO
  • Patent number: 8313483
    Abstract: Provided is an operating tool for organism, in particular, a microwave endoscope forceps. In terms of the operating tool for organism, provided is a multifunctional operating tool which has holding and scissors functions simultaneously, and may further perform coagulation (tissue fixation) by microwaves. The operating tool has no definite fulcrum, and has both the holding and scissors functions with a simple structure by deforming a long-track rod called beam. Two blades are insulated from each other so as to allow microwave current supply. With this structure, an operating tool having three functions, i.e., “a holding function”, “a coagulating function”, and “a cutting function” with a single tool may be developed.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: November 20, 2012
    Assignee: National University Corporation Shiga University of Medical Science
    Inventors: Makoto Hosaka, Tohru Tani, Yoshimasa Kurumi, Shigeyuki Naka
  • Publication number: 20100023001
    Abstract: Provided is an operating tool for organism, in particular, a microwave endoscope forceps. In terms of the operating tool for organism, provided is a multifunctional operating tool which has holding and scissors functions simultaneously, and may further perform coagulation (tissue fixation) by microwaves. The operating tool has no definite fulcrum, and has both the holding and scissors functions with a simple structure by deforming a long-track rod called beam. Two blades are insulated from each other so as to allow microwave current supply. With this structure, an operating tool having three functions, i.e., “a holding function”, “a coagulating function”, and “a cutting function” with a single tool may be developed.
    Type: Application
    Filed: November 8, 2007
    Publication date: January 28, 2010
    Applicant: National University Corporation Shiga University of Medical Science
    Inventors: Makoto Hosaka, Tohru Tani, Yoshimasa Kurumi, Shigeyuki Naka
  • Patent number: 7582427
    Abstract: An object of this invention is to provide a method for assaying, predicting or assessing drug metabolism by effectively detecting (a) mutation(s) in a gene coding for UGT. A gene coding for UGT comprises 5 exons, and since the regions of exons 2 through 5 are common to each isoform of UGT1, by assaying a mutation in the common regions, particularly a mutation in exon 5 region, and further adding the detection of (a) mutation(s) in a plurality of exon regions, mutations of UGT1 gene can effectively assayed. A nucleic acid chip using nucleic acid probes is used as a way of detecting (a) mutation(s).
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: September 1, 2009
    Assignee: National University Corporation Shiga University of Medical Science
    Inventors: Hiroshi Sato, Yoshihide Fujiyama, Kazuo Yamamoto