Patents Assigned to National University Corporation
  • Bonding system and bonding method
    Patent number: 11787126
    Abstract: A bonding system includes a supporting jig having a mounting surface on bonding substrates which are mounted, a bonding device that sandwiches and welds the bonding substrates between itself and the mounting surface, an articulated robot to which the bonding device is attached, and a control unit that controls the articulated robot and the bonding device.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: October 17, 2023
    Assignees: TOYOTA CUSTOMIZING & DEVELOPMENT CO., LTD., AISIN SEIKI KABUSHIKI KAISHA, TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, TORAY INDUSTRIES, INC., TEIJIN LIMITED, KOMATSU LTD., SUBARU CORPORATION
    Inventors: Kenji Furuyashiki, Hiroshi Yuchi, Satoshi Hirawaki, Yoshinori Yamamori, Takayuki Mori, Yoshihiro Iwano, Kazuaki Amaoka
  • Sampling device
    Patent number: 11788935
    Abstract: A sampling apparatus 1 samples a culture medium in a bioreactor 11. A pump 21 circulates the culture medium in the bioreactor 11 via a flow path 41 by leading out the culture medium from the bioreactor 11 into the flow path 41 and introducing the culture medium from the flow path 41 into the bioreactor 11. A valve 22 is provided in the middle of the flow path 41, and switches a flow path such that the culture medium circulated in the flow path 41 flows out to a branch flow path 42 to be sampled.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: October 17, 2023
    Assignees: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, SHIMADZU CORPORATION
    Inventors: Aya Torai, Yoshihiro Matsumoto, Tomohisa Hasunuma
  • Moving control method, moving control device, moving control system, program, and storage medium for multi-vehicle
    Patent number: 11789444
    Abstract: A movement control method for a multi-vehicle system for moving multiple vehicles to target positions individually set for the vehicles includes: acquiring first positions of the vehicles; determining control input for moving the vehicles from the first positions to second positions away from the target positions by a first distance or more while the vehicles satisfy a predetermined condition; and updating the first distance to be a shorter distance when a distance between the second position and the target position of each of the vehicles becomes equal to or more than the first distance and within an updating distance.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: October 17, 2023
    Assignees: MITSUBISHI HEAVY INDUSTRIES, LTD., NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
    Inventors: Yasuo Fujishima, Kazushige Takaki, Shunichi Azuma
  • MINIATURIZED CYTIDINE DEAMINASE-CONTAINING COMPLEX FOR MODIFYING DOUBLE-STRANDED DNA
    Publication number: 20230323335
    Abstract: The invention provides a miniaturized cytidine deaminase-containing complex for modifying DNA formed by combining a nucleic acid sequence recognition module and cytidine deaminase, wherein the nucleic acid sequence recognition module specifically binds to a target nucleotide sequence of double-stranded DNA, the cytidine deaminase is composed of an amino acid sequence composed of a region of amino acid residues at positions 30-150 of SEQ ID NO: 1, an ortholog thereof, an amino acid sequence having mutations of one or several amino acids therein, or an amino acid sequence having at least 90% similarity thereto, and the targeted site of the double-stranded DNA is modified.
    Type: Application
    Filed: September 6, 2021
    Publication date: October 12, 2023
    Applicant: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY
    Inventors: Keiji NISHIDA, Ang LI, Hitoshi MITSUNOBU
  • LIVING BODY COMPRESSING CLIP
    Publication number: 20230320810
    Abstract: A living body compressing clip 100 includes a clip body 1 with metallic arm parts 5a and 5b configured to hold a living body tissue. The clip body 1 includes compressing pieces 10 that protrude from distal end parts of the arm parts 5a and 5b in a long-side direction of the arm parts 5a and 5b. The compressing pieces 10 are formed from a flexible resin and hold a fluorescent dye. According to the living body compressing clip 100, the compressing pieces 10 causes a vascular network to collapse while holding the living body tissue by the arm parts 5a and 5b. Therefore, when the arm parts 5a and 5b hold the mucosal tissue of the tubular organ and excitation light is applied thereto, the fluorescence emitted by the compressing pieces 10 can be satisfactorily confirmed from the serosal side.
    Type: Application
    Filed: November 30, 2020
    Publication date: October 12, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY, NIREC CORPORATION
    Inventors: Takayuki SATO, Tetsuo SUMIDA
  • FUEL CELL
    Publication number: 20230327145
    Abstract: A fuel flow groove formed in a fuel electrode current collector of a fuel electrode of a fuel cell includes a plurality of flow groove portions disposed in parallel, and a plurality of return groove portions connecting an end portion of one side edge portion or an end portion of the other side edge portion of the flow groove portions of two adjacent groups. Each of the return groove portions has an inner wall surface portion facing the end portion of the flow groove portions in the return groove portions. The inner wall surface portion has a curved surface shape in which a distance facing each other from the inner wall surface portion to the end portion of the flow groove portions, gradually decreases toward both end portions of the inner side wall surface portion in a direction orthogonal to an extending direction of the flow groove portions.
    Type: Application
    Filed: October 14, 2020
    Publication date: October 12, 2023
    Applicants: JTEKT CORPORATION, NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY
    Inventors: Takuya TSUJIGUCHI, Noriyasu HAYASHI, Toshiyuki SAITO, Motoo NAKAI, Atsushi KUBO, Akihiro TAKAZATO
  • ACYLCARNITINE ANALYSIS METHOD AND ACYLCARNITINE ANALYSIS DEVICE
    Publication number: 20230324349
    Abstract: One mode of a method for analyzing acylcarnitine according to the present invention is a method for analyzing C5 acylcarnitine using a tandem mass spectrometer, the method including: a measurement step of performing MRM measurement on a specimen according to at least one of MRM transitions of m/z 24>187, m/z 246>57, m/z 246>41, and m/z 246>29; and a processing step of distinguishing between isovalerylcarnitine and pivaloylcarnitine which is an isomer of isovalervicarnitine in the specimen or determining whether or not C5 acylcarnitine in the specimen includes pivaloylcarnitine, using a measurement result obtained in the measurement step. This makes it possible to satisfactorily distinguish between isovalerylcarnitine and pivaloylcarnitine, which have been conventionally difficult to distinguish.
    Type: Application
    Filed: August 24, 2021
    Publication date: October 12, 2023
    Applicants: Shimadzu Corporation, NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
    Inventors: Takanari HATTORI, Jun WATANABE, Misa TANAKA, Hironori KOBAYASHI, Yoshitomo NOTSU
  • ALLERGIC DISEASE DETERMINATION METHOD AND DETERMINATION SYSTEM
    Publication number: 20230324405
    Abstract: An allergic disease determination method includes contacting probes selected from an allergen and a fragment thereof and a biological sample collected from a subject; detecting a reaction between the probes and an antibody contained in the biological sample; determining a type of the antibody reacted with the probes; inputting data associated with the reaction of each of the at least two types of probes with the antibody and data associated with a type of the bound antibody into a prediction model and acquiring a prediction result; and determining an allergic disease on the basis of the prediction result. The prediction model is a nonlinear model or a model having two or more explanatory variables and two or more terms, the model being created using training data associated with the reaction of at least the probes with the antibody and training data associated with the type of the bound antibody.
    Type: Application
    Filed: September 6, 2021
    Publication date: October 12, 2023
    Applicants: MITSUBISHI GAS CHEMICAL COMPANY, INC., NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Erika SAWANO, Yuki TAKASE, Naoki SHIMOJO, Fumiya YAMAIDE, Taiji NAKANO
  • BIDIRECTIONAL SIGHTLINE-POSITION DETERMINATION DEVICE, BIDIRECTIONAL SIGHTLINE-POSITION DETERMINATION METHOD, AND TRAINING METHOD
    Publication number: 20230320640
    Abstract: A determination device includes an acquisition unit, a first determination unit, a second determination unit, and an output unit. The acquisition unit is configured to acquire a sightline direction of a user and a sightline direction of at least one facing person facing the user. The first determination unit is configured to determine whether a sightline of the user is directed to the facing person based on the sightline direction of the user acquired by the acquisition unit. The second determination unit is configured to determine whether a sightline of the facing person is directed to the user based on the sightline direction of the facing person acquired by the acquisition unit. The output unit is configured to output a feedback to the user and/or an executor based on a result of a determination of the first determination unit and a result of a determination of the second determination unit.
    Type: Application
    Filed: March 30, 2023
    Publication date: October 12, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY, Sumitomo Pharma Co., Ltd.
    Inventors: Toshiya NAKAGUCHI, Kyohei FUKUDA, Eiji SHIMIZU, Yoshiyuki HIRANO, Naomi SHIRAIWA, Yuki IKEDA, Masanori MIYAUCHI
  • Production method for low molecular weight polymer, and production device and production method for melt-blown non-woven fabric
    Patent number: 11781254
    Abstract: A production method for a low molecular weight polymer suitable for a melt-blown non-woven fabric and a production device for melt-blown non-woven fabric, with which a high molecular weight polymer can be reduced in molecular weight by applying a shear force to the high molecular weight polymer without adding an additive. The low molecular weight polymer and the melt-blown non-woven fabric are produced using a continuous high shearing device that applies a shear force to the high molecular weight polymer serving as a raw material by rotation of a screw body to reduce the molecular weight of the high molecular weight polymer so as to obtain a low molecular weight polymer, and cools the low molecular weight polymer by passing the low molecular weight polymer through a passage arranged in the axial direction inside the screw body.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: October 10, 2023
    Assignees: SHIBAURA MACHINE CO., LTD., National University Corporation Kanazawa University
    Inventors: Yuya Sasai, Takafumi Sameshima, Yoshio Iizuka, Kaho Osada, Kentaro Taki
  • Arteriosclerosis and cancer detection method using deoxyhypusine synthase gene as indicator
    Patent number: 11782061
    Abstract: The present inventors have surprisingly found that a deoxyhypusine synthase (DHPS) gene, which was previously reported to correlate with prostate cancer and cervical cancer, is highly responsive to arteriosclerosis or digestive system cancer, whereby the gene can be used as a desired marker for arteriosclerosis or digestive system cancer. The present invention has been accomplished on the basis of this finding. Specifically, the present invention provides a method for determining arteriosclerosis or digestive system cancer, which method includes detecting expression of a deoxyhypusine synthase gene in a test sample (preferably a blood sample), and determining arteriosclerosis or digestive system cancer of a test subject from which the test sample has been obtained, on the basis of an increase in the gene expression as an index.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: October 10, 2023
    Assignees: FUJIKURA KASEI CO., LTD., National University Corporation Chiba University
    Inventors: Rika Nakamura, Hideyuki Kuroda, Go Tomiyoshi, Takaki Hiwasa, Masaki Takiguchi, Naokatsu Saeki
  • Nucleoside derivative and use thereof
    Patent number: 11780874
    Abstract: A nucleoside that is more practical for RNA pharmaceuticals and other applications and use thereof is represented by formula (1) or (2) below, or a salt thereof: (In formula (1), R1 represents a hydrogen atom, a hydroxyl group, a hydroxyl group in which a hydrogen atom is substituted by an alkyl group or alkenyl group, or a protected group, and in formula (2), X represents a halogen atom. In formula (1) and formula (2), R2 and R3 may be the same or different, and each represents a hydrogen atom etc., R4 represents NHR7 (in which R7 represents a hydrogen atom etc., and B represent represents any of a purine-9-yl group, 2-oxo-pyrimidin-1-yl group, substituted purine-9-yl group or substituted 2-oxo-pyrimidin-1-yl group).
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: October 10, 2023
    Assignees: YAMASA CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM
    Inventors: Yoshihito Ueno, Yusuke Maeda, Ryohei Kajino
  • Resin composition for forming phase-separated structure, method for producing structure including phase-separated structure, and block copolymer
    Patent number: 11780948
    Abstract: A resin composition for forming a phase-separated structure includes a block copolymer having a block (b1) formed of a repeating structure of styrene units, the block (b1) being partially substituted with a constituent unit represented by the following General Formula (c1) and a block (b2) having a repeating structure of methyl methacrylate units.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: October 10, 2023
    Assignees: Tokyo Ohka Kogyo Co., Ltd., National University Corporation Hokkaido University
    Inventors: Ken Miyagi, Takahiro Dazai, Toshifumi Satoh, Takuya Isono, Shunma Tanaka
  • Apparatus for manufacturing thermoplastic resin material
    Patent number: 11780124
    Abstract: An apparatus for manufacturing a thermoplastic resin material, including: a mold for molding a base material containing a thermoplastic resin into a predetermined shape; and a transfer mechanism that places the base material in the mold, wherein the transfer mechanism includes a detection mechanism that detects a state of the base material, and a controlling unit that controls operation of the mold and the transfer mechanism.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: October 10, 2023
    Assignees: HONDA MOTOR CO., LTD., KADO CORPORATION, NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM, TORAY INDUSTRIES, INC., TEIJIN LIMITED, SUBARU CORPORATION, TOYOTA JIDOSHA KABUSHIKI KAISHA, KYOWA INDUSTRIAL CO., LTD.
    Inventors: Satoshi Hirawaki, Yoshiaki Matsumoto, Shunya Hatanaka, Takashi Kusaka, Yasunari Kuratani
  • Vector including a translation-impaired dihydrofolate reductase gene cassette and ubiquitously acting chromatin opening element
    Patent number: 11781146
    Abstract: The present invention provides mammalian cell expression vectors that impart to mammalian host cells an ability to produce high levels of foreign gene-derived proteins. A ubiquitously acting chromatin opening element (UCOE) is introduced into an expression vector that has a plasmid DNA integrated into a transcriptional hot spot on the chromosome of a dihydrofolate reductase gene-deficient host cell so that it allows for selection of strains that grow in hypoxanthine-thymidine (hereinafter denoted as HT)-free medium, whereby transformants will produce a protein of interest in increased amounts.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: October 10, 2023
    Assignees: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, FUSO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Yasuhiko Suzuki, Miki Nakagawa, Yayoi Kameda, Satoru Konnai, Tomohiro Okagawa, Naoya Maekawa, Shinya Goto, Yamato Sajiki, Kazuhiko Ohashi, Shiro Murata, Yuzuru Kitahara, Keiichi Yamamoto
  • Method for manufacturing gallium nitride semiconductor device
    Patent number: 11784039
    Abstract: A method for manufacturing a gallium nitride semiconductor device includes: preparing a gallium nitride wafer; forming an epitaxial growth film on the gallium nitride wafer to provide a processed wafer having chip formation regions; perform a surface side process on a one surface side of the processed wafer; removing the gallium nitride wafer and dividing the processed wafer into a chip formation wafer and a recycle wafer; and forming an other surface side element component on an other surface side of the chip formation wafer.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: October 10, 2023
    Assignees: DENSO CORPORATION, HAMAMATSU PHOTONICS K.K., National University Corporation Tokai National Higher Education and Research System
    Inventors: Jun Kojima, Chiaki Sasaoka, Shoichi Onda, Masatake Nagaya, Kazukuni Hara, Daisuke Kawaguchi
  • HUMAN ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF AGAINST CORONAVIRUS SPIKE PROTEIN
    Publication number: 20230312689
    Abstract: It is an object of the present invention to provide antibodies against coronavirus (SARS-CoV-2). It is also an object of the present invention to provide a pharmaceutical composition against coronavirus infection using the antibody. According to the present invention, an antibody or antigen-binding fragment thereof that binds to the receptor-binding domain present in the spike protein of coronavirus and is capable of neutralizing the coronavirus, and a pharmaceutical composition for the prevention or treatment of coronavirus infection containing the antibody or antigen-binding fragment, are provided.
    Type: Application
    Filed: July 9, 2021
    Publication date: October 5, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, The University of Tokyo
    Inventors: Shuzo MATSUSHITA, Yu KAKU, Takeo KUWATA, Yoshihiro KAWAOKA, Masaki IMAI, Seiya YAMAYOSHI
  • GAS MEASURING DEVICE
    Publication number: 20230314354
    Abstract: A gas measuring device includes: a filter to which a power supply that applies a voltage or current is connected, which generates resistance heat, and which combusts a predetermined combustible gas in contact therewith; and a gas sensor configured to detect the combustible gas that has passed through the filter.
    Type: Application
    Filed: March 31, 2023
    Publication date: October 5, 2023
    Applicants: SINTOKOGIO, LTD., National University Corporation TOYOHASHI UNIVERSITY OF TECHNOLOGY
    Inventors: Manase MIZUTANI, Yoshihisa SUZUKI, Toshihiko NODA, Kazuaki SAWADA
  • GAS MEASURING DEVICE
    Publication number: 20230314375
    Abstract: A gas measuring device includes: a magnetic field generation unit configured to generate a magnetic field; and a gas sensor configured to detect a gas that has passed through the magnetic field generated by the magnetic field generation unit.
    Type: Application
    Filed: March 31, 2023
    Publication date: October 5, 2023
    Applicants: SINTOKOGIO, LTD., National University Corporation TOYOHASHI UNIVERSITY OF TECHNOLOGY
    Inventors: Manase MIZUTANI, Yoshihisa SUZUKI, Toshihiko NODA, Kazuaki SAWADA
  • COMPOSITION FOR ENHANCING NAMPT GENE EXPRESSION
    Publication number: 20230310367
    Abstract: An object of the present disclosure is at least to provide a technique for enhancing expression of a NAMPT gene. The object is achieved by a composition for enhancing NAMPT gene expression, the composition containing an equol compound as an active ingredient.
    Type: Application
    Filed: September 1, 2021
    Publication date: October 5, 2023
    Applicants: DAICEL CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Hiroaki YAMAMOTO, Kenichi OOE, Yoshinori KATAKURA