Abstract: Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, synthesizing microbial ensembles based thereon, and forming and administering endomicrobial feed supplements are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.
Type:
Application
Filed:
June 27, 2025
Publication date:
May 28, 2026
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Grant GOGUL, Cameron MARTINO, Norman PITT
Abstract: The disclosure relates to methods for decreasing feed conversion ratios in fowl through administering isolated microorganisms to the fowl. In particular aspects, the disclosure provides methods of decreasing feed conversion ratios in fowl through administration of a Bacillus sp. to the fowl. The disclosure further relates to isolated microorganisms and compositions comprising the same.
Type:
Application
Filed:
May 30, 2025
Publication date:
April 23, 2026
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Grant GOGUL, Cameron MARTINO, Norman PITT
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.
Abstract: The disclosure relates to isolated microorganisms, including novel strains of the microorganisms, synthetic bioensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, synthetic bioensembles, and compositions comprising the same, in methods for modulating the health of equine animals. In particular aspects, the disclosure provides methods of treating and/or preventing colic and shifting the gut microbiome.
Type:
Application
Filed:
November 26, 2024
Publication date:
October 23, 2025
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Cameron MARTINO, Fan YANG, Jordan EMBREE, James GAFFNEY
Abstract: The disclosure relates to methods for decreasing feed conversion ratios in fowl through administering isolated microorganisms to the fowl. In particular aspects, the disclosure provides methods of decreasing feed conversion ratios in fowl through administration of a Bacillus sp. to the fowl. The disclosure further relates to isolated microorganisms and compositions comprising the same.
Type:
Application
Filed:
February 15, 2024
Publication date:
February 13, 2025
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Grant GOGUL, Cameron MARTINO, Norman PITT
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.
Abstract: The disclosure relates to compositions beneficial for ruminant administration. Particularly, the disclosure provides compositions formulated for ruminants that comprise beneficial microbes.
Type:
Application
Filed:
December 22, 2023
Publication date:
November 28, 2024
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Luke PICKING, Grant GOGUL, Janna TARASOVA
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.
Type:
Application
Filed:
November 30, 2023
Publication date:
November 7, 2024
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Cameron MARTINO, Norman PITT, Jordan EMBREE, Corey DODGE
Abstract: Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
Type:
Application
Filed:
December 22, 2023
Publication date:
April 18, 2024
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Luke PICKING, Grant GOGUL, Janna TARASOVA
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
Type:
Grant
Filed:
February 23, 2022
Date of Patent:
February 27, 2024
Assignee:
Native Microbials, Inc.
Inventors:
Mallory Embree, Luke Picking, Grant Gogul, Janna Tarasova
Abstract: The present disclosure provides compositions formulated for ruminants that comprise beneficial microbes. Particularly, the disclosure provides a composition comprising microorganisms with at least 97% sequence identity to any one of SEQ ID NOs: 1-60 and 2045-2107. Such compositions can be used for increasing milk production or improving milk compositional characteristics in ruminants.
Type:
Grant
Filed:
July 6, 2020
Date of Patent:
February 27, 2024
Assignee:
Native Microbials, Inc.
Inventors:
Mallory Embree, Luke Picking, Grant Gogul, Janna Tarasova
Abstract: Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and synthesizing bioreactive modificators based thereon are disclosed. Methods for identifying and utilizing pathways and functionalities of interest based thereon are also disclosed.
Type:
Grant
Filed:
December 28, 2017
Date of Patent:
February 6, 2024
Assignee:
Native Microbials, Inc.
Inventors:
Mallory Embree, James Russell Gaffney, Cameron Joseph Martino
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.
Type:
Application
Filed:
September 29, 2023
Publication date:
January 25, 2024
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Grant GOGUL, Cameron MARTINO, Norman PITT
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.
Type:
Grant
Filed:
June 22, 2021
Date of Patent:
January 16, 2024
Assignee:
Native Microbials, Inc.
Inventors:
Mallory Embree, Cameron Martino, Norman Pitt, Jordan Embree, Corey Dodge
Abstract: The disclosure relates to a novel microbial genus Chordicoccus—and a type strain of the genus, Chordicoccus furentiruminis—along with compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganism, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency and methods of decreasing acidosis.
Type:
Application
Filed:
October 15, 2021
Publication date:
November 30, 2023
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, James GAFFNEY, Sean GILMORE, Jordan EMBREE
Abstract: The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.
Type:
Grant
Filed:
October 18, 2018
Date of Patent:
November 28, 2023
Assignee:
Native Microbials, Inc.
Inventors:
Mallory Embree, Grant Gogul, Cameron Martino, Norm Pitt
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms such as Ruminococcus bovis sp. nov.—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
Type:
Application
Filed:
March 31, 2021
Publication date:
May 4, 2023
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Jordan EMBREE, Sean GILMORE
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.
Type:
Application
Filed:
June 22, 2021
Publication date:
December 8, 2022
Applicant:
Native Microbials, Inc.
Inventors:
Mallory EMBREE, Cameron MARTINO, Norman PITT, Jordan EMBREE, Corey DODGE