Patents Assigned to Naurex, Inc.
  • PROCESS FOR SYNTHESIS OF PEPTIDE COMPOUNDS
    Publication number: 20210198315
    Abstract: Disclosed is a new process for preparing dipyrrolidine peptide compounds such as, for example, GLYX-13. Advantageously, the process may be industrially scalable and cost-effective and use less toxic reagents and/or solvents. Further, the process may be used to prepare peptide compounds having improved purity.
    Type: Application
    Filed: January 31, 2017
    Publication date: July 1, 2021
    Applicant: Naurex, Inc
    Inventor: M. Amin KHAN
  • NMDA receptor modulators and prodrugs, salts, and uses thereof
    Patent number: 10590167
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: March 17, 2020
    Assignee: Naurex, Inc.
    Inventor: Amin Khan
  • N-methyl-D-aspartate receptor modulators and methods of making and using same
    Patent number: 9994614
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: June 12, 2018
    Assignee: Naurex, Inc.
    Inventor: M. Amin Khan
  • NMDA receptor modulators and prodrugs, salts, and uses thereof
    Patent number: 9745342
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: August 29, 2017
    Assignee: Naurex, Inc.
    Inventor: Amin Khan
  • STABLE COMPOSITIONS OF NEUROACTIVE PEPTIDES
    Publication number: 20170049844
    Abstract: The disclosure relates to intravenous formulations of GLYX peptides for treating CNS Disorders such as depression, neuropathic pain, or anxiety.
    Type: Application
    Filed: April 27, 2015
    Publication date: February 23, 2017
    Applicant: Naurex Inc.
    Inventors: DAVID HOUCK, MOHSEN ARGHAVANI
  • SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150368252
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 24, 2015
    Applicant: NAUREX, INC.
    Inventors: John A. Lowe, III, M. Amin Khan
  • Hydroxamic Acid Derivatives, Preparation and Therapeutic Uses Thereof
    Publication number: 20140045943
    Abstract: Disclosed are amino alkyl/aryl hydroxamic acid compounds and pharmaceutical compositions containing such compounds. The disclosed compositions are useful as therapeutics for degenerative diseases in mammal.
    Type: Application
    Filed: March 1, 2013
    Publication date: February 13, 2014
    Applicant: Naurex, Inc.
    Inventor: Naurex, Inc.