Abstract: Methods and pharmaceutical compositions are provided for treating idiopathic intracranial hypertension (III) and cluster headache, wherein a somatostatin mimetic formulated for intranasal administration is administered, including direct nose-to-brain administration.
Type:
Application
Filed:
January 20, 2022
Publication date:
September 19, 2024
Applicant:
NBO PHARMA LLC
Inventors:
Fredric D. PRICE, Barry R. FRANKEL, Dorian BEVEC, Warren WASIEWSKI
Abstract: Methods and therapeutic combinations are provided for treating idiopathic intracranial hypertension (IIH) and cluster headache, comprising administering a somatostatin mimetic such as octreotide formulated for direct nose-to-brain administration, and a carbonic anhydrase inhibitor such as topiramate or acetazolamide, at a dose level and/or dosing regimen lower than effective when administered alone.
Type:
Application
Filed:
February 23, 2022
Publication date:
April 25, 2024
Applicant:
NBO PHARMA LLC
Inventors:
Fredric D. PRICE, Barry R. FRANKEL, Dorian BEVEC, Warren WASIEWSKI