Patents Assigned to Nectagen, Inc.
  • Affinity proteins and uses thereof
    Patent number: 10919981
    Abstract: In general, the invention features a novel CBM32-derived affinity scaffold. In certain embodiments, the scaffold comprises two types of regions: constant regions (CRs) and variable loop regions (VLRs) as depicted in the structure in FIG. 1. We have discovered that the CRs provide structural features that enable overall conformational stability while the intervening sequences corresponding to VLRs tolerate amino acid sequence randomization.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: February 16, 2021
    Assignee: Nectagen, Inc.
    Inventors: Richard J. Suderman, David M. Chao, Daren Rice